Search results for "outcomes."

showing 10 items of 434 documents

Global variation in anastomosis and end colostomy formation following left-sided colorectal resection

2019

Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…

Malemodelos logísticosmedicine.medical_treatmenthumanossurgial careColorectal Neoplasmpaíses desarrolladosLogistic regressionoutcomesGlobal Healthurgencias médicas0302 clinical medicinepaíses en desarrolloSurgicalestudios prospectivosColostomy80 and overglobalsurg030212 general & internal medicineProspective StudiesProspective cohort studyMultivariate Analysimediana edadCancerAged 80 and overEmergencieancianoAnastomosis colorectal resection colostomyAnastomosis SurgicalColostomyGeneral MedicineMiddle Agedadultocolostomy; colorectal cancer; human developlment index3. Good healthColo-Rectal Cancertraditional healersElective Surgical Procedures030220 oncology & carcinogenesisFemaleColorectal Neoplasms6.4 Surgerylow incomeCohort studyHumanDeveloped CountrieAdultAdult; Aged; Aged 80 and over; Anastomosis Surgical; Colorectal Neoplasms; Colostomy; Elective Surgical Procedures; Emergencies; Female; Global Health; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Developed Countries; Developing Countriesmedicine.medical_specialtyneoplasias colorrectalesLogistic Modelcancer anastomosis surgical income stomas colostomy procedure colorectal resection end colostomy emergency surgical procedure human development indexdelayAnastomosishuman developlment indexPerforation (oil well)lcsh:Surgerycolorectal cancerAnastomosisGlobalSurg CollaborativeNO03 medical and health sciencesCase mix indexClinical ResearchmedicinecancerHumansanálisis multifactorialDeveloping CountriesAgedemergency abdominal surgery low income surgial care traditional healers cancer mortality outcomes delayElective Surgical Procedurebusiness.industryKirurgiDeveloped Countriesleft colon resection anastomosis end colostomyEvaluation of treatments and therapeutic interventionslcsh:RD1-811Odds ratiomortalitySurgeryProspective StudieLogistic ModelsMultivariate AnalysisSurgeryEmergenciesbusinessDigestive Diseasescolostomíaemergency abdominal surgery
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Continuous Femoral Catheter for Postoperative Analgesia After Total Knee Arthroplasty

2020

Introduction Postoperative pain management in the total knee replacement (TKR) represent a fundamental step for a positive outcome, allowing rapid mobilization, already on the first day. Further, continuous peripheral nerve block techniques have been reported to allow effective and safe control of acute postoperative pain, ensuring the implementation and completion of an accurate and intensive joint rehabilitation program. Aim The aim of this study was to assess early mobility and compliance of patients that underwent TKR surgery using the femoral block. Methods For the study, all patients that underwent TKR from 2015 to 2018 with ASA score between II-III was evaluated. Patients underwent v…

Malemusculoskeletal diseasesmedicine.medical_specialtyKnee JointJoint mobilizationmedicine.medical_treatmentTotal knee arthroplastyContinuous femoral block Knee Arthroplasty Anesthesia Loco-Regional Treatment Outcomes.Settore MED/41 - AnestesiologiaOutcomesCatheterization03 medical and health sciences0302 clinical medicinePatient satisfactionFemoral nerveQuality of life030202 anesthesiologyContinuous femoral blockmedicineSettore MED/33 - Malattie Apparato LocomotoreHumansAnesthesiaKnee ArthroplastyArthroplasty Replacement KneeEarly AmbulationAgedAged 80 and overPain Postoperative030222 orthopedicsRehabilitationbusiness.industryLoco-Regional TreatmentProfessional PaperAnalgesia Patient-ControlledNerve BlockGeneral MedicineMiddle AgedSurgeryMuscle relaxationMidazolamFemalebusinessmedicine.drug
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Body mass index and complications following major gastrointestinal surgery

