Search results for "neurocognition"
showing 10 items of 12 documents
Factors associated with poor functional outcome in bipolar disorder: sociodemographic, clinical, and neurocognitive variables.
2018
Objective: The current investigation aimed at studying the sociodemographic, clinical, and neuropsychological variables related to functional outcome in a sample of euthymic patients with bipolar disorder(BD) presenting moderate-severe levels of functional impairment. Methods: Two-hundred and thirty-nine participants with BD disorders and with Functioning Assessment Short Test(FAST) scores equal or above 18 were administered a clinical and diagnostic interview, and the administration of mood measure scales and a comprehensive neuropsychological battery. Analyses involved preliminary Pearson bivariate correlations to identify sociodemographic and clinical variables associated with the FAST t…
High cognitive reserve in bipolar disorders as a moderator of neurocognitive impairment
2017
BackgroundCognitive reserve (CR) reflects the capacity of the brain to endure neuropathology, minimize clinical manifestations and successfully complete cognitive tasks. The present study aims to determine whether high CR may constitute a moderator of cognitive functioning in bipolar disorder (BD).MethodsOne hundred and two patients with BD and 32 healthy controls were enrolled. All patients met DSM-IV criteria for I or II BD and were euthymic (YMRS ≤ 6 and HDRS ≤ 8) during a 6-month period. All participants were tested with a comprehensive neuropsychological battery, and a Cerebral Reserve Score (CRS) was estimated. Subjects with a CRS below the group median were classified as having low C…
Visual memory dysfunction as a neurocognitive endophenotype in bipolar disorder patients and their unaffected relatives. Evidence from a 5-year follo…
2019
BACKGROUND: Scarce research has focused on Visual Memory (VM) deficits as a possible neurocognitive endophenotype of bipolar disorder (BD). The main aim of this longitudinal, family study with healthy controls was to explore whether VM dysfunction represents a neurocognitive endophenotype of BD. METHODS: Assessment of VM by Rey-Osterrieth Complex Figure Test (ROCF) was carried out on a sample of 317 subjects, including 140 patients with BD, 60 unaffected first-degree relatives (BD-Rel), and 117 genetically-unrelated healthy controls (HC), on three occasions over a 5-year period (T1, T2, and T3). BD-Rel group scores were analyzed only at T1 and T2. RESULTS: Performance of BD patients was sig…
Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5…
2017
Background: Few studies have examined Manual Motor Speed (MMS) in bipolar disorder (BD). The aim of this longitudinal, family study was to explore whether dysfunctional MMS represents a neurocognitive endophenotype of BD. Methods: A sample of 291 subjects, including 131 BD patients, 77 healthy first-degree relatives (BD-Rel), and 83 genetically-unrelated healthy controls (HC), was assessed with the Finger-Tapping Test (En) on three occasions over a 5-year period. Dependence of FTT on participants' age was removed by means of a lineal model of HC samples, while correcting simultaneously the time and learning effect. Differences between groups were evaluated with an ANOVA test. Results: The p…
Education and long-term outcomes in first episode psychosis: 10-year follow-up study of the PAFIP cohort
2021
[Background] Lower levels of education have been associated with the development of psychosis. Investigating educational achievement in the first episode of psychosis (FEP) patients may shed light on the origins of the alterations and on the variability of outcomes in psychotic disorders.
Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use
2020
Abstract Psychotic patients with a lifetime history of cannabis use generally show better cognitive functioning than other psychotic patients. Some authors suggest that cannabis-using patients may have been less cognitively impaired and less socially withdrawn in their premorbid life. Using a dataset comprising 948 patients with first-episode psychosis (FEP) and 1313 population controls across 6 countries, we examined the extent to which IQ and both early academic (Academic Factor [AF]) and social adjustment (Social Factor [SF]) are related to the lifetime frequency of cannabis use in both patients and controls. We expected a higher IQ and a better premorbid social adjustment in psychotic p…
Teacher training paths between neuroeducation and professional learning community
2016
This paper starts from the belief that a school capable of feeling and making community is regarded as a privileged context to promote both organizational and relational well-being. Teacher training is possible in the intersection between the concepts of Neuroeducation and learning community. Moreover, the concept of "school-as-a-community" interacts with that of "peer learning", which is configured as a methodology capable of simultaneously promoting the ability of realization of the individual and of the organization. From a methodological point of view, this work documents a research project carried out with a group of 69 teachers of the first cycle of education. Moving from the problems…
Bipolar disorder comorbid with alcohol use disorder: focus on neurocognitive correlates
2015
Bipolar disorder (BD) and alcohol use disorders (AUDs) are usually comorbid, and both have been associated with significant neurocognitive impairment. Patients with the BD-AUD comorbidity (dual diagnosis) may have more severe neurocognitive deficits than those with a single diagnosis, but there is paucity of research in this area. To explore this hypothesis more thoroughly, we carried out a systematic literature review through January 2015. Eight studies have examined the effect of AUDs on the neurocognitive functioning of BD patients. Most studies found that BD patients with current or past history of comorbid AUDs show more severe impairments, especially in verbal memory and executive cog…
Funcionamiento neurocognitivo y psicosocial de pacientes con trastorno bipolar en una unidad de salud mental
2018
INTRODUCCION: Existe evidencia de que los pacientes que padecen Trastoro Bipolar (TB), e incluso sus familiares sanos, presentan patrones característicos de afectación de ciertos dominios neurocognitivos que persisten tras la remisión clínica o período de eutimia. La pérdida de funcionalidad psicosocial de estos pacientes se predice mejor con la presencia de alteraciones cognitivas que con variables clínicas o evolutivas. El clínico asistencial debería conocer si existe afectación o deterioro en las funciones neurocognitivas de sus pacientes pero en el medio asistencial cotidiano es difícil poder evaluar adecuadamente las funciones cognitivas y tampoco se acostumbra a cuantificar la funcion…
Relaciones entre neurocognición, procesamiento emocional y funcionamiento social en la esquizofrenia
2017
Resumen: En la esquizofrenia se presentan una serie de déficits cognitivos que han hecho que la investigación y la práctica profesional actual se centren en el estudio de la neurocognición y la cognición social. Estos déficits tienen importantes implicaciones en el funcionamiento social. El objetivo del presente trabajo es analizar la relaciones entre neurocognición, cognición social, evaluada con tareas de reconocimiento de la emoción, y funcionamiento social. Sesenta personas con diagnóstico de esquizofrenia han formado la muestra y las áreas evaluadas han sido: funcionamiento ejecutivo y flexibilidad cognitiva, atención y vigilancia, memoria, velocidad de procesamiento, identificación y …