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showing 10 items of 114 documents
Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists.
2013
p38 Mitogen-activated protein (MAP) kinase is involved in the apoptosis of nucleated cells. Although platelets are anucleated cells, apoptotic proteins have been shown to regulate platelet lifespan. However, the involvement of p38 MAP kinase in platelet apoptosis is not yet clearly defined. Therefore, we investigated the role of p38 MAP kinase in apoptosis induced by a mimetic of BH3-only proteins, ABT-737, and in apoptosis-like events induced by such strong platelet agonists as thrombin in combination with convulxin (Thr/Cvx), both of which result in p38 MAP kinase phosphorylation and activation. A p38 inhibitor (SB202190) inhibited the apoptotic events induced by ABT-737 but did not influ…
Regulatory activity of human CD4 CD25 T cells depends on allergen concentration, type of allergen and atopy status of the donor.
2005
Regulatory CD4+ CD25+ FoxP3-positive T cells (Treg) are functional in most atopic patients with allergic rhinitis and are able to inhibit T helper type 1 (Th1) and Th2 cytokine production of CD4+ CD25- T cells. This study was designed to analyse the following additional aspects: influence of allergen concentration, influence of the type of allergen, and influence of the atopy status of the donor on the strength of the regulatory activity. CD4+ CD25- T cells from healthy non-atopic controls or from grass-pollen-allergic or wasp-venom-allergic donors were stimulated alone or in the presence of Treg with autologous mature monocyte-derived dendritic cells which were pulsed with different concen…
La recepció dels postulats de la filologia romànica internacional sobre la llengua catalana en el conjunt de la catalanofonia (1854-1906)
2020
Aquest treball analitza la recepció dels postulats de la filologia romànica in - ternacional sobre l'origen, la identitat i el nom de la llengua catalana en el conjunt de la catalanofonia entre 1854 i 1906. Al segle XIX es situa l'inici de la filologia romànica, i cada vegada més erudits cataloguen i estudien les diferents llengües romàniques. Progressivament, en aquest període els romanistes prenen en consideració la llengua catalana, i realitzen afirmacions sobre el seu origen -compartit amb la llengua occitana o independent des de l'inici-, la seua identitat -subordinada a l'occità o autònoma com la resta de llengües romàniques- i el nom amb què cal referir-s'hi. L'objectiu d'aquesta inv…
Barcelona i la moda toponímica
2018
Un famós manual de dialectologia catalana descriu el sobrenom Barceló com «masculinització de Barcelona», donant aixina més antigor a la forma toponímica.
Macrotopònims Ibèrics en Catalunya
2018
En els darrers anys dos candents qüestions colaterals han in primis afectat a la llengua ibèrica: la seua Urheimat o més antic territori original en la Península Ibèrica i sa relació en el continuum llingüístic valencià-català.
La posició dels romanistes italians i algueresos sobre el català al segle XIX
2016
In the middle of the 19th century the German romanists found the Romance philology. They established that Catalan is the name of a language of the Catalan-speaking areas, which is different from Occitan and which has nothing to do with Limousin, something known since the early 16th century. This paper analyzes the opinion of Italian romanists about the name, beginning and identity of the Catalan language between 1808 and 1906.
Llobell: un sobrenom valencià
2021
Com és sabut, el nom del "llop" ha generat directament o indirecta multitut d'antropònims en no poques llengües (anglés Wolf, espanyol López, gòtic Wulfila, llatí Vlpius, polac Wilk, serp-croat Vuk, vasc Otxoa...). El valencià dispon del sobrenom o llinage Llop (del llatí lupu-) i també d'una forma que podem considerar pròpia: el diminutiu Llobell. Segons els data per a 2017 del padró de l'Institut Nacional d'Estadística, 916 espanyols porten Llobell com a primer llinage, la majoria dels quals han naixcut en les tres províncies valencianes, sobretot en Alacant (517 individus i una proporció de 0,432 ), seguida de Valéncia (236 - 0,119) i Castelló (8 - 0,019). Tenim també una variant gràfica…
El nom de la llengua als territoris de parla catalana entre 1854 i 1906
2020
This paper analyses the names that Catalan-Speaking writers and scholars were using to refer the Catalan language between 1854 and 1906. These used mainly the names 'llemosí' and 'català', but the second displaces the first at a different rate in the different Catalan Countries. The withdrawal of the 'llemosí' begins in Northern Catalonia and spreads first in Catalonia ¿since 1854¿ and later in the Balearic Islands and Valencian Country.
The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes
2015
The mucus produced by many marine organisms is a complex mixture of proteins and polysaccharides forming a weak watery gel. It is essential for vital processes including locomotion, navigation, structural support, heterotrophic feeding and defence against a multitude of environmental stresses, predators, parasites, and pathogens. In the present study we focused on mucus produced by a benthic cnidarian, the sea anemone Actinia equina (Linnaeus, 1758) for preventing burial by excess sedimentation and for protection. We investigated some of the physico-chemical properties of this matrix such as viscosity, osmolarity, electrical conductivity, protein, carbohydrate, and total lipid contents. Som…
Old Weapons for New Wars: Bioactive Molecules From Cnidarian Internal Defense Systems
2016
The renewed interest in the study of genes of immunity in Cnidaria has led to additional information to the scenario of the first stages of immunity evolution revealing the cellular processes involved in symbiosis, in the regulation of homeostasis and in the fight against infections. The recent study with new molecular and functional approach on these organisms have therefore contributed with unexpected information on the knowledge of the stages of capturing activities and defense mechanisms strongly associated with toxin production. Cnidarians are diblastic aquatic animals with radial symmetry; they represent the ancestral state of Metazoa, they are the simplest multicellular organisms tha…