Search results for "oxidation"

showing 10 items of 1913 documents

A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice

2020

We previously observed an unexpected fivefold (35 vs. 200 days) difference in the survival of respiratory chain complex III (CIII) deficient Bcs1lp.S78G mice between two congenic backgrounds. Here, we identify a spontaneous homoplasmic mtDNA variant (m.G14904A, mt-Cybp.D254N), affecting the CIII subunit cytochrome b (MT-CYB), in the background with short survival. We utilize maternal inheritance of mtDNA to confirm this as the causative variant and show that it further decreases the low CIII activity in Bcs1lp.S78G tissues to below survival threshold by 35 days of age. Molecular dynamics simulations predict D254N to restrict the flexibility of MT-CYB ef loop, potentially affecting RISP dyna…

DYNAMICSepistasisMale0301 basic medicineNon-Mendelian inheritanceMitochondrial DiseasesMetabolic disordersRespiratory chainGeneral Physics and AstronomyDISEASEmitokondriotauditElectron Transport Complex IIIMice0302 clinical medicineenergy metabolismCRYSTAL-STRUCTUREIRON-SULFUR PROTEINlcsh:ScienceMice KnockoutGeneticsmitokondrio-DNAMultidisciplinaryCYTOCHROME BC(1) COMPLEXCytochrome bQCytochromes bMitochondria3. Good healthFemaleRESPIRATORY-CHAINGRACILE SYNDROMEhenkiinjääminenOxidation-ReductionMitochondrial DNAMitochondrial diseaseScienceCongenicMolecular Dynamics SimulationBiologyDNA MitochondrialArticleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesaineenvaihduntahäiriötmedicinemetabolic disordersAnimalsMUTATIONSEpistasis GeneticEnergy metabolismGeneral ChemistryCytochrome b Groupmedicine.diseaseMice Inbred C57BL030104 developmental biologyCoenzyme Q – cytochrome c reductaseEpistasis1182 Biochemistry cell and molecular biologyATPases Associated with Diverse Cellular ActivitiesEpistasislcsh:QGUI MEMBRANE-BUILDERkoe-eläinmallitMetabolism Inborn Errors030217 neurology & neurosurgeryGENERATIONMolecular ChaperonesNature Communications
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Conservation and functional preservation of agri-food interest yeasts

2018

The use of yeasts in industry is inseparable from their ability to be produced and dehydrated. This dehydration process causes various dysfunctions in yeast cells that affect their functionality and viability. In order to protect yeasts from dehydration, food additives are often used as emulsifiers and antioxidants. However, yeasts are able to produce naturally protective substances, such as glutathione (GSH) and trehalose (TRE). In this context, three non-Saccharomyces (NS) strains, belonging to the different genera and species Torulaspora delbrueckii, Metschnikowia pulcherrima and Lachancea thermotolerans, were studied in this thesis. Despite the great interest aroused by their multiple a…

DehydrationYeastsLevuresOxidationNon-SaccharomycesTrehaloseDéshydratationOxydation[SDV.IDA] Life Sciences [q-bio]/Food engineeringGlutathioneGlutathion[SDV.BIO] Life Sciences [q-bio]/Biotechnology
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Influence of15N enrichment on the net isotopic fractionation factor during the reduction of nitrate to nitrous oxide in soil

2007

5 pages; International audience; Nitrous oxide, a greenhouse gas, is mainly emitted from soils during the denitrification process. Nitrogen stable-isotope investigations can help to characterise the N(2)O source and N(2)O production mechanisms. The stable-isotope approach is increasingly used with (15)N natural abundance or relatively low (15)N enrichment levels and requires a good knowledge of the isotopic fractionation effect inherent to this biological mechanism. This paper reports the measurement of the net and instantaneous isotopic fractionation factor (alpha(s/p) (i)) during the denitrification of NO(3) (-) to N(2)O over a range of (15)N substrate enrichments (0.37 to 1.00 atom% (15)…

DenitrificationAbundance (chemistry)[SDE.MCG]Environmental Sciences/Global ChangesNitrous Oxidechemistry.chemical_elementFractionationChemical FractionationGas Chromatography-Mass SpectrometryAnalytical ChemistrySoilchemistry.chemical_compoundNitrate[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/Geochemistry[ SDU.ENVI ] Sciences of the Universe [physics]/Continental interfaces environmentSoil Pollutants[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces environmentSpectroscopyNitratesNitrogen IsotopesChemistryOrganic ChemistrySubstrate (chemistry)Nitrous oxide[ SDU.STU.GC ] Sciences of the Universe [physics]/Earth Sciences/GeochemistryNitrogen[ SDE.MCG ] Environmental Sciences/Global ChangesEnvironmental chemistrySoil waterOxidation-ReductionRapid Communications in Mass Spectrometry
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Adsorption mechanism of arsenate by zirconyl-functionalized activated carbon

