Search results for "nuclear chemistry"

showing 10 items of 1124 documents

Mucoadhesive Polymer Hyaluronan as Biodegradable Cationic/Zwitterionic-Drug Delivery Vehicle

2014

Mucoadhesive polymers in pharmaceutical formulations release drugs in mucosal areas. They interact and fix to mucus via molecular interpenetration, etc ., which increase drug bioavailability. Polymers physicochemical properties affect formulation mucoadhesion, rheological behaviour and drug absorption. Hyaluronan (HA) is selected as a mucoadhesive and biodegradable polymer. Geometric, topological and fractal analyses are carried out with program TOPO. Reference calculations are performed with algorithm GEPOL. Procedure TOPO underestimates molecular volume by 0.7%. Error results 5% in surface area and derived topological indices. Solvent-accessible surface is undercalculated by 3%: from hexa…

chemistry.chemical_classificationAbsorption (pharmacology)Chemistrylcsh:RM1-950Cationic polymerizationMedicine (miscellaneous)NanotechnologyPolymerBiodegradable polymerBioavailabilitymedicine absorption; medicine delivery; dipole moment; fractal dimension; metal hyaluronate; mucosalcsh:Therapeutics. PharmacologyChemistry (miscellaneous)Drug deliveryMucoadhesionPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsHydrateNuclear chemistryADMET and DMPK
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Immobilization of vegetable tannins on tannery chrome shavings and their use for the removal of hexavalent chromium from contaminated water

2011

Abstract Chestnut (C) and mimosa (M) tannins immobilized on chrome shavings (CS) as an adsorbent have been proposed to be an efficient and economical alternative in hexavalent chromium removal from aqueous solutions. The adsorption of hexavalent chromium onto chrome shavings-tannin (CS-T) adsorbents was performed using batch equilibrium technique at 25 ± 2 °C. The effect of pH is highly important especially in the case of high concentrations of hexavalent chromium. The maximum chromium uptake was obtained at pH 4. Two hours of contact time are enough to reach equilibrium. Sorption of chromium on CS-T was found to follow a pseudo-second order kinetic model (with correlation coefficients grea…

chemistry.chemical_classificationAqueous solutionChemistryGeneral Chemical EngineeringMetallurgyLangmuir adsorption modelchemistry.chemical_elementSorptionGeneral ChemistryIndustrial and Manufacturing Engineeringsymbols.namesakechemistry.chemical_compoundChromiumAdsorptionPolyphenolsymbolsEnvironmental ChemistryTanninHexavalent chromiumNuclear chemistryChemical Engineering Journal
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Wirkung der Insektizide Allethrin, Lindan und Jacutin-Fogetten-Sublimat auf den photosynthetischen Elektronentransport

1977

Summary During our studies of Hill-reactions of isolated chloroplasts we observed an inhibition of electron transport after an application of the smoke of «Jacutine-Fogetten» in the plant growth chamber. Therefore we tested the influence of the insecticides Lindane (Gammexan), the sublimate formed by the fumigation of «Jacutin Fogetten», and of Allethrin on the photosynthetic electron transport reactions of PS II and PS I. 39 μ M Lindane inhibits the basal, coupled and uncoupled electron transport to ferricyanide of broken chloroplasts isolated from leaves of Pisum sativum up to 35%. A higher inhibitory effect with higher concentrations is limited by the low water solubility of Lindane. On …

chemistry.chemical_classificationAqueous solutionStereochemistryGeneral MedicineElectron acceptorPhotosynthesisElectron transport chainBenzoquinonechemistry.chemical_compoundchemistryFerricyanideDichlorophenolindophenolLindaneNuclear chemistryZeitschrift für Pflanzenphysiologie
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Studies of the ternary systems humic substances – kaolinite – Pu(III) and Pu(IV)

2008

AbstractThe behaviour of plutonium with respect to its migration in the aquifer has been studied under conditions close to nature. Most relevant under these conditions are Pu(III) and Pu(IV) in contact with humic substances (HS) and minerals. As a model for the host rock, kaolinite (KGa-1b) was chosen. The complexation of Pu(III) and Pu(IV) with Aldrich humic acid (AHA) in aqueous solution at ionic strength 0.1 M was investigated by the ultrafiltration method. The sorption of Pu(III) and Am(III) onto kaolinite (K) as a function of pH and metal-ion concentration was studied under aerobic and anaerobic conditions. The pH edge was found at pH∼5.5 independent of the metal-ion concentration and …

chemistry.chemical_classificationAqueous solutionTernary numeral systemchemistryIonic strengthInorganic chemistryUltrafiltrationHumic acidKaoliniteSorptionPhysical and Theoretical ChemistryTernary operationNuclear chemistryRadiochimica Acta
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Mathematic predictive models for calculating copper, iron and zinc dialysability in infant formulas

2001

Differences in the dialysability of a mineral element from infant formulas of the same type were detected in a previous study. As these may be due to the effects that different levels of the components of the formulas could have on dialysability, we attempted to establish mathematical models to predict the dialysability of Cu, Fe and Zn from infant formulas according to their ascorbic, citric, or selected amino acid contents. A simple linear regression was applied between the ascorbic acid, citric acid and amino acid contents and the Cu, Fe and Zn dialysability of 18 powdered infant formulas of different types. Significant correlations (P<0.05) were obtained between the dialysability of Fe …

chemistry.chemical_classificationArginineChemistryInorganic chemistryLysinechemistry.chemical_elementGeneral ChemistryZincAscorbic acidBiochemistryIndustrial and Manufacturing EngineeringAmino acidchemistry.chemical_compoundGlycineCitric acidFood ScienceBiotechnologyCysteineNuclear chemistry
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Elektrocarboxylierung organischer Chloride mit Zehrandon

