Search results for "nucleus"
showing 10 items of 1803 documents
Human inducible nitric oxide synthase (iNOS) expression depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation fact…
2012
Human inducible nitric oxide synthase (iNOS) is regulated on the expressional level mostly by post-transcriptional mechanisms modulating the mRNA stability. Another important step in the control of eukaryotic gene expression is the nucleocytoplasmic mRNA transport. Most cellular mRNAs are exported via the TAP/Nxt complex of proteins. However, some mRNAs are transported by a different mechanism involving the nuclear export receptor CRM1. Treatment of DLD-1 cells with the CRM1 inhibitor leptomycin B (LMB) or anti-CRM1 siRNAs reduced cytokine-induced iNOS expression. We could demonstrate that the iNOS mRNA is exported from the nucleus in a CRM1-dependent manner. Since CRM1 itself does not poss…
Association of AUUUA-binding Protein with A + U-rich mRNA during nucleo-cytoplasmic transport
1992
Resealed nuclear envelope (NE) vesicles from rat liver containing entrapped exogenous RNA were used to study the effect of adenosine+uridine binding factor (AUBF), present in cytosolic cell extracts, on ATP-dependent transport of A+U-rich RNA (AU+RNA) and A+U-free RNA (AU-RNA) across the NE. This factor specifically binds to A+U-rich sequences present in the 3' untranslated regions of lymphokine and cytokine mRNAs, containing overlapping AUUUA boxes (granulocyte-macrophage colony stimulating factor, interleukin-3). Addition of AUBF to the extravesicular compartment markedly increased the efflux of the in vitro transcribed, capped and polyadenylated AU+ RNAs. Export of entrapped AU- control …
3'-Untranslated regions of oxidative phosphorylation mRNAs function in vivo, as enhancers of translation
2000
Recent findings have indicated that the 3´-untranslated region (3´-UTR) of the mRNA encoding the β-catalytic subunit of the mitochondrial H+-ATP synthase has an in vitro translation-enhancing activity (TEA) [Izquierdo and Cuezva, Mol. Cell. Biol. (1997) 17, 5255–5268; Izquierdo and Cuezva, Biochem. J. (2000) 346, 849–855]. In the present work, we have expressed chimaeric plasmids that encode mRNA variants of green fluorescent protein in normal rat kidney and liver clone 9 cells to determine whether the 3´-UTRs of nuclear-encoded mRNAs involved in the biogenesis of mitochondria have an intrinsic TEA. TEA is found in the 3´-UTR of the mRNAs encoding the α- and β-subunits of the rat H+-ATP syn…
"Figure 3.0" of "Measurements of Higher-Order Flow Harmonics in Au+Au Collisions at sqrt(s_NN) = 200 GeV"
2020
Charged hadron azimuthal anisotropy $v_2$ and $v_3$ vs centrality in Au+Au collisions at 200 GeV. The corresponding Npart value to each centrality is shown in Fig.3.2.
"Figure 2.5" of "Measurements of Higher-Order Flow Harmonics in Au+Au Collisions at sqrt(s_NN) = 200 GeV"
2020
Charged hadron azimuthal anisotropy $v_2$, and $v_3$ vs $p_T$ in 50-60% central Au+Au collisions at 200 GeV. The mean $$ in each $p_T$ bins used for the $v_n$ measurement is shown in Fig.2.6.
"Figure 2.0" of "Measurements of Higher-Order Flow Harmonics in Au+Au Collisions at sqrt(s_NN) = 200 GeV"
2020
Charged hadron azimuthal anisotropy $v_2$, $v_3$, and $v_4$ vs $p_T$ in 0-10% central Au+Au collisions at 200 GeV. The mean $$ in each $p_T$ bins used for the $v_n$ measurement is shown in Fig.2.6.
"Figure 2.1" of "Measurements of Higher-Order Flow Harmonics in Au+Au Collisions at sqrt(s_NN) = 200 GeV"
2020
Charged hadron azimuthal anisotropy $v_2$, $v_3$, and $v_4$ vs $p_T$ in 10-20% central Au+Au collisions at 200 GeV. The mean $$ in each $p_T$ bins used for the $v_n$ measurement is shown in Fig.2.6.
"Figure 2.6" of "Measurements of Higher-Order Flow Harmonics in Au+Au Collisions at sqrt(s_NN) = 200 GeV"
2020
Charged hadron mean $$ in each $p_T$ bins used for the $v_n$ measurements in Au+Au collisions at 200 GeV.
"Figure 2.2.1" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…
2021
Azimuthal anisotropy $v_n$ via the event-plane method for charge-combined $p\bar{p}$ in 30%���50% central Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.
"Appendix 2.0" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…
2021
Azimuthal anisotropy $v_n$ via the event-plane method for charge-combined $p\bar{p}$ in 10%���20% central Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.