2018

Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastroint…

MaleobesityMultivariate analysisGastrointestinal DiseasesIMPACTSettore MED/18 - CHIRURGIA GENERALEBody mass index; Body weight; Digestive tract; Gastrointestinal tract; Obesity; Postoperative complications; Gastroenterologydigestive tractTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicineGastrointestinal tractRisk FactorsMedicineProspective StudiesProspective cohort studyBody mass indexBody mass index; Body weight; Digestive tract; Gastrointestinal tract; Obesity; Postoperative complications; Aged; Europe; Female; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Obesity; Postoperative Complications; Prospective Studies; Risk Factors; Body Mass IndexGastrointestinal NeoplasmsOUTCOMESPostoperative complications; body mass index; body weight; digestive tract; gastrointestinal tract; obesityGastroenterologyMiddle AgedBody mass index; Body weight; Digestive tract; Gastrointestinal tract; Obesity; Postoperative complicationsEurope030220 oncology & carcinogenesisMeta-analysisUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]CohortFemale030211 gastroenterology & hepatologyCohort studymedicine.medical_specialtybody mass indexMalignancyNO03 medical and health sciencesPostoperative complicationsbody weightSDG 3 - Good Health and Well-beingHumansDigestive tractObesityAgedbusiness.industrypostoperative complications; obesity; digestive tract; gastrointestinal tract; body mass index; body weightMORTALITYBody weightmedicine.diseaseObesitySettore MED/18SurgeryPostoperative complicationPostoperative Complications Obesity Digestive Tract Gastrointestinal Tract Body Mass Index Body Weight.gastrointestinal tractbusinessBody mass indexColorectal Disease
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Role of abdominal obesity for functional outcomes and complications in men treated with radical prostatectomy for prostate cancer: results of the Mul…

2014

Objective. This study aimed to evaluate the impact of abdominal obesity on preoperative features, complications and functional outcomes of men treated with radical prostatectomy (RP) for prostate cancer. Material and methods. In 2006 a multicentre Italian report on RP evaluated the surgical and functional characteristics of prostate cancer and RP outcomes. Age and waist circumference (WC) were recorded. Abdominal obesity was defined as a WC of at least 102 cm. International Index of Erectile Function (IIEF) score, prostate-specific antigen, prostate volume, tumour characteristics, presence/absence of perioperative complications and the number of blood units transfused were recorded. Preoper…

Maleobesitymedicine.medical_treatmentLogistic regressionsurgeryProstate cancerPostoperative ComplicationsErectile DysfunctionProstateProspective StudiesProspective cohort studyAbdominal obesityProstatectomyMiddle Agedprostate cancerTreatment Outcomemedicine.anatomical_structureItalyNephrologyObesity AbdominalabdominalepidemiologyWaist Circumferencemedicine.symptomHumanmedicine.medical_specialtyWaistcomplicationsUrologyUrologymethodsabdominal obesityincontinenceepidemiology/etiologymedicineHumansAgedProstatectomybusiness.industryfunctional outcomes and complicationProstatic Neoplasmsmethods; abdominal; prospective studies; erectile dysfunction; male; obesity; epidemiology; middle aged; treatment outcome; humans; prostatic neoplasms; epidemiology/etiology; surgery; aged; incontinence; complications; waist circumference; prostatectomy; postoperative complications; prostate cancer; urinary incontinence; italyPerioperativemedicine.diseaseradical prostatectomyMIRRORProspective StudieUrinary IncontinenceProstatic NeoplasmPostoperative ComplicationbusinessComplicationScandinavian Journal of Urology
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Chromophobe renal cell carcinoma (RCC): oncological outcomes and prognostic factors in a large multicentre series.

2011

Study Type - Outcomes (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? About 80% of RCCs have clear cell histology, and consistent data are available about the clinical and histological characteristics of this histological subtype. Conversely, less attention has been dedicated to the study of non-clear cell renal tumours Specifically, published data show that chromophobe RCC (ChRCC) have often favourable pathological stages and better nuclear grades as well as a lower risk of metastasizing compared with clear cell RCC (ccRCC). Patients with ChRCC were shown to have significantly higher cancer-specific survival (CSS) probabilities compared with ccRCC. H…

