Search results for "phosphate"
showing 10 items of 1874 documents
Feasible Low-Phosphorus Dietary Patterns in Maintenance Hemodialysis Patients: Need for Original Research
2020
Introduction The standard low-phosphorus diet restricts pulses, nuts, and whole grains and other high phosphorus foods to control hyperphosphatemia. We conducted a randomized controlled trial to evaluate the effectiveness, safety, and tolerability of the modified diet, which introduced some pulses and nuts, increased the use of whole grains, increased focus on the avoidance of phosphate additives, and introduced the prescription of low-biological-value protein such as bread. Methods We conducted a multicenter, pragmatic, parallel-arm, open-label, randomized controlled trial of modified versus standard diet in 74 adults on hemodialysis with hyperphosphatemia over 1 month. Biochemistry was as…
High accessibility and chemical homogeneity in mesoporous materials: silicas, gold-containing composites and phosphates
2015
El trabajo recopilado en esta tesis está basado en la formación de materiales mesoporosos y sus posibles usos como catalizadores. Este trabajo se ha estructurado en cuatro partes diferenciadas. En primer lugar se presenta una breve introducción a los materiales mesoporosos revisando su evolución en la historia, los diferentes métodos de síntesis, su versatilidad en cuanto a funcionalización y aplicaciones y acabando con un repaso al trabajo realizado en el grupo de investigación. El segundo capítulo está centrado en el mejor conocimiento de la sílice UVM-7, un material mesoporoso de carácter bimodal desarrollado por el grupo. En primer lugar se estudia en detalle la estructura del material …
Facile and efficient chemical functionalization of aliphatic polyesters by cross metathesis
2016
International audience; An effective preparation of new tailor-made macromolecular materials via a combination of two (atom-efficient) catalytic transformations is reported. First, new aliphatic polyesters with alternated composition have been prepared using a salen aluminum catalyst system. Next, the pendant vinyl moieties in those copolymers have been selectively transformed into various functional groups by metathesis in the presence of homogeneous Grubbs catalysts. The latter metathesis reaction has been optimized in terms of catalytic activity and selectivity, to define the conditions for an effective and safe procedure that does not affect the macromolecular architecture. All polymer …
High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor
2017
N-Alkyl ammonium resorcinarenes selectively bind pyrophosphate in pure water with an exceptionally high binding constant of up to 1.60 × 107 M–1, three orders of magnitude higher than ATP.
Differential detection and quantification of cyclic AMP and other adenosine phosphates in live cell
2017
A new naphthol-based rhodamine derivative (NpRD) has been developed for the selective and differential detection of adenosine 3′,5′-cyclic monophosphate (cAMP) and adenosine phosphates (APs) (ATP, ADP, and AMP) from other nucleotides. The simple detection and quantification of cAMP in human blood cells and in other samples based on the ‘turn on’ fluorescence properties of this chemosensor through colorimetry or fluorometry makes it unique for probable application in high throughput screening. peerReviewed
Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters
2002
In the present study, we addressed the question of a putative relevance of Rho proteins in tumour progression by analysing their expression on protein and mRNA level in breast tumours. We show that the level of RhoA, RhoB, Rac1 and Cdc42 protein is largely enhanced in all tumour samples analysed (n=15) as compared to normal tissues originating from the same individual. The same is true for 32P-ADP-ribosylation of Rho proteins which is catalysed by Clostridium botulinum exoenzyme C3. Also the amount of Rho-GDI and ERK2 as well as the level of overall 32P-GTP binding acvitity was tumour-specific elevated, yet to a lower extent than Rho proteins. Although the amount of Rho proteins was enhance…
Cubic and Spirocyclic Radicals Containing a Tetraimidophosphate Dianion [P(NR)3(NR‘)]•2-
2005
The reaction of Cl3PNSiMe3 with 3 equiv of LiHNR (R = iPr, Cy, tBu, Ad) in diethyl ether produces the corresponding tris(amino)(imino)phosphoranes (RNH)3PNSiMe3 (1a, R = iPr; 1b, R = Cy; 1c, R = tBu; 1d, R = Ad); subsequent reactions of 1b−d with nBuLi yield the trilithiated tetraimidophosphates {Li3[P(NR)3(NSiMe3)]} (2a, R = Cy; 2b, R = tBu; 2c, R = Ad). The reaction of [(tBuNH)4P]Cl with 1 equiv of nBuLi results in the isolation of (tBuNH)3PNtBu (1e); treatment of 1e with additional nBuLi generates the symmetrical tetraimidophosphate {Li3[P(NtBu)4]} (2d). Compounds 1 and 2 have been characterized by multinuclear (1H, 13C, and 31P) NMR spectroscopy; X-ray structures of 1b,c were also obtai…
KOSMOS 2017 Peru Side Experiment: nutrients, phytoplankton abundances, enzyme rates, photophysiology
2022
This data was collected during an short-term incubation experiment in March 2017 that investigated the response of a surface plankton community to upwelling. This experiment was carried in the framework of the SFB754-funded KOSMOS mesocosm study that took place in La Punta, Callao, Peru between February-April 2017. A total of six different treatments were used to disentangle chemical and biological characteristics of deep water that influence surface plankton blooms: 2 different deep water sources with different nutrient concentrations; 3 treatments to distinguish the effects of inorganic nutrients, organic nutrients and deep water microbial populations. Measured variables include inorganic…
Ammonium phosphate method in preservation of marble artifact
2022
In questo lavoro si studiano gli effetti dell'uso del fosfato di ammonio come consolidante nell'ambito del restauro e del consolidamento di una colonna binata nel lato est del chiostro di Santa Maria La Nova a Monreale, Palermo, Italia This paper studies the effects of using ammonium phosphate as a consolidating agent in the restoration and consolidation of a binata column in the east side of the cloister of Santa Maria La Nova in Monreale, Palermo, Italy
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin s…
1994
Cytotoxic necrotizing factor type 2 (CNF2) produced by Escherichia coli strains isolated from intestinal and extraintestinal infections is a dermonecrotic toxin of 110 kDa. We cloned the CNF2 gene from a large plasmid carried by an Escherichia coli strain isolated from a lamb with septicemia. Hydropathy analysis of the deduced amino acid sequence revealed a largely hydrophilic protein with two potential hydrophobic transmembrane domains. The N-terminal half of CNF2 showed striking homology (27% identity and 80% conserved residues) to the N-terminal portion of Pasteurella multocida toxin. Methylamine protection experiments and immunofluorescence studies suggested that CNF2 enters the cytosol…