Search results for "oxygen concentration"

showing 3 items of 43 documents

Normal Values of Oxygen Concentration in Human Blood

1984

Under physiological conditions, the oxygen supply as the product of O2-concentration (mlO2/dl; %(v/v)) and perfusion is influenced by many factors (cf. Fig. 1): perfusion on one hand, oxygen partial pressure (pO2; mmHg), haemoglobin (Hb) concentration (g/dl) and O2 binding power of Hb on the other hand. Under pathological conditions, oxygen supply disturbances are related to hypoxemia, i.e. reduction of O2-concentration in the blood. The differential diagnosis of hypoxemia includes normoxic, hypoxic and circulatoric disturbances of oxygen supply (cf. Fig. 1). Thus it is necessary to describe a NORMOXIC HYPOXEMIA (anemic or toxemic), a HYPOXIC HYPOXEMIA (decreased O2-concentration caused by …

medicine.medical_specialtyOxygen supplyHuman bloodChemistryHypoxia (environmental)Normal valuesPartial pressurerespiratory tract diseasesHypoxemiaInternal medicinemedicineCardiologyLimiting oxygen concentrationmedicine.symptomPerfusioncirculatory and respiratory physiology
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Managing Persistent Hypoxemia: what is new?

2017

Mechanical ventilation is the standard life-support technique for patients with severe acute respiratory failure. However, some patients develop persistent and refractory hypoxemia because their lungs are so severely damaged that they are unable to respond to the application of high inspired oxygen concentration and high levels of positive end-expiratory pressure. In this article, we review current knowledge on managing persistent hypoxemia in patients with injured lungs.

medicine.medical_specialtymedicine.medical_treatmentPhysiologyReviewmechanical ventilationGeneral Biochemistry Genetics and Molecular BiologyHypoxemia03 medical and health sciences0302 clinical medicineRefractorysevere acute respiratory failuremedicineAcute respiratory failureIn patientGeneral Pharmacology Toxicology and PharmaceuticsIntensive care medicineMechanical ventilationInspired oxygen concentrationhypoxemiaGeneral Immunology and Microbiologypersistent hypoxemiabusiness.industry030208 emergency & critical care medicineGeneral MedicineArticlesrespiratory tract diseases030228 respiratory systemRespiratory Problems in Critical Caremedicine.symptombusinessF1000Research
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Unusual oxygen binding behavior of a 24-meric crustacean hemocyanin.

2009

Abstract Hemocyanins from Crustacea usually are found as 1 × 6 or 2 × 6-meric assemblies. An exception is the hemocyanin isolated from thalassinidean shrimps where the main component is a 24-meric structure. Our analysis of oxygen binding data of the thalassinidean shrimp Upogebia pusilla based on a three-state MWC-model revealed that despite the 24-meric structure the functional properties can be described very well based on the hexamer as allosteric unit. In contrast to the hemocyanins from other thalassinidean shrimps the oxygen affinity of hemocyanin from U. pusilla is increased upon addition of l -lactate. A particular feature of this hemocyanin seems to be that l -lactate already enha…

medicine.medical_treatmentAllosteric regulationBiophysicschemical and pharmacologic phenomenaCooperativityRandom hexamerHemocyaninBiochemistryOxygen bindingAllosteric RegulationCrustaceaDecapodamedicineAnimalsHemocyanin; Crustacea; Allosteric model; Kinetics; Oxygen bindingMolecular BiologybiologyEcologyfungiHemocyaninbiology.organism_classificationAllosteric modelCrustaceanShrimpOxygenKineticsHemocyaninsBiophysicsLimiting oxygen concentrationOxygen bindingProtein BindingArchives of biochemistry and biophysics
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