Malerenal cell carcinomachromophobe RCC; prognostic factors; Carcinoma; Nephrectomy; Prognosis; Renal cellKaplan-Meier EstimateChromophobe renal cell carcinomaCarcinoma; Chromophobe; Nephrectomy; Prognosis; Renal cellchromophobe RCCNephrectomyHumansRenal cellCarcinoma Renal CellChromophobecarcinoma; renal cell; chromophobe; prognosis; nephrectomyCarcinomaKidney Neoplasmprognostic factorsMiddle AgedPrognosisKidney Neoplasmsoncological outcamesrenal cell carcinoma; prognostic factorsoncological outcomes and prognostic factorsChromophobe renal cell carcinoma; prognostic factors; oncological outcamesFemaleprognosiHuman
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Long-term outcomes in men and women with ST-segment elevation myocardial infarction and incomplete reperfusion after a primary percutaneous coronary …

2019

Background The failure of reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI) is more frequent than considered previously. Aim To evaluate sex-related differences in long-term outcomes in patients with STEMI and incomplete infarct-related artery reperfusion after a primary percutaneous coronary intervention. Patients and methods Of consecutive 42 752 patients with STEMI hospitalized between 2009 and 2011 in Poland, we analyzed a group of 766 (35%) women and 1453 (65%) men with less than thrombolysis in myocardial infarction (TIMI) flow grade 3 following a primary percutaneous coronary intervention. Results In the 2-year follow-up, the mortality rate among…

Malesex differencesTime Factorsmedicine.medical_treatmentCoronary Artery Disease030204 cardiovascular system & hematology0302 clinical medicineRisk FactorsPrevalenceRegistriesTreatment Failure030212 general & internal medicineMyocardial infarctionStrokeAged 80 and overIncidenceMortality rateHazard ratioGeneral MedicineMiddle Agedprimary percutaneous coronary interventionCardiologyFemaleCardiology and Cardiovascular Medicinelong-term outcomesTIMImedicine.medical_specialtyPatient ReadmissionRisk Assessment03 medical and health sciencesPercutaneous Coronary InterventionSex FactorsReperfusion therapyCoronary CirculationInternal medicinemedicineHumanscardiovascular diseasesAgedHeart Failurebusiness.industryPercutaneous coronary interventionHealth Status Disparitiesmedicine.diseaseST-segment elevation myocardial infarctionincomplete reperfusionHeart failureST Elevation Myocardial InfarctionPolandbusinessCoronary Artery Disease
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Reliability and validity of the Finnish version of the Visual Analogue Scale Foot and Ankle (VAS-FA).

2018

Background: There have previously been no validated foot and ankle-specific patient-reported outcome measures in Finnish. Methods: The Visual Analogue Scale Foot and Ankle (VAS-FA) was translated and adapted into Finnish. Thereafter, 165 patients who had undergone foot and ankle surgery completed a questionnaire set on two separate occasions. Analyses included testing of floor-ceiling effect, internal consistency, reproducibility, and validity. Results: Minor linguistic differences emerged during the translation. Some structural adjustments were made. The mean (SD) total VAS-FA score was 74 (23). In the three subscales, maximum scores were noted in 2-5% of the responses, and internal consis…

MalevalidityVisual Analog ScalejalkaterätleikkaushoitoRESPONSIVENESSpotilaslähtöisyys0302 clinical medicineInternal consistencyHealth Status IndicatorsOrthopedics and Sports MedicineReliability (statistics)Finlandta316reliabiliteetti030222 orthopedicsOUTCOMESPain Postoperativeta3141Middle Agedmedicine.anatomical_structureFemaleVAS-FAFoot (unit)Adultmedicine.medical_specialtyPsychometricsVisual analogue scalearviointimenetelmätCULTURAL-ADAPTATIONPain03 medical and health sciencesankleEXTREMITY FUNCTIONAL SCALESCOREmedicineQUALITYHumansPatient Reported Outcome MeasuresAged030203 arthritis & rheumatologyReproducibilityreliabilitybusiness.industryFootFoot and ankle surgeryReproducibility of ResultsLower Extremity Functional ScaleINSTRUMENTSTranslating3126 Surgery anesthesiology intensive care radiologynilkathoitotuloksetfootvaliditeettiPhysical therapyAnkleAnklebusinessFoot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons
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Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.

