Search results for "ngos"

showing 10 items of 115 documents

Data from: Very high MHC Class IIB diversity without spatial differentiation in the Mediterranean population of Greater Flamingos

2017

MHC Class II Genotype data Greater Flamingo MHC Class IIB genoptype data of four Mediterranean breeding colonies: France, Spain, Algeria and Turkey MHCClassIIGenotypeGreaterFlamingo.xlsx

medicine and health caregreater flamingosallelic diversityMedicineAllelic diversityMHC genesgreater flamingosGreater flamingosLife sciencesPathogen-mediated balancing selection
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Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity.

2019

The synthesis of inhibitors of SphK2 with novel structural scaffolds is reported. These compounds were designed from a molecular modeling study, in which the molecular interactions stabilizing the different complexes were taken into account. Particularly interesting is that 7‐bromo‐2‐(2‐phenylethyl)‐2,3,4,5‐tetrahydro‐1,4‐epoxynaphtho[1,2‐b]azepine, which is a selective inhibitor of SphK2, does not exert any cytotoxic effects and has a potent anti‐inflammatory effect. It was found to inhibit mononuclear cell adhesion to the dysfunctional endothelium with minimal impact on neutrophil–endothelial cell interactions. The information obtained from our theoretical and experimental study can be us…

medicine.drug_classCell SurvivalNeutrophilsFísico-Química Ciencia de los Polímeros ElectroquímicaCellAnti-Inflammatory AgentsPharmaceutical ScienceSYNTHESIS01 natural sciencesPeripheral blood mononuclear cellAnti-inflammatoryANTI-INFLAMMATORY ACTIVITYchemistry.chemical_compoundStructure-Activity RelationshipDrug DiscoverymedicineCell AdhesionHuman Umbilical Vein Endothelial CellsCytotoxic T cellHumansMOLECULAR MODELINGAzepineEnzyme Inhibitors010405 organic chemistryBIOASSAYSCiencias QuímicasSphingosine Kinase 2AdhesionAzepines0104 chemical sciencesMolecular Docking Simulation010404 medicinal & biomolecular chemistrySPHK2Phosphotransferases (Alcohol Group Acceptor)medicine.anatomical_structurechemistrySPHINGOSINE KINASE 2 INHIBITORSDrug DesignCancer researchEpoxy CompoundsEndothelium VascularCIENCIAS NATURALES Y EXACTASProtein BindingArchiv der Pharmazie
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Analysis and review of the perioperative management of COVID-19 patients in thoracic surgery.

2021

Resumen Debido a la grave situacion de pandemia que vivimos causada por el COVID-19, la Seccion de Anestesia Cardiaca, Vascular y Toracica de la SEDAR pretende dar informacion de los aspectos mas relevantes a considerar en pacientes con sospecha o infeccion confirmada por coronavirus que van a ser sometidos a cirugia toracica. Creemos que es esencial mantener una optima transmision de informacion para llevar a cabo maniobras seguras, tanto para los pacientes como para el personal sanitario. La estrategia de manejo debe basarse en una organizacion exquisita del trabajo, definiendo quien, como y cuando va a realizar cada tarea y procedimiento. Las recomendaciones que se proponen, tras valorar…

medicine.medical_specialty2019-20 coronavirus outbreakThoracic Surgical Procedureone-lung ventilationCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEcirugía torácica030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineArticlePerioperative Care03 medical and health sciencesmanejo de vía aérea0302 clinical medicinelung isolation/separationBronchoscopyIntubation Intratrachealventilation unipulmonarMedicineHumansAnesthesiaairway managementPerioperative managementCirurgiaLaryngoscopybusiness.industryGeneral surgeryAnestèsiaaislamiento/separación pulmonarCOVID-19General MedicineLetter to the DirectorThoracic Surgical Proceduresthoracic surgeryAnesthesiology and Pain Medicine030228 respiratory systemCardiothoracic surgeryPerioperative carePractice Guidelines as TopicAirway ExtubationbusinessHumanitiesRevista espanola de anestesiologia y reanimacion
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2017

