Search results for "needle"

Subcutaneous Injection of Drugs: Literature Review of Factors Influencing Pain Sensation at the Injection Site.

2019

The subcutaneous administration route is widely used to administer different types of drugs given its high bioavailability and rapid onset of action. However, the sensation of pain at the injection site might reduce patient adherence. Apart from a direct effect of the drug itself, several factors can influence the sensation of pain: needle features, injection site, volume injected, injection speed, osmolality, viscosity and pH of formulation, as well as the kind of excipients employed, including buffers and preservatives. Short and thin needles, conveniently lubricated and with sharp tips, are generally used to minimize pain, although the anatomic injection site (abdomen versus thigh) also …

German Survey on EUS-Guided Diagnosis and Management of Gastrointestinal Stromal Tumors (GISTs) - Evidence or "Gut-Feeling"?

2015

To examine practice patterns of endosonographers in diagnosing and managing gastrointestinal stromal tumors (GISTs) in Germany.A modified published survey (Ha et al., Gastrointest Endosc 2009) was sent to endosonographic ultrasound (EUS) customers in Germany. The survey was also publicized on the homepage of an EUS interest group. To avoid duplicate opinions, participants were asked to return one survey per institution.142 centers of roughly 850 German EUS centers responded. 25 % were from University hospitals and 74 % from community hospitals. 61 % performed 2 EUS scans for suspected subepithelial lesions/week. Although 97 % of respondents believed that tissue acquisition with CD117 immuno…

Endoscopic ultrasound through‐the‐needle biopsy diagnosis of a pancreatic lymphoepithelial cyst

2019

Diagnostic performance of endoscopic ultrasound through‐the‐needle microforceps biopsy of pancreatic cystic lesions: Systematic review with meta‐anal…

2020

Objectives Endoscopic ultrasound through-the-needle biopsy (EUS-TTNB) is a useful tool for differential diagnosis among pancreatic cystic lesions (PCLs). Cystic fluid cytology (CFC) is recommended by guidelines, but its diagnostic accuracy is about 50%. The aim of this meta-analysis is to assess the clinical impact of EUS-TTNB in terms of technical success (TS), histological accuracy (HA) and diagnostic yield (DY). Methods Original studies in English language on EUS-TTNB were searched in MEDLINE and EMBASE until October 2019. Diagnostic accuracy of EUS-TTNB for identification of mucinous PCLs was calculated using individual diagnostic data of patients who underwent CFC and surgery. Results …

Resistance of Conifer Needle Polyolefin Composites (CNPCs) Against Biodecomposition Caused by Fungi

2017

This study describes the resistance of composites filled with conifer needles to biodecomposition processes caused by a single strain of Aspergillus niger as well as by a consortium of microorganisms present in the compost substrates (forest or spent mushroom composts). The impact of various types of conifer needles on the growth of A. niger was studied to determine whether the filler can show the fungistatic effect. The changes in chemical composition of the composites surfaces were examined using attenuated total reflectance Fourier transform infrared spectroscopy (FTIR/ATR). The results showed that the fungistatic effects of conifer needles polyolefin composites (CNPCs) were associated w…

Dural sac localization using myelography and its application to the lumbosacral epidural in dogs

2020

Background: The techniques described for the identification of the lumbosacral (LS) epidural space in dogs do not guarantee the needle position or an accidental subarachnoid puncture, especially in small size dogs.Aim: To determine the relationship between body weight and the location of the dural sac (DS) using myelography in dogs, and to determine the possibility of subarachnoid puncture during LS epidural based on the position of the DS.Methods: Four masked observers evaluated 70 myelographic studies of dogs, annotating the vertebrae where the DS ended, if it was localized before or after the LS space, and if accidental subarachnoid puncture during LS epidural injection was possible (yes…

PERCUTANEOUS US (ULTRA SOUND) GUIDED FINE NEEDLE ASPIRATION (FNA) OF ENDOTHORACIC NEOPLASM

2022

Introduction: Ultrasound (US)-guided fine needle aspiration (FNA) of percutaneous, transparietal endothoracic lesions, is a useful method in the diagnostic process for anatomopathological characterization. This sampling is a minimally invasive procedure, with a low complication rate and can be performed under loco-regional anesthesia Material and methods: We retrospectively studied (2009 to 2019) the utility of US guided transthoracic FNA in the diagnosis of suspected endothoracic lesions on 54 patients (34 men and 20 women), aged between 44 and 79 years, with pleural, pulmonary or mediastinal neoplasm viewable with an US examination. Results: The definitive diagnosis of malignant or benign…

Assessment of the Mass and Surface Area of the Scots Pine (Pinus sylvestris L.) Needles

2022

The assessment of the surface area of all leaves from a tree crown is regarded as one of the key parameters in scaling ecophysiological processes, such as growth, carbon budget, and water management. The purpose of this study was to investigate the variation of the mass and surface area of Scots pine needles, obtained from trees growing in the same habitat conditions but at different stock densities, therefore occupying different biosocial positions. The mass of needles and the leaf area index (LAI) were determined for an even-aged 33-year-old Scots pine stand located at a fresh mixed coniferous forest site in southwest Poland (50°32′ N; 17°42′ E). The needles, collected…

Treatment of giardiasis reverses "active" coeliac disease to "latent" coeliac disease.

2001

In patients with coeliac disease, a regression of intestinal damage without a gluten-free diet is a very rare event. We describe a young child with diarrhoea, intestinal mucosa atrophy and positive serum anti-endomysial and anti-tissue transglutaminase (anti-tTG) antibodies during intestinal giardiasis infection. He showed normal intestinal mucosa architecture and negative anti-endomysial and anti-tTG antibodies after his giardiasis was cured, although he continued to assume a normal diet. Re-evaluations on a 6-monthly basis showed that he was symptom free, and all haemato-chemical parameters were within normal limits. Three years after the initial diagnosis, a third intestinal biopsy showe…

Diagnostic Performance of Multiparametric Magnetic Resonance Imaging and Fusion Targeted Biopsy to Detect Significant Prostate Cancer

2017

Background/aim Multiparametric magnetic resonance imaging combined with ultrasound-fusion-targeted biopsy of the prostate intends to increase diagnostic precision, which has to be clarified. Patients and methods We performed multiparametric magnetic resonance imaging followed by ultrasound-fusion-guided perineal biopsy in 99 male patients with elevated prostate-specific-antigen and previous negative standard biopsy-procedures. Results In 33/99 patients (33%) no malignancy could be confirmed by histopathology. Low-grade carcinomas (Gleason-Score 6+7a) were found in 42/66 (64%) and high-grade carcinomas (Gleason-Score ≥7b) in 24/66 (36%) men. A high-grade carcinoma corresponded to PI-RADS 4 o…