Search results for "morphometry"
showing 10 items of 119 documents
Glucagon-like peptide-2 and mouse intestinal adaptation to a high-fat diet.
2013
Endogenous glucagon-like peptide-2 (GLP2) is a key mediator of refeeding-induced and resection-induced intestinal adaptive growth. This study investigated the potential role of GLP2 in mediating the mucosal responses to a chronic high-fat diet (HFD). In this view, the murine small intestine adaptive response to a HFD was analyzed and a possible involvement of endogenous GLP2 was verified using GLP2 (3–33) as GLP2 receptor (GLP2R) antagonist. In comparison with animals fed a standard diet, mice fed a HFD for 14 weeks exhibited an increase in crypt–villus mean height (duodenum, 27.5±3.0%; jejunum, 36.5±2.9%;P<0.01), in the cell number per villus (duodenum, 28.4±2.2%; jejunum, 32.0±2.9%;P&l…
The relationship between genetic risk variants with brain structure and function in bipolar disorder: A systematic review of genetic-neuroimaging stu…
2017
Genetic-neuroimaging paradigms could provide insights regarding the pathophysiology of bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A systematic review of gene-imaging studies involving individuals with BD was conducted across electronic major databases from inception until January 9th, 2017. Forty-four studies met eligibility criteria (N = 2122 BD participants). Twenty-six gene variants were investigated across candidate gene studies and 4 studies used a genome-wide association approach. Replicated evidence (i.e. in >2 studies) suggests that individuals with BD carrying the BDNF Val66Met risk allele could have reduced hippocampal volumes compared …
Relationships between a new slope morphometric index and calanchi erosion in northern Sicily, Italy
2012
The Italian badlands, or “calanchi”, are common landforms in Mediterranean areas including central and southern Italy. Calanchi landforms may be compared to small hydrographic basins. These landforms are characterised by dense, hierarchical and rapidly evolving drainage systems carved into steep clayey slopes and by a sharply alternating pattern of furrows and narrow, generally sharp crests. This work presents a study of morphometric characteristics and a statistical analysis for two sites in northern Sicily (Italy), on outcrops of silty-clay deposits affected by active erosion processes, which give this area a typical calanchi landscape. In particular, factors closely linked to the charact…
Gyral and Sulcal Microsurgical Anatomy
2019
Abstract The complex set of sulci and gyri on the surface of the brain form a map with which neurosurgeons should be familiar when it comes to planning and carrying out their procedures, more particularly in the case of intrinsic brain lesions. Based on the general organization of the lobes and gyral convolutions of the brain, as defined by sulci and fissures, the pre- and intraoperative identification of the anatomical features of each patient is of critical importance. Knowledge of brain morphology is also essential to identify its different functional areas, given that both are closely associated. The correct interpretation of the excellent imaging techniques that are currently available…
Late Pleistocene Human Evolution in Sicily: Comparative morphometric analysis of grotta di San Teodoro craniofacial remains.
2007
Late Pleistocene human evolution in Sicily: comparative morphometric analysis of Grotta di San Teodoro craniofacial remains. D'Amore G, Di Marco S, Tartarelli G, Bigazzi R, Sineo L. Source Laboratorio di Archeoantropologia, Soprintendenza per i Beni Archeologici della Toscana, Via dei Rossi 26/A, 50018 Scandicci, Firenze, Italy. Abstract The paleoanthropological remains from Grotta di San Teodoro near Acquedolci (province of Messina, Italy) represent the oldest and largest skeletal collection yet found documenting human settlement of Sicily. The sample, attributed to the Late Epigravettian (between 14,000 and 10,000 years B.P.), consists of seven variously complete adult individuals (San Te…
Auditory hallucinations in first-episode psychosis: A voxel-based morphometry study
2019
Abstract Background Auditory hallucinations (AH) are a core symptom of psychosis. The brain abnormalities responsible for AH remain controversial due to inconsistent and conflicting findings across studies, with substantial confounding factors, such as chronicity. Few studies have examined the pathological changes that occur in the gray matter (GM) of patients with first-episode psychosis (FEP) and AH. The present study aims to validate the presence and characteristics of these structural abnormalities in relation to the intensity of psychotic symptoms and AH in a larger homogeneous sample than those of previous studies. Methods A magnetic resonance voxel-based morphometric analysis was app…
Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness.
2017
BACKGROUND Glaucoma is a neurodegenerative disease, leading to thinning of the retinal nerve fibre layer (RNFL). The exact influence of ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFL thickness (RNFLT) is unknown and was analysed in a subgroup of the Gutenberg Health Study (GHS). METHODS Global peripapillary RNFLT was measured in 3224 eyes of 1973 subjects (49% female) using spectral-domain optical coherence tomography (SD-OCT). The association of age, sex, ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFLT was analysed using Pearson correlation coefficient and fitting a linear mixed model. RESULTS In the univariable analysis highest…
Cingulo-Insular Structural Alterations Associated with Psychogenic Symptoms, Childhood Abuse and PTSD in Functional Neurological Disorders
2017
Objective Adverse early-life events are predisposing factors for functional neurological disorder (FND) and post-traumatic stress disorder (PTSD). Cingulo-insular regions are implicated in the biology of both conditions and are sites of stress-mediated neuroplasticity. We hypothesised that functional neurological symptoms and the magnitude of childhood abuse would be associated with overlapping anterior cingulate cortex (ACC) and insular volumetric reductions, and that FND and PTSD symptoms would map onto distinct cingulo-insular areas. Methods This within-group voxel-based morphometry study probes volumetric associations with self-report measures of functional neurological symptoms, advers…
A taxonomic reassessment of the Centaurea busambarensis complex (Compositae, Cardueae), with description of a new species from the Egadi Islands (W S…
2017
The results of a statistical biometric study of the Centaurea busambarensis complex, which represents the C. cineraria aggregate in Sicily and its offshore islets, are presented. Seventeen populations, representing all seven previously recognized taxa (four species and three additional subspecies) plus a presumed undescribed one were studied. The statistical analysis (PCA and DA) of 26 morphological characters confirmed these eight taxa as distinct, geographically or ecologically vicarious units of equal weight, not supporting their treatment at different ranks. Consequently, they are recognized here as species, resulting in the description (with illustration) of one of them as new (C. aegu…