Search results for "mutagen"

showing 10 items of 2607 documents

An Autistic Endophenotype and Testosterone Are Involved in an Atypical Decline in Selective Attention and Visuospatial Processing in Middle-Aged Women

2015

Mothers of offspring with autism spectrum disorders (ASD) could present mild forms of their children’s cognitive characteristics, resulting from prenatal brain exposure and sensitivity to testosterone (T). Indeed, their cognition is frequently characterized by hyper-systemizing, outperforming in tests that assess cognitive domains such as selective attention, and fine motor and visuospatial skills. In the general population, all these start to decline around the mid-forties. This study aimed to characterize whether middle-aged women who are biological mothers of individuals with ASD had better performance in the aforementioned cognitive skills than mothers of normative children (in both gro…

AdultAgingAutism Spectrum DisorderEndophenotypesHealth Toxicology and MutagenesisPopulationselective attentionMotherslcsh:Medicinebehavioral disciplines and activitiesArticleDevelopmental psychologymedicineHumansAttentionCognitive skillCognitive declineAutistic Disordereducationcaregivereducation.field_of_studylcsh:RPublic Health Environmental and Occupational HealthCognitionMiddle AgedAutism spectrum disordersmedicine.diseaseAutism spectrum disorderSpainAutism spectrum disorders; caregiver; selective attention; testosterone; womenEndophenotypetestosteroneAgnosiaAutismFemalewomenPsychologyStroop effectInternational Journal of Environmental Research and Public Health
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Synthetic antioxidants: biochemical actions and interference with radiation, toxic compounds, chemical mutagens and chemical carcinogens.

1984

Abstract Biological actions of 4 commonly used synthetic antioxidants — butylated hydroxyanisole, butylated hydroxytoluene, ethoxquin and propul gallate — on the molecular, cellular and organ level are compiled. Such actions may be divided into modulation of growth, macromolecule synthesis and differentiation, modulation of immune response, interference with oxygen activation and miscellaneous. Moreover, an overview of beneficial and adverse interactions of these antioxidants with exogenous noxae is given. Beneficial interactions include radioprotection, protection against acute toxicity of chemicals, antimutagenic activity and antitumorigenic action. Possible mechanisms of the antitumorige…

AdultAntioxidantmedicine.medical_treatmentButylated HydroxyanisoleMutagenAnisolesIn Vitro TechniquesToxicologymedicine.disease_causeKidneyRadiation ToleranceAntioxidantschemistry.chemical_compoundMiceEthoxyquinGallic AcidNeoplasmsmedicineButylated hydroxytolueneAnimalsHumansDrug InteractionsPropyl GallateCarcinogenCarcinogen MetabolismKidney metabolismBiological activityButylated HydroxytolueneRatsBiochemistrychemistryLiverEnzyme InductionAntibody FormationCarcinogensQuinolinesButylated hydroxyanisoleMutagensToxicology
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Maternal Parenting Styles and Glycemic Control in Children with Type 1 Diabetes

2019

The purpose of this study is to examine differences in parenting styles between mothers of children with type 1 diabetes and mothers of healthy children and to explore relationships between parenting styles and glycemic control of children with diabetes. Mothers of 63 children with diabetes and mothers of 83 children without diabetes reported their parenting styles using the Blocks&rsquo

AdultBlood GlucoseMaleglykeeminen indeksitype 1 diabetesHealth Toxicology and MutagenesisControl (management)Mothers030209 endocrinology & metabolismArticle03 medical and health sciencesChild Rearing0302 clinical medicinechildrenPsychological controlDiabetes mellitusParenting stylesmedicineHumans030212 general & internal medicineChildta515GlycemicType 1 diabetesdiabetesParentingChild rearingbusiness.industrynuoruustyypin diabetesPublic Health Environmental and Occupational Healthta3142medicine.diseaseäiditparenting stylevanhemmatDiabetes Mellitus Type 1kontrolliglycemic controlFemalebusinessClinical psychologyInternational Journal of Environmental Research and Public Health
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On the question of extracorporeal hemodialysis in diquat intoxication.

