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showing 10 items of 4837 documents

A Nonlinear Approach to Brain Function: Deterministic Chaos and Sleep EEG

1992

In order to perform a nonlinear dimensional analysis of the sleep electroencephalogram (EEG), we applied an algorithm proposed by Grassberger and Procaccia to calculate the correlation dimension D2 of different sleep stages under Lorazepam medication versus placebo. This correlation dimension characterizes the dynamics of the sleep EEG and it estimates the degrees of freedom of the signal under study. We demonstrate that slow-wave sleep depicts a much smaller dimensionality than light or rapid eye movement (REM) sleep, and that Lorazepam does not alter the EEG's dimensionality except in stage II and REM.

AdultMaleCorrelation dimensionRapid eye movement sleepSleep REMElectroencephalographyLorazepamHippocampusModels BiologicalPhysiology (medical)mental disordersmedicineAnimalsHumansSlow-wave sleepAuditory CortexSleep Stagesmedicine.diagnostic_testbusiness.industryBrainEye movementElectroencephalographyPattern recognitionPlacebo EffectSleep in non-human animalsElectrodes ImplantedCatsSleep StagesNeurology (clinical)Artificial intelligenceSleepbusinessPsychologyNeuroscienceCurse of dimensionalitySleep
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Expanded gentamicin volume of distribution in critically ill adult patients receiving total parenteral nutrition

1995

Aminoglycoside antibiotics distribute into the extracellular fluid compartment and are eliminated by the kidney via glomerular filtration. Malnutrition and total parenteral nutrition influence the fluid and electrolyte status of the patient, and cause organ changes. The purpose of this clinical study was to characterize the kinetic behaviour of gentamicin in the parenterally fed critically ill adult patient. Eighty-six critically ill adult patients treated with gentamicin for severe Gram-negative infections were enrolled in the study (mean +/- SD): age, 60 +/- 14 years; weight, 69.4 +/- 10.2 kg; height, 163 +/- 10 cm; 22 females and 64 males. Four study groups were defined (2 x 2): total pa…

AdultMaleCritical IllnessRenal functionFluorescence PolarizationCommunicable DiseasesPharmacokineticsExtracellular fluidmedicineHumansPharmacology (medical)Infusions IntravenousAgedAntibacterial agentPharmacologyVolume of distributionbusiness.industryAminoglycosideMiddle AgedAnti-Bacterial AgentsNutrition DisordersParenteral nutritionAnesthesiaRegression AnalysisFemaleParenteral Nutrition TotalGentamicinGentamicinsbusinessmedicine.drugJournal of Clinical Pharmacy and Therapeutics
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Masculine Gender Role Stress

2003

Eisler and Blalock (Clin. Psychol. Rev. 11 (1991) 45) developed a cognitively mediated notion of Masculine Gender Role Stress (MGRS) which assumes that rigid commitment to masculine schemata for appraisal and coping with life's problems may both produce stress and result in dysfunctional coping patterns in men. Previous findings obtained in a non-clinical sample pointed to the ability of the MGRS General scale to predict different forms of irrational fears. Using a predominantly psychologically distressed sample, the present study replicated this finding. In addition, different subordinate concepts of MGRS (Physical inadequacy, Emotional inexpressiveness, Subordination to women, Intellectua…

AdultMaleDISORDERCoping (psychology)Obsessive-Compulsive DisorderPsychometricsAdolescentPersonality InventoryPsychometricsmedia_common.quotation_subjectSelf-conceptExperimental and Cognitive PsychologyDysfunctional familyDISSIMULATIONDevelopmental psychologyPhobic disorderFEARSArts and Humanities (miscellaneous)phobic avoidanceCHECKERSmedicinePersonalityHumansIdentification PsychologicalMarriageAPPRAISALSCALEmedia_commonAgedMasculine Gender Role Stress (MGRS) scalePERSONALITYGender Identityobsessive-compulsive behaviourFearpredictionMiddle Agedmedicine.diseasegender role stressSelf ConceptPsychiatry and Mental healthClinical PsychologyPhobic DisordersFemaleSEXPersonality Assessment InventoryPsychologySocial psychologyAnxiety disorderStress PsychologicalJournal of Behavior Therapy and Experimental Psychiatry
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Taking both sides: do unilateral anterior temporal lobe lesions disrupt semantic memory?

