6533b825fe1ef96bd12830a4

RESEARCH PRODUCT

Does Oxygen Concentration Used for Resuscitation Influence Outcome of Asphyxiated Newly Born Infants Treated With Hypothermia?

Máximo VentoIsabel IzquierdoRaquel EscrigJuan SastreJose ViñaPilar Saenz

subject

medicine.medical_specialtyHead coolingResuscitationmedicine.diagnostic_testbusiness.industryEncephalopathyHypothermiamedicine.diseasePulse oximetryAnesthesiaPediatrics Perinatology and Child HealthmedicineLimiting oxygen concentrationmedicine.symptomIntensive care medicinebusinessThalamic lesionsOxygen saturation (medicine)

description

To the Editor. — In a recent article, Rutherford et al1 describe the neuroprotective effect of whole-body cooling and selective head cooling in newly born infants suffering from hypoxic-ischemic encephalopathy. MRI studies of infants receiving either of these therapies showed a lesser degree of basal ganglia and thalamic lesions than nontreated controls, which correlates with a better neurologic prognosis. However, no description of the resuscitation maneuvers used is present in the article's “Patients and Methods” section. Thus, the authors do not include details on how many infants were given positive pressure ventilation and, especially, what concentration of oxygen was used, if oxygen saturation was controlled by pulse oximetry within physiologic limits, or if blood gases were determined once the resuscitation procedures were concluded …

https://doi.org/10.1542/peds.2005-2804