2007

Arsenate [As(V)] and arsenite [As(III)] sorption at the solid-water interface of activated carbon impregnated with zirconyl nitrate (Zr-AC) was investigated using X-ray absorption spectroscopy (XAS) and surface complexation modeling. The XAS data at the Zr K-edge suggest that the structure of the zirconyl nitrate coating is built from chains of edge-sharing ZrO8 trigonal dodecahedra bound to each other through two double hydroxyl bridges. The 8-fold coordination of each Zr atom is completed by four O atoms, which share a bit less than the two theoretically possible bidentate nitrate groups. On impregnation, two of the O atoms may lose their nitrate group and be transformed to hydroxyl group…

DenticityArsenitesSurface PropertiesInorganic chemistrychemistry.chemical_elementchemistry [Arsenites]Biomaterialschemistry.chemical_compoundColloid and Surface ChemistryAdsorptionOxidation statechemistry [Arsenates]medicineArsenicchemistry [Zirconium]ArseniteNitrateschemistry [Nitrates]Extended X-ray absorption fine structureSpectrum AnalysisX-Rayschemistry [Water]arsenic acidArsenateWaterCarbonchemistry [Carbon]Surfaces Coatings and FilmsElectronic Optical and Magnetic Materialsarsenitechemistryddc:540PotentiometryArsenatesAdsorptionZirconiumActivated carbonmedicine.drugJournal of Colloid and Interface Science
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Fast redox-triggered shuttling motions in a copper rotaxane based on a phenanthroline–terpyridine conjugate

2014

Fast shuttling motions in solution have been observed by cyclic voltammetry in a Cu(I/II)-based [2] rotaxane. In the reported system, the different coordination preferences of both copper oxidation states are exploited to promote the electrochemically-triggered gliding of the ring from a tetra to a pentacoordinated site and vice versa. The thread of this rotaxane consists of a tridentate 2,2':6',2''-terpyridine chelating unit directly bonded through its 5-position to the 3-position of the bidentate 1,10-phenanthroline unit. This distribution reduces to a minimum the distance between the two coordination sites and lessens the congestion around the tetrahedral environment. These two factors h…

DenticityRotaxaneRotaxanesPyridinesPhenanthrolineOrganic Chemistrychemistry.chemical_elementPhotochemistryElectrochemistryBiochemistryRedoxCopperKineticsMotionchemistry.chemical_compoundchemistryElectrochemistryPhysical and Theoretical ChemistryTerpyridineCyclic voltammetryOxidation-ReductionCopperPhenanthrolinesOrg. Biomol. Chem.
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Co-existence of ferro- and antiferromagnetic interactions in a hexanuclear mixed-valence CoIII2MnII2MnIV2 cluster sustained by a multidentate Schiff …

2019

The successful utilization of the “direct synthesis” approach yielded the unprecedented hexanuclear complex of formula [Co2MnII2MnIV2(L1)4Cl2(μ3-O)2(dmf)4]·2dmf (1) (H3L is the Schiff base derived from the condensation of salicylaldehyde and 3-aminopropane-1,2-diol). Single crystal X-ray analysis revealed that 1 crystallizes in the monoclinic system P21/c and it contains a rare mixed-valence {CoIII2MnII2MnIV2(μ2-O)8(μ3-O)2} core where all metal ions are linked through the phenolato and alkoxo groups of the L3− ligand. Besides the charge balance resulting from the X-ray structure, the oxidation state of the metal ions has been confirmed by XPS spectroscopy. Cryomagnetic studies indicate the …

DenticitySchiff baseValence (chemistry)Materials scienceSpin states010405 organic chemistryMetal ions in aqueous solution010402 general chemistry01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryOxidation state[CHIM]Chemical SciencesAntiferromagnetism[CHIM.COOR]Chemical Sciences/Coordination chemistryComputingMilieux_MISCELLANEOUSMonoclinic crystal systemDalton Transactions
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Dehydrogenative Anodic C−C Coupling of Phenols Bearing Electron‐Withdrawing Groups

2019

Abstract We herein present a metal‐free, electrosynthetic method that enables the direct dehydrogenative coupling reactions of phenols carrying electron‐withdrawing groups for the first time. The reactions are easy to conduct and scalable, as they are carried out in undivided cells and obviate the necessity for additional supporting electrolyte. As such, this conversion is efficient, practical, and thereby environmentally friendly, as production of waste is minimized. The method features a broad substrate scope, and a variety of functional groups are tolerated, providing easy access to precursors for novel polydentate ligands and even heterocycles such as dibenzofurans.

