Search results for "outer"

Sedimentary basins evolution and olistoliths formation: The case of Carpathian and Sicilian regions

2012

Abstract Comparative research carried out within two different basins, one in the Carpathians of Poland (Late Jurassic to Early Miocene) and another in the Apenninic-Maghrebian mountain chain of Sicily (Triassic-Miocene), indicate significant similarity not only in their evolution but also in the sedimentary features of horizons with olistoliths. The olistolith-bearing units are genetically related to stages of tectonic evolution and are independent of the size of the basins and of duration of these stages. However, the observed differences in composition and size of olistoliths suggested, among the others relationship with the size of source areas and thickness of their sedimentary cover.

Les populations périurbaines face à l'automobile en grande couronne francilienne

2007

The present article is attempting to identify if the automobile, which took part in development of periurban spaces but which causes strong disparities of mobility between households, according to their incomes and of their age, leads to exclude an increasing part of the population in this spaces. We looked more closely into not-motorized population but also motorized households, of modest income or older age, for which cost or physical requirements of automobile mobility are too high. Our results show that number of not-motorized households, most strongly marginalized, decrease in particular in periurban territories most dependent on car, in spite high level of unemployment and ageing of p…

Glaucomatous Maculopathy: Thickness Differences on Inner and Outer Macular Layers between Ocular Hypertension and Early Primary Open-Angle Glaucoma U…

2020

The purpose of this study was to compare the thickness of all inner and outer macular layers between ocular hypertension (OHT) and early primary open-angle glaucoma (POAG) using spectral domain optical coherence tomography (SD-OCT) 8 × 8 posterior pole algorithm (8 × 8 PPA). Fifty-seven eyes of 57 OHT individuals and fifty-seven eyes of 57 early POAG patients were included. The thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform and nuclear layer, photoreceptor layer (PRL) and retinal pigment epithelium were obtained in 64 cells for each macular layer and mean thickness of superior and inf…

A Series of Hadamard Designs with Large Automorphism Groups

2000

Abstract Whilst studying a certain symmetric (99, 49, 24)-design acted upon by a Frobenius group of order 21, it became clear that the design would be a member of an infinite series of symmetric (2q2 + 1, q2, (q2 − 1)/2)-designs for odd prime powers q. In this note, we present the definition of the series and give some information about the automorphism groups of its members.

The Efflux Pump MexXY/OprM Contributes to the Tolerance and Acquired Resistance of Pseudomonas aeruginosa to Colistin

2020

The intrinsic resistance of Pseudomonas aeruginosa to polymyxins in part relies on the addition of 4-amino-4-deoxy-l-arabinose (Ara4N) molecules to the lipid A of lipopolysaccharide (LPS), through induction of operon arnBCADTEF-ugd (arn) expression. As demonstrated previously, at least three two-component regulatory systems (PmrAB, ParRS, and CprRS) are able to upregulate this operon when bacteria are exposed to colistin. In the present study, gene deletion experiments with the bioluminescent strain PAO1::lux showed that ParRS is a key element in the tolerance of P. aeruginosa to this last-resort antibiotic (i.e., resistance to early drug killing). Other loci of the ParR regulon, such as th…

Ultrastructural evidence for protection of the outer hair cells of the inner ear during intense noise exposure by application of the organic calcium …

1999

Outer hair cells could be protected during intense noise exposure by the application of the calcium channel blocker diltiazem given before and after noise treatment. After various experimental approaches, the ultrastructural morphology was analysed for the different animal populations in the basal part of the second turn of the cochlea, which was the most destroyed area after an acute noise trauma caused by a gun shot (sound pressure at the ear drum 156 dB, frequency maximum between 4 and 6 kHz). Compared to untreated control specimens (experimental animal group I), the outer hair cells in the basal part of the second turn of the cochlea were mostly destroyed without any diltiazem applicati…

2021

Introduction Niemann-Pick type C (NPC) is a lysosomal storage disease that is progressive and life-limiting, with an estimated incidence of 1:120,000 live births. In addition to systemic manifestation with (hepato-)splenomegaly, there are a number of neurological manifestations (ataxia, dysarthria, dementia, cataplexy, epileptic seizures, and psychiatric disorders). Characteristic is vertical supranuclear gaze palsy, which is often overlooked. Early diagnosis and start of therapy improve quality of life. This study aimed to characterize oculomotor dysfunction of NPC patients, and to provide ophthalmologic data including retinal imaging. Methods Eighteen patients with biochemically or genet…

Atrophic Forms (Dry AMD)

2009

Atrophic form of “Dry AMD” is defined by areas of RPE atrophy, often resulting from regression of confluent soft drusen.

Clinical Features and Natural History of AMD on OCT

2009

Despite recent progress, age-related macular degeneration (AMD) remains the leading cause of vision loss in high-income countries, and its incidence appears to be increasing, probably due to longer life span and improved methods of detection.

Classic Choroidal Neovascularization

2009

Since Donald Gass’s pioneering work in 1967, which demonstrated the role of choroidal neovascularization (CNV) in wet (exudative) AMD, visible (classic) CNV, well demarcated and well-defined on fluorescein angiography, has become the most characteristic form of AMD.