Search results for "nucleus"
showing 10 items of 1803 documents
Charged-current neutrino-nucleus scattering off Xe isotopes
2019
Xenon detectors are used in the search for dark matter and neutrinoless double-beta decay ($0\ensuremath{\nu}\ensuremath{\beta}\ensuremath{\beta})$. As the next-generation detectors reach masses in the ton scale, neutrinos from astrophysical sources are soon predicted to become background in such detectors. Theoretical predictions of neutrino scattering cross sections and information of nuclear structure effects therein are crucial in accounting for the background. We perform calculations for differential and total cross sections of charged-current neutrino scattering off the most abundant xenon isotopes. The nuclear-structure calculations are made in the proton-neutron quasiparticle random…
Occupation probabilities of single particle levels using the microscopic interacting boson model: Application to some nuclei of interest in neutrinol…
2016
We have developed a new method to calculate the occupancies of single particle levels in atomic nuclei. This method has been developed in the context of the microscopic interacting boson model, in which neutron and proton degrees of freedom are treated explicitly. The energies of the single particle levels constitute a very important input for the calculation of the occupancies in this method. In principle these energies can be considered as input parameters that can be fitted to reproduce the experimental occupancies. Instead of fitting, in this study we have extracted the single particle energies from experimental data on nuclei with a particle more or one particle less than a shell closu…
Calculated solar-neutrino capture rate for a radiochemical 205Tl-based solar-neutrino detector
2020
Radiochemical experiments for low-energy solar-neutrino detection have been making headlines by exploiting the isotopes 37Cl and 71Ga. Such a very low-threshold measurement of this type can also be performed using 205Tl, which has been considered for decades for this purpose. A unique feature of this detector nucleus is the integration in the solar-neutrino flux over 106 of years owing to its long-living daughter 205Pb. In this Rapid Communication, we have calculated for the first time the cross section for the charged-current solar-neutrino scattering off 205Tl. Taking into account the solar-model-predicted neutrino fluxes and the electron-neutrino survival probabilities, a solar-neutrino …
Proliferation-associated oxygen consumption and morphology of tumor cells in monolayer and spheroid culture.
1992
The oxygen consumption rate, proliferative activity, and morphology of EMT6/Ro mouse mammary sarcoma cells in monolayer and multicellular spheroid culture have been investigated in a comparative study. During the transition of monolayer cells from the exponential into the plateau growth phase, there is a distinct decrease in the cellular volume that is associated with a corresponding decrease in the proliferative and respiratory activity of the cells. The decline in cell volume is mainly due to a decrease in the content of cytoplasm, whereas the size of the nucleus is only slightly reduced. A concomitant decrease in the number of mitochondria per cell obviously accounts for the reduction in…
Effect of acetylcholine and dopamine iontophoretically applied on the sensory responsive caudate unit
1986
A putative integrative function of the striatum was evaluated through the study of the electrical activity of sensory responsive caudate neurones. Both nervous (radial nerve) and auditory stimulations were delivered in order to characterize populations of neurones affected by peripheral stimuli; the units were previously activated by iontophoretic glutamate. On these units the iontophoretic ejection of ACh and DA was tested. Experimental results demonstrated a prevalent excitatory effect of ACh, while DA appeared to exert a drastic decrease on firing rate. A comparison between peripheral stimuli and chemical substances was made. The result of such study showed a most important action of the…
The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts.
2009
BACKGROUND:Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells. The presence of a nuclear pool of glutathione has been demonstrated but its role in cellular proliferation and differentiation is still a matter of debate. PRINCIPAL FINDINGS:We have studied proliferation of 3T3 fibroblasts for a period of 5 days. Cells were treated with two well known depleting agents, diethyl maleate (DEM) and buthionine sulfoximine (BSO), and the cellular and nuclear glutathione levels were assessed by analytical and confocal microscopic techniques, respectively. Both agents decreased total cellular glutathione although depletion by BSO was more sustaine…
Subcellular distribution of choline acetyltransferase by immunogold electron microscopy in non-neuronal cells: Placenta, airways and murine embryonic…
2012
Abstract Aims Acetylcholine is synthesized in more or less all mammalian cells. However, little is known about the subcellular location of acetylcholine synthesis. Therefore, in the present experiments the subcellular location of the synthesizing enzyme choline acetyltransferase (ChAT) was investigated by anti-ChAT immunogold electron microscopy in human placenta and airways as well as in a murine embryonic stem cell line (CGR8 cell line). Main methods Human tissue was obtained as so-called surplus tissue (after delivery/surgical removal because of lung tumor); the CGR8 stem cell line was cultured under standard conditions. For human tissue a monoclonal mouse anti-ChAT antibody (ab) was use…
The role of hedonics in the Human Affectome.
2019
International audience; Experiencing pleasure and displeasure is a fundamental part of life. Hedonics guide behavior, affect decision-making, induce learning, and much more. As the positive and negative valence of feelings, hedonics are core processes that accompany emotion, motivation, and bodily states. Here, the affective neuroscience of pleasure and displeasure that has largely focused on the investigation of reward and pain processing, is reviewed. We describe the neurobiological systems of hedonics and factors that modulate hedonic experiences (e.g., cognition, learning, sensory input). Further, we review maladaptive and adaptive pleasure and displeasure functions in mental disorders …
Alteration of poly (ADP-Rib) synthesis during progesterone- caused gene expression in oviducts of quails.
1976
Summary The biological model of the selective induction of RNA synthesis in oviducts of estrogen stimulated immature quails by progesterone has been used to clarify whether poly (ADP-Rib) is involved in DNA transcription. The chromatin-bound as well as the soluble poly (ADP-Rib) polymerase has been isolated from oviducts and the optimal reaction conditions have been determined. The activities, as measured by the incorporation rates of NAD + into poly (ADP-Rib), of both, chromatin-bound « endogenouspolymerase (in the absence of « exogenousDNA and histones) and soluble enzyme (native DNA - lysine-rich histone ratio: 4.3) from progesterone treated quail oviducts, have been determined to be onl…
Fluorescent Core/Shell Nanoparticles for Specific Cell‐Nucleus Staining
2008
The highly fluorescent perylene-3,4,9,10-tetracarboxdiimide (PDI) chromophore is a popular dye and pigment because of its excellent chemical, thermal, and photochemical stability. Due to these outstanding properties, there have been several successful applications of PDI chromophores in various fields. Water-soluble and fluorescent PDI dyes have been used in biological applications such as the in vitro staining of cells and proteins. The combination of water solubility and high fluorescence quantum yield still represents a challenging goal since PDI dyes have a strong tendency to form aggregates in aqueous solution even at very low concentrations. Water solubility and high fluorescence quan…