Denticityoxidation010405 organic chemistryChemistrySupporting electrolyteCommunicationC−C couplingoxygen heterocyclesSubstrate (chemistry)General Chemistry010402 general chemistryElectrochemistry01 natural sciencesEnvironmentally friendlyCombinatorial chemistryCommunicationsCatalysisCoupling reaction0104 chemical scienceschemistry.chemical_compoundElectrochemistry | Hot Paperelectrochemistrycross-couplingPolar effectPhenolsAngewandte Chemie International Edition
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Square wave voltammetric determination of the redox state of a reversibly oxidized/reduced depolarizer in solution and in solid state

2012

Abstract Square wave voltammetric measurements allows for determining the composition of system containing a reversibly reducible/oxidable electroactive species in two oxidation states. The method is based on recording the ratio of reverse to forward peak currents. That ratio can be correlated with the molar fraction of the oxidized (or reduced) form of the depolarizer. The method was compared with cyclic voltammetric methods suggested in literature and it was tested using Fe ( CN ) 6 3 - / Fe ( CN ) 6 4 - in solution phase. Application to solid state systems is illustrated by the dehydroindigo/indigo couple in synthetic Maya Blue-type specimens prepared from indigo plus different clays whe…

DepolarizerChemistryGeneral Chemical EngineeringInorganic chemistrySolid-stateAnalytical chemistrySquare waveMole fractionSolution phaseRedoxIndigoAnalytical ChemistryOxidation stateElectrochemistryJournal of Electroanalytical Chemistry
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2,4,6-Triphenylpyrylium Ion Encapsulated into Zeolite Y as a Selective Electrode for the Electrochemical Determination of Dopamine in the Presence of…

2002

2,4,6-Triphenylpyrylium ion immobilized inside the supercages of zeolite Y enhances by 1-2 orders of magnitude the response of electrochemical oxidation of dopamine in neutral aqueous media accompanied by a remarkable inhibition of post-electron-transfer reactions. The negative charge of the zeolite framework in which the 2,4,6-triphenylpyrylium ion is incorporated blocks the electrochemical oxidation of the negative ascorbate ion, enabling the determination of micromolar concentrations of dopamine in the presence of a large excess (10(3)-10(4) times) of ascorbate in phosphate buffer (pH 7.4). Under optimized conditions, linear calibration plots were obtained for a differential pulse detect…

Detection limitChemistryDopamineInorganic chemistryAscorbic AcidElectrochemistryAscorbic acidSensitivity and SpecificityOrders of magnitude (mass)Analytical ChemistryIonDopamineCalibrationElectrodeElectrochemistryZeolitesmedicineZeoliteElectrodesOxidation-ReductionPyransmedicine.drugAnalytical Chemistry
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A headspace solid-phase microextraction method of use in monitoring hexanal and pentane during storage: Application to liquid infant foods and powder…

2006

The determination of two secondary lipid oxidation compounds (hexanal and pentane) in liquid infant foods using a headspace solid-phase microextraction gas chromatographic (HS-SPME-GC) method has been developed and validated. The HS-SPME analytical conditions (fibre position, equilibration and sampling times) were selected. The analytical parameters of the method (linearity: hexanal from 2.48 to 84.78 ng/g, pentane from 6.21 to 79.55 ng/g; precision: hexanal 2.87%, pentane 2.343.46%; recovery: hexanal 106.60%, pentane 95.39%; detection limit: hexanal 3.63 ng and pentane 4.2 ng) demonstrate the usefulness of the method. Once optimized, the method was applied to liquid infant foods based on m…

Detection limitChromatographyInfants AlimentacióFood storageGeneral MedicineSolid-phase microextractionHexanalAnalytical ChemistryPentanechemistry.chemical_compoundchemistryLipid oxidationSolid phase extractionFood Science
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