Search results for "multiple"
showing 10 items of 2678 documents
Ranking of occupational health and safety risks by a multi-criteria perspective: Inclusion of human factors and application of VIKOR
2021
Nowadays, the Occupational Health and Safety (OHS) is more and more recognized as a crucial process to be properly managed and continuously improved by every organization. Primarily addressed to prevent workers’ injuries and diseases, it positively impacts on productivity, competitiveness and reputation as well as it con-tributes to cost savings in general. OHS management is grounded upon the risk assessment results, on the basis of which defining corrective measures to be taken to reduce risks to acceptable values. In this regard, the paper proposes a Multi-Criteria Decision Making (MCDM) based methodology addressed to the occupational risks prioritization. In order to overcome the shortco…
Artificial Decision Maker Driven by PSO : An Approach for Testing Reference Point Based Interactive Methods
2018
Over the years, many interactive multiobjective optimization methods based on a reference point have been proposed. With a reference point, the decision maker indicates desirable objective function values to iteratively direct the solution process. However, when analyzing the performance of these methods, a critical issue is how to systematically involve decision makers. A recent approach to this problem is to replace a decision maker with an artificial one to be able to systematically evaluate and compare reference point based interactive methods in controlled experiments. In this study, a new artificial decision maker is proposed, which reuses the dynamics of particle swarm optimization f…
A HOLISTIC MULTI-METHODOLOGY FOR SUSTAINABLE RENOVATION
2019
A review of the barriers for building renovation has revealed a lack of methodologies, which can promote sustainability objectives and assist various stakeholders during the design stage of building renovation/retrofitting projects. The purpose of this paper is to develop a Holistic Multi-methodology for Sustainable Renovation, which aims to deal with complexity of renovation projects. It provides a framework through which to involve the different stakeholders in the design process to improve group learning and group decision-making, and hence make the building renovation design process more robust and efficient. Therefore, the paper discusses the essence of multifaceted barriers in buildin…
Entropy characteristics of heart rate wavelet multiscale components in epileptic children before and after seizures
2020
In this work, we analyze the information content of the multiple time scale components of heart rate variability (HRV) in children with focal epilepsy. HRV components are extracted from 30 pediatric patients, monitored 10 min and 10 s before and after focal epileptic seizures, using wavelet multiscale decomposition (with 5, 15, 30, 60, 120, 180 s time scale), and then characterized computing Entropy (E), permutation entropy (PE), conditional entropy (CE) and information storage (IS). Moving from preictal to postictal windows, we find statistically significant differences in the CE and IS values of HRV components at short time scales, which reflect autonomic imbalance and appear as potential…
Teaming up for CAR-T cell therapy
2019
Adoptive cellular therapy using chimeric antigen receptor T-cell (CART) therapy is currently being evaluated in patients with relapsed / refractory multiple myeloma (MM). The majority of CAR-T cell programs now being tested in clinical trials are targeting B-cell maturation antigen. Several recent phase I / II trials show promising preliminary results in patients with MM progressing on proteasome inhibitors, immunomodulatory drugs and monoclonal antibodies targeting CD38. CAR-T cell therapy is a potentially life-threatening strategy that can only be administered in experienced centers. For the moment, CAR-T cell therapy for MM is still experimental, but once this strategy has been approved …
A GIS-MCDM-based road network planning for tourism development and management in Arasbaran forest, Iran.
2019
It is very important for managers to plan a road network that meets all the requirements for tourism development and management. The aim of this study was to evaluate and modify an existing road network for tourism purposes in the Arasbaran protected area. First, the map layers of effective criteria were prepared in GIS and were standardized by a fuzzy logic approach and finally combined considering their relative importance weights obtained through pair-wise comparison technique. A suitability map was then acquired. After that, 14 different scenarios of road network were designed to access the recreational area using PEGGER extension in ArcView. Then, they were evaluated in terms of techni…
Long-range cohesive interactions of non-local continuum faced by fractional calculus
2008
Abstract A non-local continuum model including long-range forces between non-adjacent volume elements has been studied in this paper. The proposed continuum model has been obtained as limit case of two fully equivalent mechanical models: (i) A volume element model including contact forces between adjacent volumes as well as long-range interactions, distance decaying, between non-adjacent elements. (ii) A discrete point-spring model with local springs between adjacent points and non-local springs with distance-decaying stiffness connecting non-adjacent points. Under the assumption of fractional distance-decaying interactions between non-adjacent elements a fractional differential equation in…
Persistent Tonic Facial Contraction: A Local Brain-Stem Sign
1993
Impairment of facial motility associated with contralateral hemiparesis is characteristic of pontine lesions. In the Millard-Gubler and Foville syndromes, involvement of the facial nerve is nuclear or infranuclear, resulting in a peripheral-type palsy. Conditions of pontine origin showing hyperactivity of facial muscles are facial myokymia and Brissaud’s syndrome. Brissaud and Sicard [4] reported low-frequency phasic cramplike facial contractions and contralateral hemiparesis in inflammatory brain-stem processes.
The Playing Brain. The Impact of Video Games on Cognition and Behavior in Pediatric Age at the Time of Lockdown: A Systematic Review
2021
A growing number of children and adolescents play video games (VGs) for long amounts of time. The current outbreak of the Coronavirus pandemic has significantly reduced outdoor activities and direct interpersonal relationships. Therefore, a higher use of VGs can become the response to stress and fear of illness. VGs and their practical, academic, vocational and educational implications have become an issue of increasing interest for scholars, parents, teachers, pediatricians and youth public policy makers. The current systematic review aims to identify, in recent literature, the most relevant problems of the complex issue of playing VGs in children and adolescents in order to provide sugges…
On the Extension of the DIRECT Algorithm to Multiple Objectives
2020
AbstractDeterministic global optimization algorithms like Piyavskii–Shubert, direct, ego and many more, have a recognized standing, for problems with many local optima. Although many single objective optimization algorithms have been extended to multiple objectives, completely deterministic algorithms for nonlinear problems with guarantees of convergence to global Pareto optimality are still missing. For instance, deterministic algorithms usually make use of some form of scalarization, which may lead to incomplete representations of the Pareto optimal set. Thus, all global Pareto optima may not be obtained, especially in nonconvex cases. On the other hand, algorithms attempting to produce r…