1975

Extracorporeal hemodialyses were carried out in a female patient with severe diquat intoxication. Diquat clearance was on average, 3.17 ml/min. Only 0.84 mg diquat could be eliminated from the blood serum by 11.5 hrs of dialysis. Hemodialysis is therefore not an efficient technique for removing amounts of diquat from the organism that are toxicologically relevant one day after ingestion.

AdultChromatographyTime FactorsHealth Toxicology and Mutagenesismedicine.medical_treatmentPyridinium CompoundsGeneral MedicineToxicologyDiquatExtracorporealExtracorporeal hemodialysischemistry.chemical_compoundBlood serumchemistryParaquatRenal DialysisAnesthesiamedicineIngestionDiquatHumansFemaleHemodialysisDialysisArchives of toxicology
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The Effectiveness of EMOVERE: An Emotional Education Program for Young Couples

2021

Our aim was to assess the effectiveness of EMOVERE, a psychoeducational and experiential program to increase emotion regulation in couples. Forty-four young couples (n = 88) aged between 18 and 36 years old participated in the study (53.4% women

AdultCounselingMaleProgram evaluation050103 clinical psychologyemotion regulationAdolescentSexual BehaviorHealth Toxicology and MutagenesisEmotionslcsh:Medicine050109 social psychologyPersonal SatisfactionArticleYoung Adultyoung adulthoodMultivariate analysis of varianceemotional competencesIntervention (counseling)Humans0501 psychology and cognitive sciencesYoung adultinterventionattachmentcouplesEmotional intelligencelcsh:R05 social sciencesMultilevel modelPublic Health Environmental and Occupational Healthprogram evaluationModerationSexual PartnersFemaleAnalysis of variancePsychologyClinical psychologyInternational Journal of Environmental Research and Public Health
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Examining Gender Differences, Personality Traits, Academic Performance, and Motivation in Ukrainian and Polish Students of Physical Education: A Cros…

2020

Background: This study examined the relationship of academic performance with the Big Five traits of personality, academic motivation, and gender in a cross-cultural context. Methods: Participants in the study were 424 university students of physical education (PE) departments from Poland (53%) and Ukraine (47%). Undergraduates completed a brief version of the International Personality Item Pool (Mini-IPIP) to assess the Five-Factor model of personality, the Academic Motivations Scale (AMS), and grade point average (GPA). Results: Polish PE students scored higher in emotional stability and extroversion and had a higher GPA than Ukrainian PE undergraduates. Gender differences were found in b…

AdultCross-Cultural ComparisonMaleInternational Personality Item Poolcross-cultural differencesHealth Toxicology and Mutagenesismedia_common.quotation_subjectlcsh:Medicine050109 social psychologyContext (language use)Academic achievementBig Five personalityArticleDevelopmental psychology03 medical and health sciencesSex Factors0302 clinical medicineAcademic PerformanceOpenness to experienceHumansPersonality0501 psychology and cognitive sciencesBig Five personality traitsStudentsmedia_commonMotivationPhysical Education and TrainingExtraversion and introversionlcsh:R05 social sciencesPublic Health Environmental and Occupational HealthConscientiousness030229 sport sciencesacademic motivationacademic achievementgender differencesFemalePolandUkrainePsychologyPersonalityInternational Journal of Environmental Research and Public Health
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The HEXACO–100 Across 16 Languages

2020

The HEXACO Personality Inventory–Revised (HEXACO–PI–R) has become one of the most heavily applied measurement tools for the assessment of basic personality traits. Correspondingly, the inventory has been translated to many languages for use in cross-cultural research. However, formal tests examining whether the different language versions of the HEXACO–PI–R provide equivalent measures of the 6 personality dimensions are missing. We provide a large-scale test of measurement invariance of the 100-item version of the HEXACO–PI–R across 16 languages spoken in European and Asian countries (N = 30,484). Multigroup exploratory structural equation modeling and confirmatory factor analyses revealed …

AdultCross-Cultural ComparisonMalePersonality InventoryPsychometricsHealth Toxicology and Mutagenesismedia_common.quotation_subjectScale testBig SixhexacoArts and Humanities (miscellaneous)factorial invarianceHEXACO cross-cultural invariancePersonality triPersonalityCross-culturalHumansMeasurement invarianceBig Five personality traitsmedia_commonCross-culturalESEMCross-cultural studiesn/a OA procedureClinical PsychologypersonalitySEMpersonality; hexaco; ESEM; factorial invarianceFemalePsychologyCognitive psychologyJournal of personality assessment
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MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients

