Mitotane Concentrations Influence Outcome in Patients With Advanced Adrenocortical Carcinoma

6533b852fe1ef96bd12aa361

RESEARCH PRODUCT

Mitotane Concentrations Influence Outcome in Patients With Advanced Adrenocortical Carcinoma

Carla Scaroni Silvia Della Casa Soraya Puglisi Massimo Torlontano Marco Russo Paola Berchialla Alessandra Quirino Paola Perotti Barbara Altieri Anna Calabrese Antonio Stigliano Maria Cristina De Martino Francesco Ferraù Filippo Ceccato Giuseppe Badalamenti Rosario Pivonello Giorgio Arnaldi Paola Loli Letizia Canu Vittoria Basile Laura Saba Massimo Terzolo

subject

Oncology mitotane Cancer Research medicine.medical_specialty Multivariate analysis recurrence Combination therapy Prognosi medicine.medical_treatment 030209 endocrinology & metabolism Disease lcsh:RC254-282 behavioral disciplines and activities survival Article 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Adrenocortical carcinoma Mitotane In patient adrenal cancer Objective response adrenal cancer; mitotane; prognosis; recurrence; survival Chemotherapy business.industry lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Oncology 030220 oncology & carcinogenesis prognosis business Adrenal cancer Mitotane Prognosis Recurrence Survival medicine.drug

description

Mitotane is the main option of treatment for advanced adrenocortical carcinoma (ACC). However, limited evidence is available regarding the impact of plasma mitotane levels on patient outcome. To address this question, we retrospectively analyzed patients with advanced ACC treated with mitotane for &ge

year	journal	country	edition	language
2020-03-20

10.3390/cancers12030740 http://hdl.handle.net/11573/1393259

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