Search results for "odor"
showing 10 items of 569 documents
Identification of a lysyl residue defining the binding specificity of a human odorant-binding protein
2008
International audience
Novel canine odorant binding proteins
2022
The present invention relates to the use of a sequence chosen among Seq ID No 3, Seq ID No l, Seq ID No 2, Seq ID No 4, Seq ID No 5, Seq ID No 6, Seq ID No 7, Seq ID No 8, and functional variants thereof, as an odorant binding protein (OBP).
Activity mappings in olfactory bulb of newborn rabbits elicited by odor stimulation using quantitative manganese enhanced MRI
2007
International audience
Retention-release equilibrium of aroma compounds in polysaccharide gels: study by quantitative structure-activity/property relationships approach
2010
The nature and amount of constituents in food greatly influence aroma release. Pectins and carrageenans are common used thickeners, but their effect on the release of aroma compounds has been studied more frequently for non- homogeneous products than for thickeners separately. The purpose of this work was to study and compare their respective effects in simple model systems. In this way, the release of 13 aroma compounds was analysed by headspace analysis at equilibrium in pure water, i-carrageenan and pectin gels. To evaluate the influence of the chemical structure of aroma com- pounds on retention/release equilibrium between vapour phase and gels, we used a quantitative structure-activity…
Glutathione conjugation of the rabbit mammary pheromone 2-methylbut-2-enal
2008
International audience; In the process of smell, the olfactory signal is initiated by the binding of odorous molecules to olfactory receptors. In the receptor environment,associated events are supposed to modulate this signal.Thus, the xenobiotic metabolizing enzymes, potentially involved in the clearance of the odorous molecules, could modulate the availability of these molecules for the olfactory receptors, and consequently could participate indirectly in the olfactory signal termination. A mammary pheromone, which is an odorous aldehyde (2-methylbut-2-enal or 2MB2) has been recently characterized in the rabbit by our group. The aim of this work was to elucidate the metabolism of 2MB2 in …
Les récepteurs olfactifs et le codage des odeurs
2008
The first step of the olfactory detection involves the activation by odorants of olfactory receptors, which are membrane proteins embedded in the membrane of olfactory neurons. Odour coding results from the combinatory activation of a set of receptors and rests on their clonal expression. Neuronal olfactory connexion leads to the formation, in the cortex, of a specific sensory map, which gives rise to the odor perception. This combinatorial system allows, with approximately 340 different receptors, to discriminate myriads of odorants that are natural or not (new cooking flavours, synthetic chemicals…). The extreme olfactory genome diversity in human beings may explain different food behavio…
Activity and expression of drug metabolizing enzymes in olfactory mucosa of rats treated by hepatic inducers
2008
International audience; Several drug-metabolizing enzymes (DME), such as cytochrome P450- dependent monooxygenases (CYP) and transferases have been characterized in the olfactory epithelium. Some of them are preferentially expressed in this tissue, while others are similar to those present in the liver. The role of these enzymes remains unclear. Since the olfactory mucosa is in direct contact with the external environment, these enzymes can contribute to the detoxification of chemical compounds. In addition, these enzymes could be involved in the olfaction process, especially in the biotransformation of odorants. Indeed, the rapid inactivation and clearance of odorants is a prerequisite for…
Implication of an odorant-binding protein in precopulatory behaviour and interaction with the bacterial microbiota
2023
Chemoreception allows animals to detect nutritive food and avoid toxic compounds. Volatile and non-volatile chemical compounds, which are detected by olfactory and gustatory sensory organs, can trigger feeding and reproductive behaviours in animals such as Drosophila melanogaster. Inside chemosensory organs, perireceptor proteins like odorant-binding proteins (OBPs) serve to transport odorant and tastant molecule to dedicated receptors. OBPs are not only involved in chemoreception but also in several other functions. A recent study revealed an interaction between insect microbiota and OBP expression while another one showed that microbes can promote nutrient harvesting on food. In our proje…
Dei, semidei ed eroi nella Sicilia greca
2022
Quando la presenza di Odisseo comincia ad essere localizzata anche in Sicilia, a partire dalla seconda metà del V secolo a.C., nell’isola erano già presenti molti culti e presenze divine ed eroiche. In questa breve sintesi il paesaggio religioso siciliano è descritto attraverso quel prezioso Baedeker ante litteram che è (almeno per alcuni aspetti) la Biblioteca diodorea. When the presence of Odysseus also began to be localised in Sicily, starting in the second half of the 5th century BC, many cults and divine and heroic presences were already present on the island. In this brief summary, the Sicilian religious landscape is described through that precious Baedeker ante litteram that is (at l…
Mammary olfactory signalisation in females and odor processing in neonates: ways evolved by rabbits and humans
2009
International audience; Mammalian females have long been known to release olfactory attraction in their offspring. Mammary odor cues control infant state, attention and directional responses, delay distress responses, stimulate breathing and positive oral actions, and finally can boost learning. Here, we survey female-offspring odor communication in two mammalian species - European rabbits and humans - taken as representatives of evolutionary extremes in terms of structure and dynamics of mother-infant relations, and level of neonatal autonomy. Despite these early psychobiological differences, females in both species have evolved mammary structures combining multiple sources of endogenous a…