Search results for "parametri"
showing 10 items of 1144 documents
A multiparametric magnetic resonance imaging-based virtual reality surgical navigation tool for robotic-assisted radical prostatectomy
2019
Objective Increased computational power and improved visualization hardware have generated more opportunities for virtual reality (VR) applications in healthcare. In this study, we test the feasibility of a VR-assisted surgical navigation system for robotic-assisted radical prostatectomy. Material and methods The prostate, all magnetic resonance imaging (MRI) visible tumors, and important anatomic structures like the neurovascular bundles, seminal vesicles, bladder, and rectum were contoured on a multiparametric MRI using an in-house segmentation software. Three-dimensional (3-D) VR models were rendered and evaluated in a side room of the operating room. While interacting with the VR platfo…
Early developmental alterations of low-Mg2+ -induced epileptiform activity in the intact corticohippocampal formation of the newborn mouse in vitro.
2005
Abstract The generation, propagation and pharmacological properties of low-Mg 2+ -induced epileptiform activity were examined in the intact corticohippocampal formation (CHF) of the newborn (P0–4) mouse in vitro. Multi-site field potential recordings in dentate gyrus (DG), CA3, CA1, entorhinal cortex (EC) and temporal cortex (TC) revealed in 0.2 mM Mg 2+ -containing ACSF a stable pattern of spontaneous epileptiform activity consisting of recurrent ictal-like events (ILEs) and interictal events (IEs). Although this activity could be consistently observed as early as P0, ILEs were smaller in amplitude, less frequent and showed a slower onset in P0–2 as compared to P3–4 animals. In all age gro…
Post‐COVID ‐19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound
2021
OBJECTIVES: This study aimed to define patterns of liver injury after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using multiparametric ultrasound (mpUS) in a variable patient population with differing severities of COVID-19. METHODS: Ninety patients were enrolled into the study: 56 had SARS-CoV-2 3-9 months prior to enrolment; 34 served as a clinically healthy control group. All patients underwent an mpUS evaluation of the liver (elastography, dispersion and attenuation imaging). Seventy-six patients had abdominal magnetic resonance (MR) and noncontrast enhanced thoracic computed tomography (CT) scans performed at the same day. All patients were screened for bioc…
Changes of the air quality data structures during the Covid-19 pandemic
2021
Maģistra darba “Gaisa kvalitātes datu struktūras izmaiņas Covid-19 pandēmijas ietekmē” aktualitāte saistāma ar faktu, ka Latvijas kontekstā Covid-19 un atmosfēras gaisa kvalitāte nav plaši pētīta no datu struktūras izmaiņu viedokļa. Darba mērķis ir noskaidrot kādas izmaiņas vērojamas atmosfēras piesārņojuma datu struktūrā kā ietekmējošo faktoru izvēloties COVID-19 globālās pandēmijas ietekmi. Covid-19 pandēmijas ierobežošanai visā pasaulē tika noteikti dažādi ierobežojumi, kā rezultātā stājoties spēkā ierobežojumiem gaisa piesārņojošo vielu koncentrācijas daudzās valstīs samazinājās. Darba rezultāti nav viennozīmīgi vērtējami un katrai pilsētai ir savas atšķirības. Ir pamanāmas arī kopīgas …
Biogēno procesu modelēšanas iespēju novērtējums pāraugušās audzēs
2019
Maģistra darbā izstrādāts biogēno procesu norises modelis neskartās, pāraugušās priežu audzēs, kuru iespējams izmantot procesu paredzēšanai nākotnē. Izstrādātais modelis pilnveido zināšanas par mežaudzē notiekošajiem procesiem un atsevišķiem ietekmējošiem faktoriem. Simulācijās izmantoti tādi biogēniskie faktori kā temperatūras, nokrišņu, vēja ātruma un kukaiņu nodarītā kaitējuma izvērtējums. Simulāciju scenāriji izstrādāti pāraugušām priežu audzēm Latvijas teritorijā, kuri izvietoti katrs savā reģionā (kopā 4 pētījumu pilotteritorijas) un atrodas ne tālāk par 50 km no meteoroloģisko novērojumu stacijas. Iegūtie rezultāti liecina, ka pētāmajās mežaudzēs būtiskākais ir tās vecums, bet apskat…
Uniformization of two-dimensional metric surfaces
2014
We establish uniformization results for metric spaces that are homeomorphic to the Euclidean plane or sphere and have locally finite Hausdorff 2-measure. Applying the geometric definition of quasiconformality, we give a necessary and sufficient condition for such spaces to be QC equivalent to the Euclidean plane, disk, or sphere. Moreover, we show that if such a QC parametrization exists, then the dilatation can be bounded by 2. As an application, we show that the Euclidean upper bound for measures of balls is a sufficient condition for the existence of a 2-QC parametrization. This result gives a new approach to the Bonk-Kleiner theorem on parametrizations of Ahlfors 2-regular spheres by qu…
Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence
2019
Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 µ
Modelización de riesgos climáticos y sistemas de vigilancia y alerta en la Comunitat Valenciana
2013
El primer objetivo de esta Tesis está relacionado con el desarrollo e implementación de diferentes sistemas de vigilancia y alerta para el territorio de la Comunitat Valenciana: un sistema de predicción meteorológica en tiempo real basado en el modelo atmosférico de mesoescala Regional Atmospheric Modeling System (RAMS) y un sistema de previsión del Índice UV (UVI), basado en el modelo Santa Barbara DISORT Atmospheric Radiative Transfer (SBDART). Además, se propone una metodología que proporciona un entorno computacional adecuado para la administración y coordinación de los diferentes procesos implicados en ambos sistemas de vigilancia. La principal mejora de la predicción UVI es la utiliza…
Transcriptional profiles from patients with dystrophinopathies and limb girdle muscular dystrophies as determined by qRT-PCR.
2003
Mutations in genes coding for the dystrophin-glycoprotein complex (DGC) cause inherited muscular dystrophies (MD), including Morbus Duchenne (DMD) and M. Becker (BMB) as well as limb-girdle muscular dystrophies (LGMD). New insights into the pathophysiology of the dystrophic muscle, the identification of compensatory mechanisms and additional proteins interacting with dystrophin are essential for developing new treatments. In order to define molecular mechanisms induced by lack of dystrophin and the subsequent counter-regulatory transcriptional response of degenerating muscle fibres, we have investigated the mRNA expression of 19 functionally linked genes in biopsies of patients with MD by m…