Search results for "nDNA"

showing 2 items of 2 documents

Post-Messinian evolutionary relationships across the Sicilian channel: Mitochondrial and nuclear markers link a new green toad from Sicily to African…

2008

19 páginas, 6 figuras y 3 tables

MalePleistoceneEvolutionAfrica; Animals; Biodiversity; Bufonidae; DNA Mitochondrial; Evolution Molecular; Female; Male; Phylogeny; RNA Ribosomal 16S; SicilyRange (biology)BiogeographyPLEISTOCENESettore BIO/05 - ZoologiaZoologyDNA MitochondrialPHYLOGEOGRAPHYEvolution MolecularRNA Ribosomal 16SDNA POLYMORPHISMMTDNAQH359-425AnimalsSicilyPhylogenyREPTILIAEcology Evolution Behavior and SystematicsmtDNAnDNA green toadSALINITY CRISISmtDNA control regionPOPULATION-GROWTHbiologyBufo balearicusFROGSBiodiversitybiology.organism_classificationBufonidaelanguage.human_languageCOALESCENTPhylogeographyAfricalanguageFemaleBUFO-VIRIDISMediterranean IslandsSicilianResearch ArticleBMC Evolutionary Biology

researchProduct

Jaunu ģenētisko variantu funkcionāla raksturošana izmantojot izolētas pacientu šūnas

2022

Mutācijas gan mitohondriālajā DNS, gan kodola DNS var izraisīt traucējumus mitohondriju oksidatīvās fosforilēšanas sistēmā, kas var būt cēlonis smagām mitohondriālajām slimībām. Mitohondriālo slimību diagnostika ir komplicēta, un tai izmanto lielu laboratorijas metožu klāstu. Darba “JAUNU ĢENĒTISKO VARIANTU FUNKCIONĀLA RAKSTUROŠANA IZMANTOJOT IZOLĒTAS PACIENTU ŠŪNAS” mērķis ir raksturot jaunus ģenētiskos variantus reto ģenētisko slimību pacientiem, izmantojot molekulārās un bioķīmiskās metodes, kā arī perifēros leikocītus un kultivētus fibroblastus. Tika veikta DNS variantu validācija ar Sangera sekvencēšanu, šūnu līniju izveidošana un kultivēšana, mitohondriju izdalīšana no šūnu kultūrām u…

Mitohondriālās slimības/Mitochondrial diseasenDNS/nDNAģenētiskais variants/genetic variantBioloģijaOXPHOSmtDNS/mtDNA

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PEPhysical Sciences and Engineering
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LSLife Sciences
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