IntroductionThe direct laryngoscopy technique using a Macintosh blade is the first choice globally for most anaesthetists. In case of an unanticipated difficult airway, the complication rate increases with the number of intubation attempts. Recently, McGrath MAC (McGrath) video laryngoscopy has become a widely accepted method for securing an airway by tracheal intubation because it allows the visualisation of the glottis without a direct line of sight. Several studies and case reports have highlighted the benefit of the video laryngoscope in the visualisation of the glottis and found it to be superior in difficult intubation situations. The aim of this study was to compare the first-pass in…

medicine.medical_specialtyGlottismedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentTracheal intubationLaryngoscopy030208 emergency & critical care medicineGeneral Medicinelaw.inventionSurgery03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureRandomized controlled triallawmedicineIntubationAirway managementGeneral anaesthesia030212 general & internal medicineAirwaybusinessBMJ Open
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Disposable chlorine dioxide wipes for high-level disinfection in the ENT department: A systematic review

2020

Abstract Background Nasopharyngoscope reprocessing methods should be effective, rapid and reproducible with moderate cost. Tristel Trio Wipes system (TTWS) is a manual reprocessing method based on chlorine dioxide that has lately emerged in ENT department. This review aims to collect evidence on this system. Methods The PubMed, Web of Science and Cochrane Library databases were searched for all the studies on TTWS or one of its components. Data were grouped according to the study type. Results Ten articles were included in the review. TTWS ensured high-level disinfection in laboratory and clinical setting. Although the limitations of the manual systems, TTWS proved to be faster than automat…

medicine.medical_specialtyHigh-level disinfection (HLD)NasopharyngoscopeWeb of scienceChlorine compoundHospital DepartmentsNasopharyngoscopesCochrane LibraryLaryngoscopesChlorine dioxideChlorine compounds; Chlorine dioxide; Decontamination; Disinfection; Endoscopes; High-level disinfection (HLD); Laryngoscopes; Nasopharyngoscopes; Otolaryngology; Reprocessing03 medical and health scienceschemistry.chemical_compoundOtolaryngology0302 clinical medicineLaryngoscopesEndoscopemedicine030223 otorhinolaryngologyDecontaminationEndoscopesChlorine dioxidebusiness.industryStudy TypeENT departmentOxidesmedicine.diseaseDisinfectionReprocessingNasopharyngoscopesOtorhinolaryngologyOtorhinolaryngologychemistry030220 oncology & carcinogenesisLaryngoscopeEquipment ContaminationMedical emergencybusinessChlorine Compounds
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Refractory Death Rattle: Deep Aspiration Facilitates the Effects of Antisecretory Agents

2011

Anticholinergic drugs, including atropine, hyoscine butylbromide, and scopolamine, have been shown to be equally effective in the treatment of death rattle. However, anticholinergic drugs may only be effective in reducing the production of further secretions, rather than eliminating the existing ones. A case is described in which a preventive procedure was undertaken to carefully eliminate secretions before starting anticholinergic drugs. Airway aspiration under light anesthesia removed secretions before starting anticholinergic drugs. Low doses of propofol were given intravenously to make a laryngoscopy feasible, allowing the complete aspiration of large amounts of tracheal secretions. No …

medicine.medical_specialtyLung NeoplasmsLaryngoscopyPainCholinergic AntagonistsFatal OutcomeRefractoryIntervention (counseling)Administration InhalationmedicineHumansDeath rattleIntensive care medicineGeneral NursingAgedRespiratory SoundsRetrospective StudiesTerminal Caremedicine.diagnostic_testbusiness.industryAntisecretory agentsPharyngeal DiseasesDeathAtropineDyspneaAnesthesiology and Pain MedicineAnesthesiaRespiratory MechanicsFemaleNeurology (clinical)medicine.symptomPropofolbusinessAirwaymedicine.drugJournal of Pain and Symptom Management
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Efficacy and Safety of Using High-Flow Nasal Oxygenation in Patients Undergoing Rapid Sequence Intubation

