Search results for "mort"

showing 10 items of 1955 documents

The prognosis of patients having received optimal therapy for nonvariceal upper gastrointestinal bleeding might be worse in daily practice than in ra…

2010

International audience; BACKGROUND: Combination of endoscopic haemostatic and high-dose intravenous proton-pump inhibitors is considered to be the standard care for patients with acute peptic ulcer bleeding. AIM: This study assessed predictive factors of rebleeding and death in unselected patients presented to our hospital. METHODS: Consecutive patients with nonmalignant bleeding ulcers and stigmata of recent haemorrhage who received optimal treatment, between 22 August 2003 and 15 October 2007, were studied retrospectively. RESULTS: Among 140 included patients, 45 (32%) rebled and 30 received another haemostatic endoscopy, which was successful in 20 cases. In multivariate analysis, the onl…

MaleMultivariate analysisAdministration Oral2-Pyridinylmethylsulfinylbenzimidazoleslaw.inventionHospitals University0302 clinical medicineRandomized controlled trialRecurrenceRisk FactorslawOdds RatioHospital Mortality030212 general & internal medicineInfusions IntravenousPantoprazoleRandomized Controlled Trials as TopicAged 80 and overMortality rateHemostasis EndoscopicGastroenterologyMiddle AgedCombined Modality TherapyIntensive care unit3. Good healthIntensive Care UnitsPeptic Ulcer HemorrhageTreatment OutcomeInjections IntravenousFemale030211 gastroenterology & hepatologyFranceAdultmedicine.medical_specialtyRisk AssessmentYoung Adult03 medical and health sciencesInternal medicinemedicineHumansAgedRetrospective StudiesChi-Square DistributionHepatologybusiness.industryProton Pump Inhibitors[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyOdds ratiomedicine.disease[SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyConfidence intervalSurgeryLogistic ModelsUpper gastrointestinal bleedingRockall scorebusiness
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Health-related quality of life is a prognostic factor for survival in older patients after colorectal cancer diagnosis: A population-based study

2015

International audience; Background: Studies carried out in the context of clinical trials have shown a relationship between survival and health-related quality of life in colorectal cancer patients.Aims: We assessed the prognostic value of health-related quality of life at diagnosis and of its longitudinal evolution on survival in older colorectal cancer patients. Methods: All patients aged >= 65 years, diagnosed with new colorectal cancer between 2003 and 2005 and registered in the Digestive Cancer Registry of Burgundy were eligible. Patients were asked to complete the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at inclusion, three, six …

MaleMultivariate analysisColorectal cancerAppetiteDefinitions0302 clinical medicineQuality of lifeSurveys and QuestionnairesCancer registries030212 general & internal medicineAged 80 and overRelative survivalHazard ratioGastroenterologyScoresPrognosis3. Good healthSurvival RateOncology030220 oncology & carcinogenesisColonic NeoplasmsFemalePerspectivesmedicine.medical_specialtyPredict survivalClinical-TrialsContext (language use)Prognostic factorsFeeding and Eating DisordersAssociation03 medical and health sciencesInternal medicinePatient report outcomemedicineHumansMortalitySurvival rateAgedHepatologyRectal Neoplasmsbusiness.industryElderly-patientsCancer[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologymedicine.diseaseElderly patientsQuality of LifePhysical therapyEuropean-organizationbusinessFollow-Up StudiesDigestive and Liver Disease
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A cohort study found good respiratory, sensory and motor functions decreased mortality risk in older people

2003

Abstract Background and Objective The main aims of this study were to evaluate the separate and joint effects of respiratory, sensory, and psychomotor function, muscle strength, and mobility in predicting mortality in older men and women, and to find a way to control multicollinearity in a multivariate Cox regression model. Methods Mortality was followed for 10 years (1990–2000) in an entire cohort of 75-year-old residents of the city of Jyvaskyla, Finland (born in 1914; N =388). Cox regression models and principal component estimation were employed to study the association between the covariates and mortality. Results The study indicated that, after adjustment for fatal diseases and cognit…

MaleMultivariate analysisEpidemiologyVital CapacityWalkingMotor ActivityVibrationSex FactorsHumansMedicineMortalityRisk factorMuscle SkeletalAgedPsychomotor functionProportional hazards modelbusiness.industryHazard ratioRespiratory Function TestsStandardized mortality ratioSensory ThresholdsCohortFemaleEpidemiologic MethodsbusinessPsychomotor PerformanceCohort studyDemographyJournal of Clinical Epidemiology
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Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

2020

PETHEMA, HOVON, PALG, GATLA cooperative groups.

