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showing 10 items of 15327 documents
The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms.
2015
Objectives:\ud The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.\ud \ud Methods:\ud Pharmacological manipulation of the activity of CRF receptors, CRF1 and CRF2, was performed in 3T3L1 white pre-adipocytes and T37i brown pre-adipocytes during in vitro differentiation. The expression of genes of the CRF/urocortin system and of markers of white and brown adipocytes was evaluated along with mitochondrial biogenesis and cellular oxygen consumption. Metabolic evaluation of corticosterone-deficient or supplemented Crhr1-null (Crhr1−/−) mice and their wild-type controls was performed alo…
Toward a link between brain plasticity and satiety
2021
International audience
New developments in the pathogenesis of obesity-induced hypertension
2015
Obesity is a disorder that develops from the interaction between genotype and environment involving social, behavioral, cultural, and physiological factors. Obesity increases the risk for type 2 diabetes mellitus, hypertension, cardiovascular disease, cancer, musculoskeletal disorders, chronic kidney and pulmonary disease. Although obesity is clearly associated with an increased prevalence of hypertension, many obese individuals may not develop hypertension. Protecting factors may exist and it is important to understand why obesity is not always related to hypertension. The aim of this review is to highlight the knowledge gap for the association between obesity, hypertension, and potential …
Odorants' metabolism in Human: a critical role in odor perception revealed
2018
Le petit appétit du grand âge
2018
National audience
L'alimentation des seniors : bien manger pour bien vieillir
2022
Dénutrition et alimentation des personnes âgées
2023
The relationship between working alliance with peer mentors and eating psychopathology in a digital 6‐week guided self‐help intervention for anorexia…
2021
Objective: The quality of working alliance (WA) is associated with treatment outcomes across several types of psychiatric disorders and psychological interventions. This study examined the role of WA with peer mentors (people with lived experience of illness) and student mentors (graduated psychology students) in a 6-week, digital, guided self-help (GSH) intervention for anorexia nervosa. Method: Ninety-nine patients rated weekly, for 6 weeks: (a) eating psychopathology using the short version of the Eating Disorder Examination Questionnaire (EDE-QS) and (b) WA with a student mentor (n = 14) or a peer mentor (n = 10). WA was assessed by asking patients the extent to which they felt comforta…
Motivational predictors of students' participation in out-of-school learning activities and academic attainment in science : An application of the tr…
2018
Abstract Given the shortfall in students studying science, promotion of motivation and engagement in science education is a priority. The current study applied the trans-contextual model to study the motivational predictors of participation in science learning activities in secondary-school students . In a three-wave design, secondary-school students completed measures of perceived autonomy support, autonomous and controlled motivation, social-cognitive beliefs (attitudes, subjective norms, perceived control), intentions, and self-reported participation in out-of-school science learning activities. Five-weeks later, students self-reported their science learning activities. Students' science…
Grit and self-discipline as predictors of effort and academic attainment
2019
Background: Beyond ability, traits related to perseverance, such as grit and self‐discipline, are associated with adaptive educational outcomes. Few studies have examined the independent effects of these traits on outcomes and the mechanisms involved. - Aims: This study estimated parameters of a process model in which grit‐perseverance of effort (grit‐effort) and consistency of interest (grit‐interest) dimensions and self‐discipline were independent predictors of students’ science grades. The effect of the grit‐effort on grades was expected to be mediated by students’ self‐reported effort on optional out‐of‐school science learning activities. - Sample: Secondary school students (N = 110) ag…