2017

Objective To assess the efficacy and safety of high-flow nasal oxygen (HFNO) therapy in patients undergoing rapid sequence intubation (RSI) for emergency abdominal surgery. Methods HFNO of 60 L.min-1 at an inspiratory oxygen fraction of 1 was delivered 4 min before laryngoscopy and maintained until the patient was intubated, and correct intubation was verified by the appearance of the end-tidal CO2 (EtCO2) waveform. Transcutaneous oxygenation (SpO2), heart rate and non-invasive mean arterial pressure were monitored at baseline (T0), after 4 min on HFNO (T1) and at the time of laryngoscopy (T2) and endotracheal intubation (ETI) (T3). An SpO2 of <3% from baseline was recorded at any sampled t…

medicine.medical_specialtyMean arterial pressuremedicine.medical_treatmentLaryngoscopyHigh-flow nasal oxygen therapy; Pre-oxygenation; Rapid sequence intubation; Emergency Medicine; Anesthesiology and Pain MedicineHigh-flow nasal oxygen therapy03 medical and health sciences0302 clinical medicine030202 anesthesiologyInterquartile rangeRapid sequence intubationmedicineIntubationGeneral anaesthesiaRocuroniummedicine.diagnostic_testbusiness.industryRapid sequence inductionSurgeryPre-oxygenationAnesthesiology and Pain Medicine030228 respiratory systemAnesthesiaEmergency MedicineOriginal ArticlePropofolbusinessmedicine.drugTurkish Journal of Anesthesia and Reanimation
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Value of Neurostimulation Plus Laryngeal Palpation to Predict Postoperative Vocal Fold Motility.

2021

ABSTRACT Background The aim of this study was to evaluate the reliability of intraoperative neuromonitoring through recurrent laryngeal nerve stimulation and simultaneous laryngeal palpation (NSLP) in predicting postoperative vocal cord palsy and in providing useful information in the decision to perform a staged surgery in initially planned total thyroidectomy. Materials and Methods A retrospective review was performed involving 552 patients for whom a total thyroidectomy was planned. In all patients, preoperative and postoperative laryngoscopy was performed. The incidence of vocal cord palsy was calculated on 1104 nerves at risk. Results Sensitivity and specificity of NSLP were 0.9411 and…

medicine.medical_specialtyNerve injurymedicine.medical_treatmentLaryngoscopyIntraoperative nerve monitoringVocal CordsPalpationThyroid carcinomamedicineRecurrent laryngeal nerveHumansNeurostimulationRetrospective StudiesLaryngeal palpationPalpationmedicine.diagnostic_testbusiness.industryRecurrent Laryngeal NerveThyroid diseaseThyroidectomyReproducibility of Resultsmedicine.diseaseSurgeryRecurrent Laryngeal Nerve InjuriesThyroidectomySurgeryFalse positive ratebusinessVocal Cord ParalysisThe Journal of surgical research
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2017

Purpose It is generally accepted that using a video laryngoscope is associated with an improved visualization of the glottis. However, correctly placing the endotracheal tube might be challenging. Channeled video laryngoscopic blades have an endotracheal tube already pre-loaded, allowing to advance the tube once the glottis is visualized. We hypothesized that use of a channel blade with pre-loaded endotracheal tube results in a faster intubation, compared to a curved Macintosh blade video laryngoscope. Methods After ethical approval and informed consent, patients were randomized to receive endotracheal Intubation with either the King Vision® video laryngoscope with curved blade (control) or…

medicine.medical_specialtyanimal structuresMultidisciplinaryGlottisBlade (geometry)business.industrymedicine.medical_treatmentTracheal intubationVideo laryngoscopefood and beverages030208 emergency & critical care medicineEndotracheal intubationSurgery03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurestomatognathic system030202 anesthesiologymedicineIntubationTrial registrationbusinessEndotracheal tubePLOS ONE
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Video laryngoscopy vs. direct laryngoscopy – Influence of the training status on the performance in both settings: An interim evaluation of a prospec…

2017

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryLaryngoscopyCritical Care and Intensive Care Medicinelaw.inventionAnesthesiology and Pain MedicineVideo laryngoscopyRandomized controlled triallawInterimmedicinePhysical therapyIntensive care medicinebusinessTrends in Anaesthesia and Critical Care
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