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showing 10 items of 1921 documents

Direct involvement of acid centers of polyaniline in charge transfer on organic acceptor

1996

Abstract Electrochemical behavior of hydroquinone and 4F-hydroquinone has been studied on Pt/polyaniline (PANI) electrodes in 1 M H 2 SO 4 solution. Redox transformation of quinone/hydroquinone systems takes place on PANI practically without overpotential and, probably, the two-electron charge transfer processes are realized in such systems. Reaction currents depend on PANI quantities deposited on the Pt electrode and the molecular complex is formed. There exists a great electronic exchange between acid centers of PANI and quinone/hydroquinone molecules, resulting in electronic conjugation of this surface state (adsorbed molecule) with the polymer. Existence of such complexes was confirmed …

HydroquinoneMechanical EngineeringInorganic chemistryMetals and AlloysOverpotentialCondensed Matter PhysicsElectrochemistryAcceptorRedoxElectronic Optical and Magnetic MaterialsQuinonechemistry.chemical_compoundchemistryMechanics of MaterialsPolyanilineMaterials ChemistryMoleculeSynthetic Metals
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Molecular orbital study of conformational isomers and rotational barriers of methyl substituted hydroquinone cation radicals

1998

Abstract The torsional potential energy curve of the hydroxyl group of hydroquinone and tetramethyl-hydroquinone cation radicals were explored with various ab initio methods. The minimum and the torsional transition state geometries and energies were computed by using high accuracy density functional methods yielding the rotation barrier height and the energy difference between the cis- and trans-isomers. The obtained minimum energy geometry for the hydroquinone cation radical indicates that the CO bond has shortened when compared to the neutral species. We attribute this to the increased double-bond character of this bond. The energy minima were located for methyl-hydroquinone, 2,3-dimeth…

HydroquinoneRadicalAb initioCondensed Matter PhysicsBiochemistryBoltzmann distributionchemistry.chemical_compoundchemistryComputational chemistryPhysical chemistryMolecular orbitalPhysical and Theoretical ChemistryTorsional potentialConformational isomerismCis–trans isomerismJournal of Molecular Structure: THEOCHEM
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Arylated phenols, aroxyl radicals and aryloxenium ions syntheses and properties

1985

Hydroxylationchemistry.chemical_compoundPyrylium saltchemistryRadicalOrganic chemistryDehydrogenationPhenolsElectrophilic aromatic substitutionQuinoneIon
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C3-Symmetric Ligands for Catalysis

2008

Hydroxylationchemistry.chemical_compoundchemistryCyclohexanoneOrganic chemistryCatalysis
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Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo…

2002

Abstract Chinese hamster lung fibroblasts, genetically engineered for the expression of rat cytochrome P450 dependent monooxygenase 1A2 and rat sulfotransferase 1C1 (V79-rCYP1A2-rSULT1C1 cells), were utilized to check for possible protective effects of beverages of plant origin, fruits, vegetables, and spices against genotoxicity induced by 2-acetylaminofluorene (AAF) or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Antigenotoxic activities of juices from spinach and red beets against AAF could be monitored with similar effectivity by the HPRT-mutagenicity test (IC50=0.64%; 2.57%) and alkaline single cell gel electrophoresis (comet assay; IC50=0.12%; 0.89%) which detects DNA stran…

Hypoxanthine PhosphoribosyltransferaseHealth Toxicology and Mutagenesismedicine.disease_causeCell LineBeverageschemistry.chemical_compoundCricetulusCytochrome P-450 CYP1A2CricetinaeVegetablesGeneticsmedicineAnimalsWineFlavonoids2-Amino-1-methyl-6-phenylimidazo(45-b)pyridinePlants MedicinalbiologyMutagenicity TestsImidazolesfood and beveragesAntimutagenic AgentsMonooxygenase2-AcetylaminofluoreneFibroblastsbiology.organism_classificationRecombinant ProteinsRatsComet assayBiochemistrychemistryWhite WineFruitFlavanonesSpinachQuercetin2-AcetylaminofluoreneComet AssaySulfotransferasesGenotoxicityMutagensMutation research
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De Kosala a Bollywood: dos mil años contando historias. Un estudio semiótico del ramayana

2008

El Rāmāyaa se originó en el norte de la India entre los siglos IV a.C. y IV d.C. Contiene elementos fantásticos, míticos, legendarios y religiosos. Los jainistas y los budistas escribieron sus propios rāmāyaas para criticar aspectos del brahmanismo y difundir sus doctrinas. La literatura sánscrita se inspiró en la leyenda de Rāma y la historia también se incluyó en los purāas. En el siglo V aparecieron las primeras narrativas visuales, paneles esculpidos en los templos que se leen como secuencias cinematográficas. La devoción y el culto a Rāma se popularizaron con el movimiento devocional (bhakti) y se compusieron rāmāya&#…

