Search results for "oxygen saturation"
showing 10 items of 72 documents
Signal processing procedures for the evaluation of the cardiovascular effects in the obstructive sleep apnea syndrome
2002
A new index, the cross-power index (CPI), is proposed to quantify the severity of obstructive sleep apnea syndrome (OSAS) in terms of its cardiovascular effects. On the basis of the influences that recurring drops in oxygen saturation have on systolic blood pressure variability of OSAS patients, CPI is defined as the integral of the cross-spectrum modulus between systolic blood pressure and oxygen saturation. In a test group of 22 subjects, CPI correctly identified all 15 OSAS patients included in the pool. Moreover, evaluation of CPI in six OSAS patients sleeping with and without a CPAP (continuous positive airway pressure) device demonstrated that CPAP treatment substantially reduced the …
Lacustrine, profundal meiobenthic oligochaetes as indicators of trophy and organic loading
1994
Meiobenthic and macrobenthic oligochaetes were collected from two depths in Lake Pajanne and examined together with environmental data in which two environmental gradients can be seen. Numbers of Piguetiella blanci, Aeolosoma quaternarium and Aeolosoma hemprichi were positively correlated with oxygen saturation and negatively correlated with total phosphorus and COD suggesting that these species are indicators of oligotrophic conditions. Numbers of Amphichaeta leydigii, Specaria josinae and Vejdovskyella comata were positively correlated with total phosphorus which implies that these species prefer eutrophic conditions. The last three species and Dero digitata showed positive correlations w…
Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups☆
2013
Background Fetal-to-neonatal transition is associated with oxidative stress. In preterm infants, immaturity of the antioxidant system favours supplemental oxygen-derived morbidity and mortality. Objectives To assess if prolonging in utero-like oxygenation during the fetal-to-neonatal transition limits oxidative stress in the lung and brain, improving postnatal adaptation of mice pups. Material and methods Inspiratory oxygen fraction (FiO2) in pregnant mice was reduced from 21% (room air) to 14% (hypoxia) 8–12 h prior to delivery and reset to 21% 6–8 h after birth. The control group was kept at 21% during the procedure. Reduced (GSH) and oxidized (GSSG) glutathione and its precursors [γ-glut…
Short-Term Outcomes of Patients With COVID-19 Undergoing Invasive Mechanical Ventilation: A Retrospective Observational Study From Wuhan, China.
2020
Background: COVID-19 has spread rapidly worldwide. Many patients require mechanical ventilation. The goal of this study was to investigate the clinical course and outcomes of patients with COVID-19 undergoing mechanical ventilation and identify factors associated with death. Methods: Eighty-three consecutive critically ill patients with confirmed COVID-19 undergoing invasive mechanical ventilation were included in this retrospective, single-center, observational study from January 31 to March 15, 2020. Demographic, clinical, laboratory, radiological, and mechanical ventilation data were collected and analyzed. The primary outcome was 28-day mortality after endotracheal intubation. The secon…
Reference values for mean overnight saturation in sleep apnoea – the European Sleep Apnoea Database (ESADA)
2020
Introduction: Normative values for mean overnight oxygen saturation during sleep in apnoea patients stratified for age, BMI, and sleep apnoea severity are lacking. Aim: To establish reference intervals for overnight mean saturation in a large sleep apnoea patient cohort. Methods: Mean overnight oxygen saturation was analysed in adult patients (n=23,220) from the European Sleep Apnoea Database (ESADA, 30 sleep centres, 18 European countries). Data were classified according to age, gender, BMI ( Results: Mean overnight saturation was 93.0% (95% confidence interval (CI) 92.9 to 93.1%). Age influenced the adjusted mean nocturnal saturation (93.6%, 93.2%, 92.9%, 92.5%, 92.2% and 91.9% for those …
Does Oxygen Concentration Used for Resuscitation Influence Outcome of Asphyxiated Newly Born Infants Treated With Hypothermia?
2006
To the Editor. — In a recent article, Rutherford et al1 describe the neuroprotective effect of whole-body cooling and selective head cooling in newly born infants suffering from hypoxic-ischemic encephalopathy. MRI studies of infants receiving either of these therapies showed a lesser degree of basal ganglia and thalamic lesions than nontreated controls, which correlates with a better neurologic prognosis. However, no description of the resuscitation maneuvers used is present in the article's “Patients and Methods” section. Thus, the authors do not include details on how many infants were given positive pressure ventilation and, especially, what concentration of oxygen was used, if oxygen s…
Therapy with non-invasive ventilation in patients with obstructive sleep apnoea: effects on atherogenic lipoprotein phenotype.
2009
Patients with obstructive sleep apnoea are at increased risk of atherosclerotic morbidity and mortality. Abnormalities in lipid metabolism that occur in response to chronic intermittent hypoxia in patients with sleep-disordered breathing may increase the cardiovascular risk in an already susceptible population. Atherogenic lipoprotein phenotype and small, dense LDL have an independent predictive role for future cardio- and cerebro-vascular events in patients with the metabolic syndrome. Therefore, testing the hypothesis that therapy of obstructive sleep apnoea may reduce atherogenic lipoprotein phenotype might have significant clinical implications. We suggest that abolition of obstructive …
Impact of increased mean arterial pressure on skin microcirculatory oxygenation in vasopressor-requiring septic patients: an interventional study
2019
Abstract Background Heterogeneity of microvascular blood flow leading to tissue hypoxia is a common finding in patients with septic shock. It may be related to suboptimal systemic perfusion pressure and lead to organ failure. Mapping of skin microcirculatory oxygen saturation and relative hemoglobin concentration using hyperspectral imaging allows to identify heterogeneity of perfusion and perform targeted measurement of oxygenation. We hypothesized that increasing mean arterial pressure would result in improved oxygenation in areas of the skin with most microvascular blood pooling. Methods We included adult patients admitted to the intensive care unit within the previous 24 h with sepsis a…
Analgesic and physiological effects in conscious sedation with different nitrous oxide concentrations
2015
Objectives: to study the physiological changes, as well as the psychosedative and analgesic effects of nitrous oxide, in experimental conditions. Study Design: 101 dental students volunteers participated in a single nitrous oxide sedation session without dental treatment. Signs and symptoms were registered during and after the procedure. Pulse rate and hemoglobin oxygen saturation were monitored at: 100 per cent O 2 , 30 per cent N 2 O, 50 per cent N 2 O and 5 minutes after 100 per cent O 2 . A Likert scale was used to evaluate pain perception. The analgesic effects of nitrous oxide were evaluated at: 30 per cent N 2 O, 50 per cent N 2 O, and five minutes postoperatively. Results: Pulse rat…
Theoretical Basis Versus Clinical Practice of Oxygen Parameters of Blood
1996
Under optimal conditions all oxygen parameters of human blood are defined at a theoretical basis, accepted and understood by the clinicians, measured correctly by instruments of different manufacturers and, therefore, leading to clear diagnoses for the patients.