2010

The most selective disorder of central conceptual knowledge arises in semantic dementia, a degenerative condition associated with bilateral atrophy of the inferior and polar regions of the temporal lobes. Likewise, semantic impairment in both herpes simplex virus encephalitis and Alzheimer's disease is typically associated with bilateral, anterior temporal pathology. These findings suggest that conceptual representations are supported via an interconnected, bilateral, anterior temporal network and that it may take damage to both sides to produce an unequivocal deficit of central semantic memory. We tested and supported this hypothesis by investigating a case series of 20 patients with unila…

AdultMaleDatabases Factualunilateral anterior temporal lobe lesions semantic memorymedicine.medical_treatmentSemantic dementiaNeuropsychological TestsTemporal lobeYoung AdultEpilepsyMemorymedicineHumansSemantic memoryCognitive neuropsychologyAgedMemory DisordersSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaCognitionMiddle Agedmedicine.diseaseTemporal LobeFunctional imagingTranscranial magnetic stimulationFemaleNeurology (clinical)AtrophyPsychologyNeuroscience
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Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study

2018

Introduction The potential impact of targeting different components of an adverse lipid profile in populations with multiple cardiovascular risk factors is not completely clear. This study aims to assess the association between different components of the standard lipid profile with all-cause mortality and hospitalization due to cardiovascular events in a high-risk population. Methods This prospective registry included high risk adults over 30 years old free of cardiovascular disease (2008–2012). Diagnosis of hypertension, dyslipidemia or diabetes mellitus was inclusion criterion. Lipid biomarkers were evaluated. Primary endpoints were all-cause mortality and hospital admission due to coron…

AdultMaleDeath RatesEndocrine Disorderslcsh:MedicineBlood PressureCoronary DiseaseCardiovascular Medicine030204 cardiovascular system & hematologyBiochemistryVascular Medicine03 medical and health sciencesEndocrinology0302 clinical medicinePopulation MetricsRisk FactorsMalalties ComplicacionsMortalitatMedicine and Health SciencesDiabetes MellitusHumans030212 general & internal medicinelcsh:ScienceTriglyceridesSistema cardiovascularAgedMultidisciplinaryPopulation BiologyCholesterol HDLlcsh:RBiology and Life SciencesCorrectionCholesterol LDLMiddle AgedLipidsHospitalizationStrokeCholesterolNephrologyCardiovascular DiseasesMetabolic DisordersHypertensionlipids (amino acids peptides and proteins)Femalelcsh:QBiomarkersResearch ArticlePLOS ONE
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Reliability of DSM-III Anxiety Disorders - Check-List Versus Structured Interview

1988

AdultMaleDepressive DisorderGeneral MedicineMiddle AgedAnxiety DisordersPsychiatry and Mental healthStructured interviewmedicineHumansAnxietyFemalePharmacology (medical)medicine.symptomPsychologyCheck ListReliability (statistics)AgedClinical psychologyPharmacopsychiatry
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The 2D:4D Ratio as a Predictor of the Risk of Recidivism after Court-mandated Intervention Program for Intimate Partner Violence Perpetrators.

2016

Differences in aggressive behavior could be partially explained by differential prenatal exposure to testosterone (T). A peripheral marker of prenatal T exposure is the 2D:4D ratio, which has shown a negative correlation with self-reported aggression in violent men. This study tested the direct association of the 2D:4D ratio with anger expression and the risk of recidivism in intimate partner violence (IPV) perpetrators after psychotherapeutic intervention program. The sample consisted of IPV perpetrators, whose 2D:4D ratio was measured before the intervention. Moreover, after the intervention, anger expression and risk of recidivism in IPV were assessed. Smaller 2D:4D ratio, especially of …

AdultMaleDigit ratioCoping (psychology)medicine.medical_specialtyPersonality Inventorymedia_common.quotation_subjectIntimate Partner Violence050109 social psychologyAngerAngerbehavioral disciplines and activitiesRisk AssessmentPathology and Forensic MedicineFingersmental disordersGeneticsmedicineHumans0501 psychology and cognitive sciencesPsychiatrymedia_commonRecidivismAggressionAntisocial personality disorder05 social sciencesAntisocial Personality Disordermedicine.diseaseAggressionRecidivismSpainDomestic violenceFemalemedicine.symptomPsychologyRisk assessment050104 developmental & child psychologyClinical psychologyJournal of forensic sciences
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Immunoglobulin A response to acute stress in intimate partner violence perpetrators: the role of anger expression-out and testosterone.

