Search results for "objective"

La pedagogía y la epistemología sometidas a examen. El inesperado potencial de la pedagogía «liberal» de John Elliott para la enseñanza de contenidos…

2014

In an attempt to provide an in-depth analysis of John Elliott’s prolonged contribution to the field of educational and curricular studies, the following paper starts by locating this pedagogue’s work in the context of key ideological debates of the 20th century, whose consequences shaped the realm of the social and the human sciences. Elliott’s stand at this ideological crossroads is defined as liberal, on account of the way he tied his own educational philosophy to the ethical sphere and to the means of education, in opposition to the learning of objective knowledge. The second part of the paper explores Elliott’s pedagogy from the point of view of the potential it may have to suggest a cu…

Adaptación y validación en población española del PROM: una medida objetiva del razonamiento moral prosocial [Adaptation and validation of prom in a …

2002

The assessment of pro-social moral reasoning through objective measurement is considered an important attainment in pro-social development research in recent decades. Based on N. Eisenberg's theory, PROM (Carlo et al., 1992) can objectively measure reasoning cognitive processes related to pro-social behaviour. This paper presents the adaptation and accreditation of this instrument for a Spanish adolescent population. The randomisation of the selected sample, its wide scope, and the reliability and validity of the results obtained make PROM a suitable instrument for evaluating the different pro-social reasoning types related to aid conduct amongst adolescents.

LGG-59. REMARKABLE OBJECTIVE RESPONSE AND FAVORABLE SURVIVAL FOR BRAF-V600E CHILDHOOD LOW-GRADE GLIOMAS TO BRAF INHIBITORS COMPARED CONVENTIONAL CHEM…

2018

Activation of the MAPK pathway represents a hallmark of pediatric low-grade glioma (pLGG) and is frequently caused by BRAF alterations. BRAF-V600E represent an aggressive type of pLGG with less than optimal response to conventional chemo-radiation approaches. While clinical trials using BRAF-V600E inhibitors are ongoing, these data are not yet available. We have assembled an international cohort of BRAF-V600E glioma patients treated off-label with BRAF inhibitors as a monotherapy. Complete molecular, clinical and imaging data is being collected and compared to previous chemo-radiation therapies. Ongoing data form the taskforce on 40 BRAF-V600E gliomas from 25 international institutions is s…

Mitotane Concentrations Influence Outcome in Patients With Advanced Adrenocortical Carcinoma

2020

Mitotane is the main option of treatment for advanced adrenocortical carcinoma (ACC). However, limited evidence is available regarding the impact of plasma mitotane levels on patient outcome. To address this question, we retrospectively analyzed patients with advanced ACC treated with mitotane for &ge

A Computationally Inexpensive Approach in Multiobjective Heat Exchanger Network Synthesis

2010

We consider a heat exchanger network synthesis problem formulated as a multiobjective optimization problem. The Pareto front of this problem is approximated with a new approximation approach and the preferred point on the approximation is found with the interactive multiobjective optimization method NIMBUS. Using the approximation makes the solution process computationally inexpensive. Finally, the preferred outcome on the Pareto front approximation is projected on the actual Pareto front. peerReviewed

A fuzzy programming method for optimization of autonomous logistics objects

2013

Recently several studies have explored the realization of autonomous control in production and logistic operations. In doing so, it has been tried to transmit the merit of decision-making from central controllers with offline decisions to decentralized controllers with local and real-time decision makings. However, this mission has still some drawbacks in practice. Lack of global optimization is one of them, i.e., the lost chain between the autonomous decentralized decisions at operational level and the centralized mathematical optimization with offline manner at tactical and strategic levels. This distinction can be reasonably solved by considering fuzzy parameters in mathematical programm…

Vection lies in the brain of the beholder: EEG parameters as an objective measurement of vection

2015

Assessing the in vitro optical quality of presbyopic solutions based on the axial modulation transfer function.

2016

Purpose To present a metric for assessing the in vitro optical quality of rotationally symmetrical optical elements based on volume calculation under the surface defined by the axial modulation transfer function (MTF). Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods The metric volume under the axial MTF was used to assess the optical quality of 2 rotationally symmetrical multifocal intraocular lenses (IOLs) within various defocus intervals (0.50 diopter [D], 0.75 D, and 1.00 D) and at various spatial frequency intervals (7.5 cycles per degree [cpd], 15.0 cpd, and 30.0 cpd). Results The far focus of the bifocal IOL yielded higher volume values at all spati…

A Generalized Framework for Optimal Sizing of Distributed Energy Resources in Micro-Grids Using an Indicator-Based Swarm Approach

2014

In this paper, a generalized double-shell framework for the optimal design of systems managed optimally according to different criteria is developed. Optimal design is traditionally carried out by means of minimum capital and management cost formulations and does not typically consider optimized operation. In this paper, the optimized multiobjective management is explicitly considered into the design formulation. The quality of each design solution is indeed defined by the evaluation of operational costs and capital costs. Besides, the assessment of the operational costs term is deduced by means of the solution of a multiobjective optimization problem. Each design solution is evaluated usin…

Crowded comparison operators for constraints handling in NSGA-II for optimal design of the compensation system in electrical distribution networks

2006

This paper proposes an improvement of an efficient multiobjective optimization algorithm, Non-dominated Sorting Genetic Algorithm II, NSGA-II, that has been here applied to solve the problem of optimal capacitors placement in distribution systems. The studied improvement involves the Crowded Comparison Operator and modifies it in order to handle several constraints. The problem of optimal location and sizing of capacitor banks for losses reduction and voltage profile flattening in medium voltage (MV) automated distribution systems is a difficult combinatorial constrained optimization problem which is deeply studied in literature. In this paper, the efficiency of the proposed Crowded Compari…