1984

Carboxylation par CO 2 de chloro-1 propane, -butane, α-chlorotoluene, dichlorobenzene, chloro-1 naphtalene et chloro-1p ethylbenzene en presence d'une anode de Al dans DMF-bromure de tetrabutylammonium

chemistry.chemical_classificationBicyclic moleculeCarboxylic acidchemistry.chemical_elementGeneral MedicineElectrochemistryButyric acidchemistry.chemical_compoundchemistryCarboxylationAluminiumCarboxylateAliphatic compoundNuclear chemistryAngewandte Chemie
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Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

2019

Cerium oxide nanoparticles (CeNPs) have been shown to exhibit antioxidant capabilities, but their efficiency in scavenging reactive oxygen species (ROS) and the underlying mechanisms are not yet well understood. In this study, cerium dioxide nanoparticles (CeNPs) and nanorods (CeNRs) were found to exhibit much stronger scavenging activity than ·OH generation in phosphate buffered saline (PBS) and surrogate lung fluid (SLF). The larger surface area and higher defect density of CeNRs may lead to higher ·OH scavenging activity than for CeNPs. These insights are important to understand the redox activity of cerium nanomaterials and provide clues to the role of CeNPs in biological and environmen…

chemistry.chemical_classificationCerium oxideReactive oxygen speciesAntioxidantGeneral Chemical EngineeringRadicalmedicine.medical_treatmentNanoparticlechemistry.chemical_elementmacromolecular substances02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesNanomaterialsCeriumchemistrymedicine0210 nano-technologyScavengingNuclear chemistryRSC Advances
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Stabilization of polynuclear plutonium(IV) species by humic acid

2014

Abstract Although the formation of tetravalent plutonium (Pu(IV)) polymers with natural organic matter was previously observed by spectroscopy, there is no quantitative evidence of such reaction in batch experiments. In the present study, Pu(IV) interaction with humic acid (HA) was investigated at pH 1.8, 2.5 and 3, as a function of HA concentration and for Pu total concentration equal to 6 × 10−8 M. The finally measured Pu(IV) concentrations ([Pu(IV)]eq) are below Pu(IV) solubility limit. Pu(IV)–HA interaction can be explained by the complexation of Pu(IV) monomers by HA up to [Pu(IV)]eq ∼ 10−8 M. However, the slope of the log–log Pu(IV)–HA binding isotherm changes from ∼0.7 to ∼3.5 for hi…

chemistry.chemical_classificationChemistrychemistry.chemical_elementPlutoniumchemistry.chemical_compoundHydrolysisMonomerTetramerGeochemistry and PetrologyHumic acidSolubilitySpectroscopyStoichiometryNuclear chemistryGeochimica et Cosmochimica Acta
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Spectrophotometric Determination of Cystine with O-Phthalaldehyde in the Absence of Thiol

1988

Abstract A spectrophotometric method for the determination of cystine with o-phthalaldehyde (OPA) in the absence of thiol is described. When cystine is heated at 60[ddot]C for 30 min in a low excess of OPA (pH 9.5), a very stable derivative with 1:2 stoichiometry (cystine:OPA) and an absorption maximum at 335 nm (E = 4600) is formed. At pH < 1 the derivative is protonated (protonation constants: log K1 = 5.88 and log K2 = 3.70 at I = 0.1 and 20[ddot]C) and another absorption band at 440 nm (E = 3800) appears, which allows the determination of cystine in the presence of other amino acids.

chemistry.chemical_classificationChromatographyBiochemistry (medical)Clinical BiochemistryCystineProtonationBiochemistryAnalytical ChemistryAmino acidchemistry.chemical_compoundO-PhthalaldehydechemistryElectrochemistryThiolAbsorption (chemistry)SpectroscopyDerivative (chemistry)StoichiometryNuclear chemistryAnalytical Letters
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Biocompatible polymeric micelles with polysorbate 80 for use in brain targeting.

2008

In this paper, the synthesis and characterization of novel amphiphilic graft copolymers based on an alpha,beta-poly(N-2-hydroxyethyl)-D, L-aspartamide (PHEA) backbone and D, L-polylactic acid (PLA) hydrophobic side chains are reported. These copolymers were obtained starting from PHEA-ethylenediamine (PHEA-EDA), which was functionalized with polysorbate 80 (PS(80)) and/or PLA in order to obtain the PHEA-EDA-PS(80)-PLA and PHEA-EDA-PLA samples, respectively. The degrees of derivatization, DD(PS80) and DD(PLA), of PHEA-EDA-PS80-PLA, calculated by (1)H-NMR, resulted in being 1.2 +/- 0.03 mol% and 0.54 +/- 0.05 mol%, respectively, while that of PHEA-EDA-PLA was found to be 0.60 +/- 0.05 mol%. S…

chemistry.chemical_classificationChromatographyMaterials scienceMechanical EngineeringSize-exclusion chromatographyBioengineeringGeneral ChemistryPolymerMicelleAMPHIPHILIC COPOLYMERS MICELLES BRAIN TARGETING POLYSORBATE 80chemistry.chemical_compoundchemistryMechanics of MaterialsSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoAmphiphileSide chainZeta potentialCopolymerGeneral Materials ScienceElectrical and Electronic EngineeringDerivatizationNuclear chemistryNanotechnology
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