MaleMultivariate analysisOverweightTOXICITYBody Mass Index0302 clinical medicineLeukemia Promyelocytic AcuteRecurrenceAcute promyelocytic leukemiaAntineoplastic Combined Chemotherapy ProtocolsDIFFERENTIATION SYNDROMEOutcomeAged 80 and overAIDA protocolMercaptopurineMortality rateIncidence (epidemiology)HematologyGeneral MedicineMiddle AgedPrognosisTreatment OutcomeVincristinePopulation Surveillance030220 oncology & carcinogenesisFemalemedicine.symptomUnderweightAdultmedicine.medical_specialtyAdolescentACUTE MYELOID-LEUKEMIADIAGNOSISYoung Adult03 medical and health sciencesInternal medicinemedicineAsparaginaseHumansObesityRisk factorAgedRESPONSE CRITERIAOVERWEIGHTbusiness.industrynutritional and metabolic diseasesANTHRACYCLINEmedicine.diseaseObesityRISK-ADAPTED TREATMENTMethotrexateTRANS-RETINOIC ACIDPrednisonebusinessBody mass index030215 immunologyEuropean Journal of Haematology
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Long-term leisure-time physical activity and other health habits as predictors of objectively monitored late-life physical activity – A 40-year twin …

2018

AbstractIMPORTANCEModerate-to-vigorous physical activity (MVPA) in old age is an important indicator of good health and functional capacity enabling independent living.OBJECTIVETo investigate whether physical activity and other health habits at ages 31-48 years predict objectively measured MVPA decades later.DESIGN, SETTING, AND PARTICIPANTSThis prospective twin cohort study in Finland comprised 616 individuals (197 complete twin pairs, including 91 monozygotic pairs, born 1940-1944), who responded to baseline questionnaires in 1975, 1981, and 1990, and participated in accelerometer monitoring at follow-up (mean age, 73 years).EXPOSURESPrimary exposure was long-term leisure-time physical ac…

MaleMultivariate statisticsFITNESSMonozygotic twinphysical activitylcsh:MedicineDETERMINANTS030204 cardiovascular system & hematologyOverweightCohort StudiesCorrelationHabits0302 clinical medicineEpidemiologyMedicineProspective Studies030212 general & internal medicinelcsh:Sciencetwin stydy2. Zero hungerMultidisciplinarySEDENTARY BEHAVIORRegression analysisMiddle Agedleisure-time3142 Public health care science environmental and occupational healthFemalemedicine.symptomHealth habitsvapaa-aikafyysinen aktiivisuusCohort studymedicine.medical_specialtyPhysical activityArticleSTYLE03 medical and health sciencesLeisure ActivitiesHumansOLDER-ADULTSExerciseSocioeconomic statusAgedMonitoring Physiologickaksostutkimusbusiness.industryDISABILITYMORTALITYlcsh:Rhealth habits030229 sport sciencesTwin studykaksosetpredictorsMOBILITYterveyskäyttäytyminenMultivariate AnalysisRISK-FACTORSlcsh:QFOLLOW-UPbusinessBody mass indexIndependent livingDemographyScientific Reports
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Survival of European patients diagnosed with myeloid malignancies: a HAEMACARE study

2013

Population-based information on the survival of patients with myeloid malignancies is rare mainly because some entities were not recognized as malignant until the publication of the third revision of the International Classification of Diseases for Oncology and World Health Organization classification in 2000. In this study we report the survival of patients with myeloid malignancies, classified by updated criteria, in Europe. We analyzed 58,800 cases incident between 1995 to 2002 in 48 population-based cancer registries from 20 European countries, classified into HAEMACARE myeloid malignancy groupings. The period approach was used to estimate 5-year relative survival in 2000-2002. The rela…

MaleMyeloidMyeloproliferative disorders -- DiagnosisMyelodysplastic–myeloproliferative diseaseshemic and lymphatic diseasesMyelodysplastic Syndromes/embryology/mortalityRegistriesCàncerCancerAged 80 and overMielomeseducation.field_of_studyRelative survivalMyeloid leukemiaArticlesHematologyMiddle AgedEuropemedicine.anatomical_structureMyelodysplastic-Myeloproliferative Diseases/epidemiology/mortalityAplastic anemia -- TreatmentFemaleAdultmedicine.medical_specialtyAdolescentPopulationMyelodysplastic syndromesmyeloid malignancies; survivalmyeloid malignanciesBone marrow -- TumorssurvivalNOEurope/epidemiologyYoung AdultInternal medicinemedicineHumanseducationSurvival analysisddc:613AgedMedul·la òssia -- TumorsEssential thrombocythemiabusiness.industryMyelodysplastic syndromesmedicine.diseaseThrombocytopeniaMyelodysplastic-Myeloproliferative DiseasesSurvival AnalysisMyelodysplastic SyndromesImmunologyMyélomesbusiness
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Sex-specific differences regarding seasonal variations of incidence and mortality in patients with myocardial infarction in Germany

