Search results for "observation"

Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Resear…

2021

Abstract Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results A total of 9363 were available for this analysis. We identified three …

Creatividad en el diseño de instrumentos de recogida de datos: Las preferencias espaciales experimentadas por escolares

2016

La experimentación del entorno escolar por parte de los escolares, y la reflexión sobre las sensaciones provocadas por los estímulos que alberga; son de interés para determinar la calidad estética de los centros educativos. Son necesarios nuevos instrumentos de recogida de datos que permitan aproximarse a las voces de los escolares de temprana edad. A partir de la Investigación basada en las Artes y mediante técnicas de fomento de la creatividad proponemos un instrumento que combina: la observación participante, como forma de acercamiento; la entrevista y el lenguaje visual para la expresión de respuestas; y el análisis documental por categorías, para la obtención de información…

Grasp-specific motor resonance is influenced by the visibility of the observed actor

2016

AbstractMotor resonance is the modulation of M1 corticospinal excitability induced by observation of others' actions. Recent brain imaging studies have revealed that viewing videos of grasping actions led to a differential activation of the ventral premotor cortex depending on whether the entire person is viewed versus only their disembodied hand. Here we used transcranial magnetic stimulation (TMS) to examine motor evoked potentials (MEPs) in the first dorsal interosseous (FDI) and abductor digiti minimi (ADM) during observation of videos or static images in which a whole person or merely the hand was seen reaching and grasping a peanut (precision grip) or an apple (whole hand grasp). Part…

A European Observational Study to Evaluate the Safety and the Effectiveness of Safinamide in Routine Clinical Practice: The SYNAPSES Trial

2021

Background: Safinamide modulates both dopaminergic and glutamatergic systems with positive effects on motor and non-motor symptoms of Parkinson's disease (PD). The drug utilization study SYNAPSES was designed to investigate the use of safinamide in routine clinical practice, as recommended by the European Medicines Agency. Objective: To describe the occurrence of adverse events in PD patients treated with safinamide in real-life conditions. Methods: The SYNAPSES trial is an observational, European, multicenter, retrospective-prospective cohort study. Patients were followed up to 12 months with analyses performed in the overall population and in patients aged >75 years, with relevant comorbi…

The categorization of amateur cyclists as research participants: findings from an observational study.

2018

Sampling bias is an issue for research involving cyclists. The heterogeneity of cyclist populations, on the basis of skill level and riding purpose, can generate incorrect inferences about one specific segment of the population of interest. In addition, a more accurate categorization would be helpful when physiological parameters are not available. This study proposes using self-reported data to categorize amateur cyclist types by varying skill levels and riding purposes, therefore improving sample selection in experimental studies. A total of 986 cyclists completed an online questionnaire between February and October 2016. Two-step cluster analyses were performed to generate distinct group…

Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies

2017

[Background] The objective of this study will be to synthesize the epidemiological evidence and evaluate the validity of the associations between central nervous system disorders and the risk of developing or dying from cancer.

Risk of mortality among children, adolescents, and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-d…

2017

BACKGROUND: Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are childhood onset neurodevelopmental disorders that may persist into adulthood. ASD and ADHD tend to run in families and may have a significant negative impact on the health and longevity of those with the disorder and their relatives. The aim of this study will be to analyze the risk of mortality among children, adolescents, and adults with ASD or ADHD and their first-degree relatives. METHODS/DESIGN: We will conduct a systematic review and meta-analysis of observational studies. Searches of PubMed/MEDLINE, EMBASE, PsycINFO, SCOPUS, and ISI Web of Science will be used to identify epidemiologica…

Revista electrónica interuniversitaria de formación del profesorado

2016

Actualmente la inclusión es una de las mayores prioridades tanto del ámbito educativo como de la sociedad en general. El trabajo que exponemos se enmarca en el seno del debate abierto en torno a las distintas opiniones y creencias existentes sobre el tema. Concretamente, mostramos los resultados obtenidos en un estudio de caso, al evaluar las percepciones del profesorado y familias del alumnado de un aula de Comunicación y Lenguaje valenciana, sobre el proceso de inclusión realizado a lo largo de sus cinco años de funcionamiento. A través de un diseño de investigación mixto utilizamos instrumentos de recogida de datos cualitativos tales como la entrevista y la observación participante así c…

Current trends in orthodontic journals listed in Journal Citation Reports. A bibliometric study.

2018

Introduction The aim of this study is to analyze articles published in orthodontic journals included in Journal Citation Reports (JCR) to determine current trends in orthodontic publishing. Methods Articles included in orthodontic journals in 2016 JCR and published during 2007-2017 were selected. After applying inclusion criteria, author-based parameters (article title, first author's name, institution and sex, number of authors, number of affiliations, first author's origin, and geographic origin), article-based parameters (article type, main topic, and research design), and the number of cites and self-cites were registered for each article. Results A total of 7119 articles were analyzed,…

2021

An observational cross-sectional survey was planned to analyze the weekly workload reduction of German dentists during lockdown due to the global COVID-19 pandemic. Participants were predominantly members of the Free Association of German Dentists and filled in an online questionnaire. The questionnaire was sent to a total of 9416 dentists, with a response rate of 27.98% (n = 2635). Respondents were divided into seven macro areas by gross domestic product. Nearly two-thirds of dentists (65.16%) reported a reduction in their practice workload of more than 50% compared to the pre-pandemic period with statistically significant differences between German macro areas (p < 0.01). Weekly worklo…