Search results for "navi"
showing 10 items of 1983 documents
Learning from the past in the COVID-19 era: rediscovery of quarantine, previous pandemics, origin of hospitals and national healthcare systems, and e…
2020
Abstract After the dramatic coronavirus outbreak at the end of 2019 in Wuhan, Hubei province, China, on 11 March 2020, a pandemic was declared by the WHO. Most countries worldwide imposed a quarantine or lockdown to their citizens, in an attempt to prevent uncontrolled infection from spreading. Historically, quarantine is the 40-day period of forced isolation to prevent the spread of an infectious disease. In this educational paper, a historical overview from the sacred temples of ancient Greece—the cradle of medicine—to modern hospitals, along with the conceive of healthcare systems, is provided. A few foods for thought as to the conflict between ethics in medicine and shortage of personne…
Impact of smoking on COVID-19 outcomes: a HOPE Registry subanalysis
2021
BackgroundSmoking has been associated with poorer outcomes in relation to COVID-19. Smokers have higher risk of mortality and have a more severe clinical course. There is paucity of data available on this issue, and a definitive link between smoking and COVID-19 prognosis has yet to be established.MethodsWe included 5224 patients with COVID-19 with an available smoking history in a multicentre international registry Health Outcome Predictive Evaluation for COVID-19 (NCT04334291). Patients were included following an in-hospital admission with a COVID-19 diagnosis. We analysed the outcomes of patients with a current or prior history of smoking compared with the non-smoking group. The primary …
Baltu filoloģija, 23. sēj., Nr.1
2014
A Phase I/II Dose-Escalation Multi-Center Study to Evaluate the Safety of Infusion of Natural Killer Cells or Memory T Cells As Adoptive Therapy in C…
2021
Abstract Background: Adoptive cell immunotherapies for opportunistic virus in immunocompromised patients using haploidentical memory T cells have shown to be safe and effective. Since severe cases of COVID-19 present a dysregulated immune system with T cell lymphopenia and a hyper-inflammatory state we have proposed that a similar strategy could be proven to be efficient for COVID-19 patients. This is a study protocol of an open-label, multicenter, double-arm, randomized, dose-finding phase I/II clinical trial to evaluate the feasibility, safety, tolerability, and efficacy of the administration of a single dose of allogenic SARS-CoV-2 specific memory CD45RA - T cells and Natural Killer (NK)…
Algunas cuestiones de responsabilidad en la ley 14/2014, de 24 de julio, de navegación marítima
2015
La Ley española de Navegación Marítima ha reformado ampliamente el Derecho marítimo español, regulando prácticamente todos los aspectos de la navegación, tanto públicos como privados. El presente trabajo aborda algunos supuestos de responsabilidad que pueden plantearse en el ámbito de la navegación marítima y que el legislador español ha recogido en esta Ley The spanish Law of Maritime Navigation has reformed widely the spanish Maritime Law, regulatin practically all the aspects of the navigation, both public and privates. This paper approaches some suppositions of responsibility that can appear in the maritime navigation and that the spanish legislator has gathered in this Law.
La multidimensionalidad de una pandemia. Sociedad y Derecho en la era del post-coronavirus
2020
La multidimensionalidad de lecturas que se han abierto derivadas de los efectos del Covid-19 (filosófica, sociológica y jurídica) ofrece una oportunidad para reflexionar sobre algunas dicotomías –además de la ya clásica salud/economía- tales como riesgo-miedo/alteridad, individualismo/comunidad, así como a revisar algunos de los relatos y narrativas que han intentado explicar lo que esta crisis ha supuesto y el escenario post-pandémico que podría configurarse. A partir del análisis de las dimensiones filosófica y sociológica, se pretende sentar las bases para identificar qué cuestiones nucleares inciden en la dimensión jurídica y, a partir de ahí, apuntar algunos parámetros acerca de cómo p…
Delineamientos de desarrollo local en tiempos de incertidumbre: oportunidad para otro tipo de planteamientos / / / \ \ \ Local development outlines i…
2020
Resumen: La pandemia de Covid-19 han impactado en todos los ámbitos sociales y aspectos comunitarios, sociales y subjetivos. En el desarrollo local y regional esta situación ha tenido unos efectos devastadores sobre los que todavía es temprano para evaluar sus efectos, de tal manera que es posible referirse a un “antes” y un “después”. En este escenario y contexto inédito de incertezas y riesgos, es posible referirse a la contingencia como un nuevo marco de descripción de las sociedades, en la que los conceptos teóricos del desarrollo local (y social en general) deberán explorar nuevos conceptos emergentes, como son, el riesgo y el peligro, y con ello, repensar la lógica y teorías del desar…
Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal
2020
The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a …
2022
Invasive mechanical ventilation; COVID-19; Critical care Ventilación mecánica invasiva; COVID-19; Cuidado crítico Ventilació mecànica invasiva; COVID-19; Atenció crítica Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods This is a multin…