2014

Aggressive behavior and immune activity are shown to be positively associated in perpetrators of intimate partner violence (IPV). This relationship follows an inverted-U curve, with the most violent individuals showing lower levels of immunocompetence than those with a history of moderate violence. Moreover, the activational and organizational effects of testosterone (T) may indirectly stimulate the immune response. Given this, we used the Trier Social Stress Test to establish whether the salivary immunoglobulin A (sIgA) response to acute stress was a specific psychobiological feature in perpetrators of intimate partner violence (IPV). IPV perpetrators showed higher sIgA levels than control…

AdultMaleDigit ratiomedicine.medical_specialtyStatistics as TopicPoison controlbehavioral disciplines and activitiesSuicide preventionFingersYoung AdultPhlebotomymental disordersInjury preventionmedicineTrier social stress testHumansInterpersonal RelationsTestosteronePsychiatrySalivaAnalysis of VariancePsychological TestsGeneral NeuroscienceHuman factors and ergonomicsTestosterone (patch)social sciencesMiddle AgedImmunoglobulin AAggressionNeuropsychology and Physiological PsychologyArea Under CurveCase-Control StudiesDomestic violencePsychologyStress PsychologicalClinical psychologyBiological psychology
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Recovery from depressive symptoms, state anxiety and post-traumatic stress disorder in women exposed to physical and psychological, but not to psycho…

2010

Abstract Background It is well established that intimate male partner violence (IPV) has a high impact on women's mental health. It is necessary to further investigate this impact longitudinally to assess the factors that contribute to its recovery or deterioration. The objective of this study was to assess the course of depressive, anxiety and post-traumatic stress disorder (PTSD) symptoms and suicidal behavior over a three-year follow-up in female victims of IPV. Methods Women (n = 91) who participated in our previous cross-sectional study, and who had been either physically/psychologically (n = 33) or psychologically abused (n = 23) by their male partners, were evaluated three years late…

AdultMaleDomestic ViolenceLongitudinal studymedicine.medical_specialtylcsh:RC435-571Health StatuseducationPoison controlComorbiditySocial EnvironmentSuicide preventionbehavioral disciplines and activitiesLife Change EventsStress Disorders Post-TraumaticSocial supportSex FactorsSurveys and Questionnaireslcsh:PsychiatryOutcome Assessment Health Caremental disordersmedicineHumansLongitudinal StudiesPsychiatryDepressionTraumatic stressSocial Supportsocial sciencesMiddle AgedAnxiety DisordersMental healthPsychiatry and Mental healthMental HealthSpouse AbuseWomen's HealthAnxietyDomestic violencepopulation characteristicsFemalemedicine.symptomPsychologyFollow-Up StudiesResearch ArticleClinical psychology
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Dopamine-modulated aversive emotion processing fails in alcohol-dependent patients.

2013

Negative mood states after alco- hol detoxifi cation may enhance the relapse risk. As recently shown in healthy volunteers, dopamine storage capacity ( V d ) in the left amy- gdala was positively correlated with functional activation in the left amygdala and anterior cin- gulate cortex (ACC) during an emotional task; high functional connectivity between the amy- gdala and the ACC, a region important for emo- tion regulation, was associated with low trait anxiety. Based on these fi ndings, we now tested whether detoxifi ed alcohol-dependent patients have a disrupted modulation of the anterior cin- gulate cortex activation in response to aversive stimuli by amygdala dopamine. Furthermore, we …

AdultMaleDopamineEmotionsAnxietyAmygdalaNeuroimagingDopaminemedicineImage Processing Computer-AssistedHumansPharmacology (medical)Cerebral Cortexmedicine.diagnostic_testSmokingMagnetic resonance imagingGeneral MedicineAmygdalaMagnetic Resonance ImagingCortex (botany)Diagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthAffectAlcoholismmedicine.anatomical_structurePositron emission tomographyPositron-Emission TomographyAnxietyFemalemedicine.symptomAversive StimulusRadiopharmaceuticalsPsychologyNeurosciencepsychological phenomena and processesPhotic Stimulationmedicine.drugPharmacopsychiatry
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