2010

A single-nucleotide polymorphism in the MDM2 promoter (SNP309; rs2279744) causes elevated transcription of this major negative regulator of p53 in several cancer types. We investigated MDM2 SNP309 and CDKN1A (p21/Waf1/Cip1) codon 31 (rs1801270) polymorphisms in 86 cases of cutaneous Kaposi's sarcoma (KS) from African and Caucasian patients, and 210 healthy controls. A significant increase of the MDM2 SNP309 T/G genotype was observed among classic KS cases (odds ratio 2.38, 95% confidence interval 1.0-5.5). Frequencies of CDKN1A codon 31 genotypes were not significantly different between cases and controls. The results suggest that the MDM2 SNP309 G allele may act as a susceptibility gene fo…

AdultCyclin-Dependent Kinase Inhibitor p21MaleGenotypeHealth Toxicology and MutagenesisClinical BiochemistryBlack PeopleBiologyPolymorphism Single NucleotideBiochemistryWhite PeopleYoung AdultGene FrequencyRisk FactorsGenotypemedicineHumansGenetic Predisposition to DiseaseAlleleYoung adultSarcoma KaposiKaposi's sarcomaAllele frequencyAgedAged 80 and overProto-Oncogene Proteins c-mdm2Odds ratioMiddle Agedmedicine.diseaseConfidence intervalImmunologyCancer researchFemaleSarcomaTumor Suppressor Protein p53
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Influence of Puerperal Health Literacy on Tobacco Use during Pregnancy among Spanish Women: A Transversal Study.

2020

Background: Despite the fact that tobacco use during pregnancy produces adverse perinatal effects, some women continue to smoke. Health literacy (HL) is essential for health outcomes in adults. However, little is known about HL in pregnant women or postpartum women. The study aimed to analyse the relationship between the degree of HL of women during the early puerperium and tobacco use during pregnancy. Methods: A multicentre, descriptive, cross-sectional study was carried out with women in the early puerperium in a region of eastern Spain, between November 2017 and May 2018. Their HL level was obtained using the Newest Vital Sign (NVS) tool. Multivariate logistic models were adjusted to es…

AdultEducació sanitàriaHealth Toxicology and Mutagenesismedicine.medical_treatmentEmbaràsPsychological interventionlcsh:MedicineHealth literacytobacco useToxicologyArticle03 medical and health sciences0302 clinical medicinePregnancyTabacmedicineHumans030212 general & internal medicinetobacco smokingSocioeconomic statusPregnancy030505 public healthbusiness.industrylcsh:RPostpartum PeriodPublic Health Environmental and Occupational HealthHealth literacyOdds ratiomedicine.diseaseHealth equityConfidence intervalCross-Sectional StudiesSpainSmoking cessationFemalepregnancyPregnant Women0305 other medical sciencebusinessRAhealth literacyDemographyInternational journal of environmental research and public health
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Task and Ego Orientation in Sport Questionnaire (TEOSQ): Psychometric properties in its digital version

2022

The Task and Ego Orientation in Sport Questionnaire’s (TEOSQ’s) psychometric properties have been explored in previous studies but never in its digital version, which facilitates data collection. The objective of this study was to analyze the psychometric properties of the online TEOSQ by MenPas 1.0. The sample was composed of 2320 users (58.4% women; 41.6% men), between 18 and 65 years old (M = 25.27, SD = 7.39). The methods used were Confirmatory Factor Analysis (CFA) and invariance analysis from the original 13-item model. The CFA was corrected for all samples (CFI = 0.92–0.94, TLI = 0.93–0.95, RMSEA = 0.07, SRMR = 0.06; df = 64; Bollen-Stine Bootstrap p = 0.02–0.07): general sample (χ2 …

AdultEgoMaleEsportsAdolescentPsychometricsPsicologia socialHealth Toxicology and MutagenesisInvariancePublic Health Environmental and Occupational HealthReproducibility of ResultsMiddle AgedAchievement goalsPsychometric propertiesYoung AdultSurveys and QuestionnairesPsicometríaHumansFemaleachievement goals; sport; invariance; psychometric propertiesFactor Analysis StatisticalSportAged
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