Search results for "oftware"
showing 10 items of 7396 documents
PyDSC: a simple tool to treat differential scanning calorimetry data
2020
AbstractHerein, we describe an open-source, Python-based, script to treat the output of differential scanning calorimetry (DSC) experiments, called pyDSC, available free of charge for download at https://github.com/leonardo-chiappisi/pyDSC under a GNU General Public License v3.0. The main aim of this program is to provide the community with a simple program to analyze raw DSC data. Key features include the correction from spurious signals, and, most importantly, the baseline is computed with a robust, physically consistent approach. We also show that the baseline correction routine implemented in the script is significantly more reproducible than different standard ones proposed by propriet…
Reestimating a minimum acceptable geocoding hit rate for conducting a spatial analysis
2019
Geocoding consists in converting a textual description of a location into coordinates. Hence, geocoding a dataset of events has to be carried out before performing a spatial analysis of some data. ...
Combining Supervised and Unsupervised Learning to Discover Emotional Classes
2017
Most previous work in emotion recognition has fixed the available classes in advance, and attempted to classify samples into one of these classes using a supervised learning approach. In this paper, we present preliminary work on combining supervised and unsupervised learning to discover potential latent classes which were not initially considered. To illustrate the potential of this hybrid approach, we have used a Self-Organizing Map (SOM) to organize a large number of Electroencephalogram (EEG) signals from subjects watching videos, according to their internal structure. Results suggest that a more useful labelling scheme could be produced by analysing the resulting topology in relation t…
Large-scale random features for kernel regression
2015
Kernel methods constitute a family of powerful machine learning algorithms, which have found wide use in remote sensing and geosciences. However, kernel methods are still not widely adopted because of the high computational cost when dealing with large scale problems, such as the inversion of radiative transfer models. This paper introduces the method of random kitchen sinks (RKS) for fast statistical retrieval of bio-geo-physical parameters. The RKS method allows to approximate a kernel matrix with a set of random bases sampled from the Fourier domain. We extend their use to other bases, such as wavelets, stumps, and Walsh expansions. We show that kernel regression is now possible for data…
Developing design knowledge and a conceptual model for virtual reality learning environments
2021
This chapter focuses on applying design science research for virtual reality learning environment (VRLE) design processes. Six selected case studies are presented in the context of VRLEs. The case selections were analyzed in terms of their contributions to design knowledge. The objective of this book chapter is twofold: 1) for researchers, the design knowledge contributions of case studies are highlighted for future reference, and 2) for developers and practitioners, design principles are presented for the development of VRLEs. The final outcome of the present study is a conceptual model describing the current design knowledge in the field of VRLEs and identifying the research gaps that sho…
Learning Improved Feature Rankings through Decremental Input Pruning for Support Vector Based Drug Activity Prediction
2010
The use of certain machine learning and pattern recognition tools for automated pharmacological drug design has been recently introduced. Different families of learning algorithms and Support Vector Machines in particular have been applied to the task of associating observed chemical properties and pharmacological activities to certain kinds of representations of the candidate compounds. The purpose of this work, is to select an appropriate feature ordering from a large set of molecular descriptors usually used in the domain of Drug Activity Characterization. To this end, a new input pruning method is introduced and assessed with respect to commonly used feature ranking algorithms.
Revisitation of Nonorthogonal Spin Adaptation in Coupled Cluster Theory.
2015
The benefits of what is alternatively called a nonorthogonally spin-adapted, spin-free, or orbital representation of the coupled cluster equations is discussed relative to orthogonally spin-adapted, spin-orbital, and spin-integrated theories. In particular, specific linear combinations of the orbital cluster amplitudes, denoted spin-summed amplitudes, are shown to reduce the number of contractions that must be explicitly performed and to simplify the expressions and their derivation. The computational efficiency of the spin-summed approach is discussed and compared to orthogonally spin-adapted and spin-integrated approaches. The spin-summed approach is shown to have significant computationa…
Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples.
2013
Flow cytometry is the prototypical assay for multi-parameter single cell analysis, and is essential in vaccine and biomarker research for the enumeration of antigen-specific lymphocytes that are often found in extremely low frequencies (0.1% or less). Standard analysis of flow cytometry data relies on visual identification of cell subsets by experts, a process that is subjective and often difficult to reproduce. An alternative and more objective approach is the use of statistical models to identify cell subsets of interest in an automated fashion. Two specific challenges for automated analysis are to detect extremely low frequency event subsets without biasing the estimate by pre-processing…
Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assessment.
2007
Abstract Background Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. However, the alignment methods seem inadequate for post-genomic studies since they do not scale well with data set size and they seem to be confined only to genomic and proteomic sequences. Therefore, alignment-free similarity measures are actively pursued. Among those, USM (Universal Similarity Metric) has gained prominence. It is based on the deep theory of Kolmogorov Complexity and universality is its most novel striking feature. Since it can only be approximated via data compression, USM is a methodology rath…
Machine Learning Techniques for Intrusion Detection: A Comparative Analysis
2016
International audience; With the growth of internet world has transformed into a global market with all monetary and business exercises being carried online. Being the most imperative resource of the developing scene, it is the vulnerable object and hence needs to be secured from the users with dangerous personality set. Since the Internet does not have focal surveillance component, assailants once in a while, utilizing varied and advancing hacking topologies discover a path to bypass framework " s security and one such collection of assaults is Intrusion. An intrusion is a movement of breaking into the framework by compromising the security arrangements of the framework set up. The techniq…