2017

Biological changes that occur during metastatic progression of breast cancer are still incompletely characterized. In this study, we compared intrinsic molecular subtypes and gene expression in 123 paired primary and metastatic tissues from breast cancer patients. Intrinsic subtype was identified using a PAM50 classifier and χ2 tests determined the differences in variable distribution. The rate of subtype conversion was 0% in basal-like tumors, 23.1% in HER2-enriched (HER2-E) tumors, 30.0% in luminal B tumors, and 55.3% in luminal A tumors. In 40.2% of cases, luminal A tumors converted to luminal B tumors, whereas in 14.3% of cases luminal A and B tumors converted to HER2-E tumors. We ident…

Mama -- Càncer -- Aspectes genètics0301 basic medicineCancer ResearchPathologyReceptor ErbB-2DiseaseTranscriptome0302 clinical medicineGene expressionSurvival outcomes Letrozole Concordance Predictor Disease Impact Brain Cells Women RiskSurvival outcomesDiseaseNeoplasm Metastasisskin and connective tissue diseasesRegulation of gene expressionAged 80 and overBrainCells WomenMiddle AgedPrognosisMetastatic breast cancerNeoplasm ProteinsGene Expression Regulation NeoplasticImpactOncology030220 oncology & carcinogenesisLetrozoleFemaleRiskAdultmedicine.medical_specialtymedicine.drug_classBreast NeoplasmsBiologyArticle03 medical and health sciencesBreast cancerConcordancemedicineBiomarkers TumorHumansGeneAgedEstrogensmedicine.disease030104 developmental biologyEstrogenNeoplasm Recurrence LocalTranscriptomePredictor
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Daily use of high-potency cannabis is associated with more positive symptoms in first-episode psychosis patients: The EU-GEI case-control study

2021

The work was supported by: Clinician Scientist Medical Research Council fellowship (project reference MR/M008436/1) to MDF; the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London at King’s College Hospital NHS Foundation Trust to DQ; DFG Heisenberg professorship (no. 389624707) to UR. National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and King’s College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. The EU-GEI Project is funded by t…

Marijuana AbuseIMPACTPoison controlCannabis usecannabis-associated psychosis0302 clinical medicineSCHIZOPHRENIASettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.health care economics and organizationsApplied PsychologyRISKOUTCOMESbiologyHuman factors and ergonomics/dk/atira/pure/subjectarea/asjc/2700/2738psychopathologyCannabis use; cannabis-associated psychosis; first episode psychosis; psychopathology; psychotic experiences; symptom dimensions3. Good healthPsychiatry and Mental healthSchizophreniaHEALTHPsychopathologyPsychosismedicine.medical_specialtyDISORDERSeducationsymptom dimensions03 medical and health sciencesInjury preventionfirst episode psychosismedicineHumanspsychotic experiencesPsychiatryABUSESettore MED/25 - PsichiatriaSUBSTANCE USEMETAANALYSISCannabisbusiness.industryCase-control studyOriginal Articlesmedicine.diseasebiology.organism_classification030227 psychiatrypsychotic experiencePsychotic Disordersfirst episode psychosiCase-Control StudiesONSETGene-Environment Interaction/dk/atira/pure/subjectarea/asjc/3200/3202Cannabisbusinesscannabis-associated psychosi030217 neurology & neurosurgery
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Consumer-Generated Reviews on Social Media and Brand Relationship Outcomes in the Fast-Food Chain Industry

2017

A number of studies agree on the fact that social media users tend to trust more the contents created by other users than those generated by companies’ marketing departments or advertising agencies. However, little is known regarding whether social media can actually enhance brand trust and other brand relationship outcomes that are deemed critical to the hospitality marketing literature. This paper seeks to offer some important insight on this issue by examining the impact of consumer-generated reviews on social media on four main pillars of the relationship marketing paradigm, i.e., satisfaction, trust, commitment, and loyalty. The inter-relationship between brand outcomes is also examine…

Marketingbusiness.industryBrand awarenessBrand relationship outcomes consumer-generated reviews fast-food chain brands social media communication university students05 social sciencesAdvertisingCustomer relationship managementManagement Information SystemsBrand managementBrand relationshipTourism Leisure and Hospitality Management0502 economics and business050211 marketingSocial mediaBrand equityMarketingbusinessComputingMilieux_MISCELLANEOUS050203 business & managementIntegrated marketing communicationsConsumer behaviour
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