2019

Seasonal variation regarding the incidence and the short-term mortality of acute myocardial infarction (MI) was frequently reported, but data about sex-specific differences are sparse.We analysed the impact of seasons and temperature on incidence and in-hospital mortality of patients with acute MI in Germany between 2005 and 2015.The nationwide sample comprised 3,008,188 hospitalizations of MI patients (2005-2015). The incidence was 334.7/100,000 citizens/year. Incidence inclined from 316.3 to 341.6/100,000 citizens/year (β 0.17 [0.10 to 0.24], P  0.001), while in-hospital mortality rate decreased from 14.1% to 11.3% (β -0.29 [-0.30 to -0.28], P  0.001). Overall, 377,028 (12.5%) patients di…

MaleMyocardial Infarction030204 cardiovascular system & hematology03 medical and health sciencesSex Factors0302 clinical medicineGermanymedicineHumansIn patientHospital Mortality030212 general & internal medicineMyocardial infarctionSex DistributionAcute miAgedRetrospective Studiesbusiness.industryIncidenceMortality rateIncidence (epidemiology)Seasonalitymedicine.diseaseSex specificHospitalizationSurvival RateSummer seasonFemaleSeasonsCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesForecastingDemographyInternational Journal of Cardiology
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Repositioning of the global epicentre of non-optimal cholesterol

2020

Publisher's version (útgefin grein)

MaleMyocardial Ischemia/bloodBLOOD-PRESSUREtriglicéridos0302 clinical medicineCardiovascular diseases ; Risk factorsHDL cholesterol80 and overCARDIOVASCULAR RISK-FACTORSPublic health surveillance//purl.org/pe-repo/ocde/ford#3.02.04 [https]BlóðrásarsjúkdómarSocioeconomicsmediana edadComputingMilieux_MISCELLANEOUSPOPULATIONHypercholesterolemia/bloodAged 80 and overCholesterol HDL/bloodancianoeducation.field_of_studyKólesterólriskitekijätadulto3. Good healthadulto jovenTriglycerides/bloodCardiovascular diseasesGeographyCholesterolManchester Institute for Collaborative Research on AgeingCholesterol LDL/bloodDENSITY-LIPOPROTEIN CHOLESTEROLEndokrinologi och diabetesNCD Risk Factor Collaboration (NCD-RisC)Science & Technology - Other Topics//purl.org/becyt/ford/3 [https]Westernteorema de Bayesmedicine.medical_specialtyResearchInstitutes_Networks_Beacons/MICRAHDLMedicinaHypercholesterolemiahipercolesterolemiaNursingHEART-DISEASEEndocrinology and DiabetesHigh blood cholesterol.HDL-kolesteroliArticleLDLravintoHealth risk assessment03 medical and health sciences//purl.org/becyt/ford/3.3 [https]SDG 3 - Good Health and Well-beingBlood cholesterolHumanseducationSERUM-CHOLESTEROLVLAGAgedScience & TechnologyCholesterolPublic healthOmvårdnadHuman healthVDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710Bayes TheoremATHEROSCLEROSIS SOCIETYRisk factorschemistryLipid-lowering medicationsFaculdade de Ciências SociaisEast and southeast Asiaalueelliset erotInternationalityNutrition and Disease[SDV]Life Sciences [q-bio]kolesterolihumanosMyocardial IschemiaMedizinadolescenteNon-HDL cholesterolBlood lipids030204 cardiovascular system & hematologyisquemia miocárdicachemistry.chemical_compoundCholesterol epidemiologyMEDICATION USEVoeding en ZiekteMedicine and Health SciencesAdolescent; Adult; Aged; Aged 80 and over; Bayes Theorem; Cholesterol HDL; Cholesterol LDL; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Ischemia; Stroke; Triglycerides; Young Adult; Internationality030212 general & internal medicine2. Zero hungerMultidisciplinaryMortality rateRepositioningStroke/blood1. No povertyPublic Health Global Health Social Medicine and EpidemiologycolesterolMiddle AgedVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 7103142 Public health care science environmental and occupational healthPeer reviewStrokeMultidisciplinary SciencesTrend analysis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalelipids (amino acids peptides and proteins)LIPIDSAdultAdolescentGeneral Science & TechnologyPopulationepicentre20-YEAR TRENDSYoung AdultmedicineLife Scienceddc:610accidente cerebrovascularDisease burdenTriglyceridesNutritionHigh density lipoproteinsnon-optimal cholesterolCholesterol HDLinternacionalidadCholesterol LDLTreatmentFolkhälsovetenskap global hälsa socialmedicin och epidemiologi
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The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: Estimates of Radiation-Related Cancer Risks

