Search results for "nephrology"
showing 10 items of 673 documents
Force-Time Characteristics and Running Velocity of Male Sprinters during the Acceleration Phase of Sprinting
1988
Abstract In an effort to investigate the force-time characteristics during the acceleration phase of the sprint start, eight male sprinters were used as subjects. Runs up to 3 m were analyzed from film, and force-time parameters were measured on a force platform. In a starting stance the reaction time of the group was .118 ± .016 s and the force production lasted .342 ± .022 s. The maximal resultant force at the moment of maximal horizontal force was 19.3 ± 2.2 N x kg1, and the direction of the force was 32 ± 7°. In the very last instant before leaving the blocks the velocity of the center of gravity was 3.46 ± .32 m x s−1. In the first contact after leaving the blocks there was a braking p…
Psychomotor and Motor Speed in Power Athletes Self-Administering Testosterone and Anabolic Steroids
1988
Abstract The effect of self-administered testosterone and anabolic steroids on psychomotor and motor speed were studied among five top-level power athletes. The experiment included a 26-week intensive strength training period in association with the use of exogenous hormones and a 6-week follow-up after drug withdrawal. Six athletes not using exogenous hormones served as a control group. The results indicated a similar, and in most cases insignificant, improvement (0–10%) in performance in both groups in both the simple and more complicated motor and psychomotor tests. Only in maximal vertical speed related to body weight was there more improvement in the experimental group, from 122.2 to 1…
Mapping the landscape of urology: A new media-based cross-sectional analysis of public versus academic interest.
2018
Objectives To quantify public and academic interest in the urological field using a novel new media-based methodology. Methods We systematically measured public and academic interest in 56 urological keywords and combined in nine subspecialties. Public interest was quantified as video views on YouTube. Academic interest was quantified as article citations using Microsoft Academic Search. The public-to-academic interest ratio was calculated for a comparison of subspecialties as well as for diseases and treatments. Results For the selected 56 urological keywords, we found 226 617 591 video views on YouTube and 2 146 287 citations in the academic literature. The public-to-academic interest rat…
Sleep Apnea and the Kidney
2020
Abstract Purpose of Review There are some uncertainties about the interactions between obstructive sleep apnea (OSA) and chronic kidney disease (CKD). We critically reviewed recent studies on this topic with a focus on experimental and clinical evidence of bidirectional influences between OSA and CKD, as well as the effects of treatment of either disease. Recent Findings Experimental intermittent hypoxia endangers the kidneys, possibly through activation of inflammatory pathways and increased blood pressure. In humans, severe OSA can independently decrease kidney function. Treatment of OSA by CPAP tends to blunt kidney function decline over time, although its effect may vary. OSA may increa…
Urinary incontinence and quality of life: a systematic review and meta-analysis
2021
AbstractBackgroundUrinary incontinence (UI) and low quality of life (QoL) are two common conditions. Some recent literature proposed that these two entities can be associated. However, no attempt was made to collate this literature. Therefore, the aim of this study was to conduct a systematic review and meta-analysis of existing data to estimate the strength of the association between UI and QoL.MethodsAn electronic search of major databases up to 18th April 2020 was carried out. Meta-analysis of cross-sectional and case–control studies comparing mean values in QoL between patients with UI and controls was performed, reporting random-effects standardized mean differences (SMDs) ± 95% confid…
Tubular cell damage may be the earliest sign of renal extrahepatic manifestation caused by Hepatitis C
2021
Publisher Copyright: © 2021 Kaartinen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Chronic kidney disease (CKD) is one of the most well-known extrahepatic manifestations caused by hepatitis C infection (HCV). CKD is typically discovered at a late stage. HCVnephropathy may show different histopathologic patterns, as both glomerular and tubulointerstitial damage have been described. Identification of patients with early renal manifestations would be beneficial to provide treatment and avoid progres…
Radium-223 treatment in castration resistant bone metastatic prostate cancer. Should be the primary tumor always treated?
2019
Introduction: Radium-223 (223Ra) improves symptoms and survival in patients with bone metastatic castration-resistant prostate cancer (mCRPC). Study aim: To evaluate the impact of a previous radical prostatectomy (RP) on the outcome of 223Ra therapy in mCRPC patients. The primary prostate tumor left untreated could progress during 223Ra treatment. Materials and methods: mCRPC symptomatic patients treated with 223Ra were enrolled. Luteinizing Hormone-Releasing Hormone analogue was maintained. No other anticancer therapy was given. 223Ra was administered i.v. at the dose of 55 kBq/kg every 4 weeks for 6 cycles. Patients were stratified according to previous RP or not. Hematological toxicity w…
Hematologic toxicity of radium-223 in elderly patients with metastatic Castration Resistant Prostate Cancer: a real-life experience
2019
Background: Treatment with radium-223 has been shown to increase survival and to delay skeletal events related to bone metastases of patients with metastatic Castration Resistant Prostate Cancer (mCRPC). This treatment has also proved to be well tolerated, and hematological toxicity, in particular anemia, represents the most represented adverse event. Materials and methods: We evaluated the hematologic toxicity of Ra-223 treatment in a real-life experience of 38 patients from two Italian cancer centers, with bone metastases from mCRPC. The main endpoint of the study was the evaluation of the efficacy and tolerability of treatment with radium-223, with greater reference to hematological toxi…
Patterns of Bladder Preservation Therapy Utilization for Muscle-Invasive Bladder Cancer
2016
Background: Trimodality bladder preservation therapy (BPT) in muscle invasive bladder cancer (MIBC) includes a maximal transurethral resection followed by concurrent chemoradiotherapy as an alternative to radical cystectomy (RC) in appropriately selected patients, or as a treatment option in non-cystectomy candidates. Several chemotherapy regimens can be used in BPT, but little is known about current practice patterns. Objective: To describe utilization patterns of BPT and associated survival outcomes in MIBC. Methods: Data were collected from the Retrospective International Study of Cancers of the Urothelial Tract (RISC), a database of 3,024 consecutive patients from 29 international acade…
Evaluation of changes in salivary composition in renal failure patients before and after hemodialysis
2017
Background Saliva plays a major role in preserving the integrity of oral tissues. The oral health of renal failure patients could be negatively affected by the underlying pathology, the dialysis treatment, or an altered salivary composition. Major systemic changes occur during hemodialysis (HD), which could affect the flow rate and biochemical composition of saliva. Therefore, the aim of this study was to evaluate the effects of HD on the salivary flow rate, pH and biochemical composition before and after completion of a dialysis session. Material and methods Thirty Renal failure patients undergoing hemodialysis were selected based on the inclusion and exclusion criteria set forth for the s…