Search results for "myr"
showing 10 items of 273 documents
Influence of surface chemistry on the structural organization of monomolecular protein layers adsorbed to functionalized aqueous interfaces.
1993
The molecular organization of streptavidin (SA) bound to aqueous surface monolayers of biotin-functionalized lipids and binary lipid mixtures has been investigated with neutron reflectivity and electron and fluorescence microscopy. The substitution of deuterons (2H) for protons (1H), both in subphase water molecules and in the alkyl chains of the lipid surface monolayer, was utilized to determine the interface structure on the molecular length scale. In all cases studied, the protein forms monomolecular layers underneath the interface with thickness values of approximately 40 A. A systematic dependence of the structural properties of such self-assembled SA monolayers on the surface chemistr…
Morphological and molecular redescription of the myxozoanUnicapsula pflugfelderiSchubert, Sprague & Reinboth 1975 from two teleost hosts in the M…
2009
Elongate plasmodia with myxosporean spores belonging to the genus Unicapsula, Davis, 1924 were found in the skeletal muscle of the striped seabream, Lithognathus mormyrus (L.), a candidate for the mediterranean aquaculture. The only species of Unicapsula described from the Mediterranean is Unicapsula pflugfelderi Schubert et al. 1975, which occurs in the picarel, Spicara smaris (L.). For morphological and molecular comparison of U. pflugfelderi from S. smaris with Unicapsula sp. from L. mormyrus measurements of plasmodia and spores, ultrastructural details and 18S and 28S rDNA sequences were analysed. Whereas plasmodia were 2-3 times larger in S. smaris than in L. mormyrus (length 2.47-0.81…
Fifty-five-million-year history of oceanic subduction and exhumation at the northern edge of the Caribbean plate (Sierra del Convento mélange, Cuba)
2009
Petrological and geochronological data of six representative samples of exotic blocks of amphibolite and associated tonalite-trondhjemite from the serpentinitic melange of the Sierra del Convento (eastern Cuba) indicate counterclockwise P-T paths typical of material subducted in hot and young subduction zones. Peak conditions attained were 750 � C and 15 kbar, consistent with the generation of tonalitic partial melts observed in amphibolite. A tonalite boulder provides a U-Pb zircon crystallization age of 112.8 ± 1.1 Ma, and Ar ⁄ Ar amphibole dating yielded two groups of cooling ages of 106-97 Ma (interpreted as cooling of metamorphic ⁄ magmatic pargasite) and 87-83 Ma (interpreted as growt…
Anomalous surface diffusion of protons on lipid membranes.
2014
AbstractThe cellular energy machinery depends on the presence and properties of protons at or in the vicinity of lipid membranes. To asses the energetics and mobility of a proton near a membrane, we simulated an excess proton near a solvated DMPC bilayer at 323 K, using a recently developed method to include the Grotthuss proton shuttling mechanism in classical molecular dynamics simulations. We obtained a proton surface affinity of −13.0 ± 0.5 kJ mol−1. The proton interacted strongly with both lipid headgroup and linker carbonyl oxygens. Furthermore, the surface diffusion of the proton was anomalous, with a subdiffusive regime over the first few nanoseconds, followed by a superdiffusive re…
Queen loss increases worker survival in leaf-cutting ants under paraquat-induced oxidative stress
2021
Longevity is traded off with fecundity in most solitary species, but the two traits are positively linked in social insects. In ants, the most fecund individuals (queens and kings) live longer than the non-reproductive individuals, the workers. In many species, workers may become fertile following queen loss, and recent evidence suggests that worker fecundity extends worker lifespan. We postulated that this effect is in part owing to improved resilience to oxidative stress, and tested this hypothesis in three Myrmicine ants: Temnothorax rugatulus, and the leaf-cutting ants Atta colombica and Acromyrmex echinatior . We removed the queen from colonies to induce worker reproduction and subjec…
Myriocin-induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition…
2020
The modification of lipid composition allows cells to adjust membrane biophysical properties in response to changes in environmental temperature. Here, we use adaptive laboratory evolution (ALE) in the presence of myriocin, a sphingolipid (SLs) biosynthesis inhibitor, to remodel the lipid profile of an industrial yeast strain (LH) of Saccharomyces cerevisiae. The approach enabled to obtain a heterogeneous population (LHev) of myriocin‐tolerant evolved clones characterized by its growth capacity at high temperature. Myriocin exposure also caused tolerance to soraphen A, an inhibitor of the acetyl‐CoA carboxylase Acc1, the rate‐limiting enzyme in fatty acid de novo production, supporting a ch…
Dimerization of visinin-like protein 1 is regulated by oxidative stress and calcium and is a pathological hallmark of amyotrophic lateral sclerosis
2014
AbstractRedox control of proteins that form disulfide bonds upon oxidative challenge is an emerging topic in the physiological and pathophysiological regulation of protein function. We have investigated the role of the neuronal calcium sensor protein visinin-like protein 1 (VILIP-1) as a novel redox sensor in a cellular system. We have found oxidative stress to trigger dimerization of VILIP-1 within a cellular environment and identified thioredoxin reductase as responsible for facilitating the remonomerization of the dimeric protein. Dimerization is modulated by calcium and not dependent on the myristoylation of VILIP-1. Furthermore, we show by site-directed mutagenesis that dimerization is…
Interaction of an odorant lactone with model phospholipid bilayers and its strong fluidizing action in yeast membrane
2003
International audience; Some odorant lactones are naturally present in fruits or in fermented products; they can also be used as food additives and can be produced by microorganisms at the industrial scale by biotechnological processes. Gamma-decalactone was previously shown to have antimicrobial properties. We determined by infrared spectroscopy measurements that this compound rapidly diffused into model phospholipid bilayers (within 2 min), modifying the general physical state of a dimyristoyl-L-alpha-phosphatidylcholine (DMPC) film. In vivo, the lactone strongly increased membrane fluidity in the model yeast Yarrowia lipolytica, as evaluated by fluorescence anisotropy measurements. This …
«Hinc Tomyris Crassum male multat»: nota a Naldo Naldi, carm. var. VI 121-138
2020
In questa nota viene proposta l’analisi di un breve episodio che si legge nel carme ‹De virtute› (carm. var. 6, 121-138) del poeta fiorentino Naldo Naldi (1439-1513), relativo alla figura di Marco Licinio Crasso, fin dall’antichità e, poi, nel Medioevo e nell’Umanesimo, tipico exemplum di insaziabile avidità e di avarizia punita. This note proposes the analysis of a short episode that can be read in the poem ‹De virtute› (carm. var. 6, 121-138) of the Florentine poet Naldo Naldi (1439-1513), relating to the figure of Marco Licinio Crasso, since Antiquity and then, in the Middle Ages and Humanism, a typical exemplum of insatiable greed and punished avarice.
Hymenoptera Chalcidoidea inhabiting galls of Cynipidae in Jordan
2008
Twenty-three species of Chalcidoidea (5 Eurytomidae, 4 Torymidae, 2 Ormyridae, 5 Pteromalidae and 7 Eulophidae) are recorded as regular members of the parasitoid fauna inhabiting galls of Cynipidae in Jordan. The occurrence of three additional species, probably only facultatively associated with cynipid galls, is noted. Twenty-two out of the total 26 species were previously unrecorded in the country, while 13 of them are also new for the entire Middle East. Eighteen new host records were detected, together with 24 new plant-parasitoid associations. The biology of each species is briefly commented upon, as well as the presence of a host-related colour variation in some species.