2007

International audience; A 15-Country collaborative cohort study was conducted to provide direct estimates of cancer risk following protracted low doses of ionizing radiation. Analyses included 407,391 nuclear industry workers monitored individually for external radiation and 5.2 million person-years of follow-up. A significant association was seen between radiation dose and all-cause mortality [excess relative risk (ERR) 0.42 per Sv, 90% CI 0.07, 0.79; 18,993 deaths]. This was mainly attributable to a dose-related increase in all cancer mortality (ERR/Sv 0.97, 90% CI 0.28, 1.77; 5233 deaths). Among 31 specific types of malignancies studied, a significant association was found for lung cance…

MaleNeoplasms Radiation-InducedInternational Cooperation[SDV]Life Sciences [q-bio]Radiation inducedradiation exposurenuclear industrycancer riskWhole-Body Counting030218 nuclear medicine & medical imagingCohort Studiescause of death0302 clinical medicineNuclear industryNuclear ReactorsRisk FactorsNeoplasmscancer mortalityMedicineRadiation injuryRadiationindustryadultarticleleukemiarisk assessmentmethodologycohort analysis3. Good healthmultiple myelomaOccupational DiseasesSurvival Ratefemalepriority journalrisk factorstatistics030220 oncology & carcinogenesisemploymentFemaleionizing radiationradiation doseCohort studyradiation injuryAdultEmploymentBiophysicsRadiation DosageRisk Assessmentsurvival03 medical and health sciencessocioeconomicsOccupational ExposureIndustryfollow upHumansRadiology Nuclear Medicine and imaginghumanRisk factorindustrial workerWhole body countingbusiness.industryNicotiana tabacumCancermedicine.diseasemortalitySurvival Analysislung cancerwhole body countingconfidence intervalRadiation-Inducedoccupational diseasenuclear reactorbusinessNuclear medicineCancer riskDemography
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Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

2020

Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the…

MaleNutritional SciencesSpecific riskContaminación del Aire Interior030204 cardiovascular system & hematologySocioeconomic Factorsystematic analysisGlobal HealthBody Mass IndexGlobal Burden of DiseaseHealth Risk BehaviorHealth Risk BehaviorsDisease studies0302 clinical medicineRisk FactorsMETABOLIC RISKS030212 general & internal medicine11 Medical and Health SciencesFactores de Riesgo2. Zero hungereducation.field_of_studyPublic healthInjuriesPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineGBD; risck factors; attributable burden of disease;3142 Public health care science environmental and occupational health3. Good healthRelative riskEnvironmental healthHealthHypertension/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingGlobal Burden of Diseases Injuries Risk FactorsA990 Medicine and Dentistry not elsewhere classifiedFemaleLeading risk factorsGlobal Health MetricsCohort studyHumanmedicine.medical_specialtySubstance-Related DisordersPopulationUNITED-STATESRisk AssessmentDIETITC-HYBRID03 medical and health sciencesLife ExpectancyUNITED-STATES; MORTALITY; DISABILITY; POLLUTION; CLUSTERS; DIETSDG 3 - Good Health and Well-beingPOLLUTIONGeneral & Internal MedicineEnvironmental healthmedicineHumansGlobal Burden of Disease StudyRisk factoreducationGlobal burdenbusiness.industryPublic healthRisk FactorMORTALITYDISABILITYMalnutritionKlinisk medicinGlobal Burden of DiseasesEnvironmental Exposuremedicine.diseaseEnfermedades//purl.org/pe-repo/ocde/ford#3.02.00 [https]MalnutritionFolkhälsovetenskap global hälsa socialmedicin och epidemiologiYears of potential life lostSocioeconomic FactorsRisk factorsDisease studyRelative riskHyperglycemiaITC-ISI-JOURNAL-ARTICLENAClinical MedicinebusinessCLUSTERSRA
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