INSTITUT DE LA DONAnone80
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Dažu ivabradīna sintēzes stadiju pētījumi

2018

Dažu ivabradīna sintēzes stadiju pētīšana. Lugovskojs R., zinātniskie vadītāji MSc. Reine I. un Dr. chem. doc. Kļimenkovs I. Bakalaura darbs, 36 lappuses, 25 attēli, 3 tabulas, 24 literatūras avoti. Latviešu valodā. Darbā ir pētītas triju svarīgo ivabradīna starpproduktu - 7,8-dimetoksi-1H-benzo[d]azepin-2(3H)-ona, 3-(3-hlorpropil)-7,8-dimetoksi-1H-dihidro-2H-3-benzo[d]azepin-2(3H)-ona un dehidroivabradīna iegūšanas metodes ar mērķi atrast optimālus reakcijas apstākļus, kas piemēroti sintēzes veikšanai rūpnieciskā mērogā. Darbā ir apkopota pieejamā literatūra par ivabradīna un tā svarīgāko starpproduktu iegūšanas metodēm. Īpaši ir pētīta 7,8-dimetoksi-1H-benzo[d]azepin-2(3H)-ona alkilēšana,…

IVABRADINECYCLISATIONBENZAZEPINONESCALE-UPALKYLATIONĶīmija
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Inhibition of imidazolidinone intermediate formation in the aldol reactions catalyzed by zinc–prolinamide complexes

2011

Abstract The use of zinc salts as cocatalysts in aldol condensations catalyzed by single prolinamide (and in the extension by other more complex prolinamides) can prevent the formation of the parasitic intermediate imidazolidinone, with faster and also more stereoselective reactions than those catalyzed by the free amine. This new finding, together with this ion’s already known properties, make zinc salts highly suitable additives for aldol reactions catalyzed for prolinamide derivatives.

ImidazolidinoneOrganic Chemistrychemistry.chemical_elementZinc saltsZincBiochemistryCombinatorial chemistryCatalysischemistry.chemical_compoundchemistryAldol reactionDrug DiscoveryTrifluoroacetic acidOrganic chemistryStereoselectivityAmine gas treatingTetrahedron
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In silico methods for metabolomic and toxicity prediction of zearalenone, α-zearalenone and β-zearalenone.

2020

Zearalenone (ZEA), α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL) (ZEA's metabolites) are co/present in cereals, fruits or their products. All three with other compounds, constitute a cocktail-mixture that consumers (and also animals) are exposed and never entirely evaluated, nor in vitro nor in vivo. Effect of ZEA has been correlated to endocrine disruptor alterations as well as its metabolites (α-ZEL and β-ZEL); however, toxic effects associated to metabolites generated once ingested are unknown and difficult to study. The present study defines the metabolomics profile of all three mycotoxins (ZEA, α-ZEL and β-ZEL) and explores the prediction of their toxic effects proposing an in silico w…

In silicoMetaboliteToxicologyArticleAmes test03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyMetabolomicsGlucuronidesCytochrome P-450 Enzyme SystemIn vivoAnimalsMetabolomicsComputer SimulationMycotoxinZearalenoneZebrafish030304 developmental biology0303 health sciencesChemistryIn silicofood and beverages04 agricultural and veterinary sciencesGeneral Medicine040401 food sciencePASS onlineEndocrine disruptorBiochemistryBlood-Brain BarrierMetaToxZearalenoneSwissADMEReactive Oxygen SpeciesPredictionFood ScienceFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
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NQS-Doped PDMS Solid Sensor: From Water Matrix to Urine Enzymatic Application

2021

The development of in situ analytical devices has gained outstanding scientific interest. A solid sensing membrane composed of 1,2-naphthoquinone-4-sulfonate (NQS) derivatizing reagent embedded into a polymeric polydimethylsiloxane (PDMS) composite was proposed for in situ ammonium (NH4+) and urea (NH2CONH2) analysis in water and urine samples, respectively. Satisfactory strategies were also applied for urease-catalyzed hydrolysis of urea, either in solution or glass-supported urease immobilization. Using diffuse reflectance measurements combined with digital image processing of color intensity (RGB coordinates), qualitative and quantitative analyte detection was assessed after the colorime…

In situAnalyteMaterials scienceUreasePolymersClinical BiochemistrywaterNQS02 engineering and technologyureaurea hydrolysis01 natural sciencesArticlechemistry.chemical_compoundDimethylpolysiloxanesoptical sensorureaseglass supportChromatographyPolydimethylsiloxanebiology010405 organic chemistryGeneral Medicine021001 nanoscience & nanotechnologyurine0104 chemical sciencesin-situ analysisammoniumMembranechemistryReagentUreabiology.proteinColorimetry0210 nano-technologyTP248.13-248.65NaphthoquinonesNQS-PDMS sensorBiotechnologyBiosensors
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