Search results for "physiologic"
showing 10 items of 2593 documents
Stability in physiological saline of intravenous busulfan in a polyolefin pack
2008
Abstract Introduction Although it has been used orally, the variability in its absorption and the risk of causing vomiting has lead to a push towards the intravenous use of busulfan. This study looks at the stability of 60 mg of busulfan, in fixed volumes of 250 mL (0.24 mg/mL) and 500 mL (0.12 mg/mL) of physiological saline and different conservation conditions, in a new plastic pack made from polyolefin/polyamide laminates. Material and methods High-performance liquid chromatography with ultraviolet detection was used to determine the concentration of busulfan derivate with sodium diethyldithiocarbamate trihydrate. Stability was assessed for both concentrations; refrigerated and at room t…
Orchestin, a calcium-binding phosphoprotein, is a matrix component of two successive transitory calcified biomineralizations cyclically elaborated by…
2003
Orchestia cavimana is a crustacean that cyclically replaces its calcified cuticle during molting cycles in order to grow. Its terrestrial way of life requires storage of calcium during each premolt period, as calcareous concretions, in tubular diverticula of the midgut. During the postmolt period the stored calcium is reabsorbed and is translocated through the storage organ epithelium as calcified small spherules. In a previous study, we sequenced and characterized a remarkable component of the organic matrix of the premolt storage structures, Orchestin, which is a calcium-binding phosphoprotein. In this paper, we analyzed the spatiotemporal expression of the orchestin gene by Northern blot…
Designing a Low-Fat Food Packaging: Comparing Consumers’ Responses in Virtual and Physical Shopping Environments
2021
This paper aims to test to what extent emotional responses towards a low-fat product presented virtually converge with emotional responses toward this product when presented physically. Second, we want to probe if low-order emotions (physiological/unconscious responses) and high-order emotions (cognitive/conscious responses) converge to explain healthy product choices. To this end, 83 young participants were engaged in our experiment. Two packaging design variables were manipulated with the help of a real company (the color and the message), so that six different packages were created. Two different buying contexts were simulated: A virtual context and a physical context. Physiological resp…
Severe Perinatal Hypoxic-Ischemic Brain Injury Induces Long-Term Sensorimotor Deficits, Anxiety-Like Behaviors and Cognitive Impairment in a Sex-, Ag…
2019
Perinatal brain injury (PBI) leads to neurological disabilities throughout life, from motor deficits, cognitive limitations to severe cerebral palsy. Yet, perinatal brain damage has limited therapeutic outcomes. Besides, the immature brain of premature children is at increased risk of hypoxic/ischemic (HI) injury, with males being more susceptible to it and less responsive to protective/therapeutical interventions. Here, we model in male and female C57BL/6 mice, the impact of neonatal HI and the protective effects of neonatal handling (NH), an early life tactile and proprioceptive sensory stimulation. From postnatal day 1 (PND1, modeling pre-term) to PND21 randomized litters received either…
P300 amplitudes in the Concealed Information Test are less affected by depth of processing than electrodermal responses
2012
The Concealed Information Test (CIT) has been used in the laboratory as well as in field applications to detect concealed crime related memories. The presentation of crime relevant details to guilty suspects has been shown to elicit enhanced N200 and P300 amplitudes of the event-related brain potentials (ERPs) as well as greater skin conductance responses (SCRs) as compared to neutral test items. These electrophysiological and electrodermal responses were found to incrementally contribute to the validity of the test, thereby suggesting that these response systems are sensitive to different psychological processes. In the current study, we tested whether depth of processing differentially af…
The Copper-microRNA Pathway Is Integrated with Developmental and Environmental Stress Responses in Arabidopsis thaliana
2021
As an essential nutrient, copper (Cu) scarcity causes a decrease in agricultural production. Cu deficiency responses include the induction of several microRNAs, known as Cu-miRNAs, which are responsible for degrading mRNAs from abundant and dispensable cuproproteins to economize copper when scarce. Cu-miRNAs, such as miR398 and miR408 are conserved, as well as the signal transduction pathway to induce them under Cu deficiency. The Arabidopsis thaliana SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE (SPL) family member SPL7 binds to the cis-regulatory motifs present in the promoter regions of genes expressed under Cu deficiency, including Cu-miRNAs. The expression of several other SPL transcription f…
Effects of Transcranial Direct Current Stimulation on Brain Networks Related to Creative Thinking
2020
AbstractHuman creative thinking is unique and capable of generating novel and valuable ideas. Recent research has clarified the contribution of different brain networks (default mode network, DN; executive control network; salience network) to creative thinking. However, the effects of brain stimulation on brain networks during creative thinking and on creative performance have not been clarified. The present study was designed to examine the changes in functional connectivity (FC) and effective connectivity (EC) of the large-scale brain network, and the ensuing changes in creative performance, induced by transcranial direct current stimulation (tDCS). Fourteen healthy male students underwe…
Understanding the role of cross-language transfer of phonological awareness in emergent Hindi–English biliteracy acquisition
2022
AbstractThis study examined within and cross-language relations, and specifically, the role of phonological awareness (PA) skills in reading among young Hindi-speaking children (L1) who were learning to read English (L2) in Delhi, India. Data was collected from 143 children in Grades 1 and 2 using measures validated for this population. The analyses examined the associations between L1 and L2 PA and decoding, both within and across the two languages. The results showed that PA skills within each language significantly predicted decoding in that language. Furthermore, there was evidence of cross-language transfer with Hindi PA significantly predicting English word reading even after controll…
Teachers' daily physiological stress and positive affect in relation to their general occupational well‐being
2023
Background Teachers' stress, affect and general occupational well-being influence their teaching and their students. However, how teachers' daily physiological stress and positive affect are related in the classroom is unknown. To reduce teachers' stress and enhance their positive affect, it is crucial to understand how occupational well-being relates to stress and affect. Aim The aim of the study was to examine the relationships between teachers' daily physiological stress and positive affect in authentic classroom settings and the roles played by teachers' self-efficacy beliefs, perceptions of school climate and burnout symptoms in daily stress and affect. Sample The sample consisted of 4…
Iontophoresis: electrorepulsion and electroosmosis.
2000
Over the last 10-15 years, the electrical enhancement of drug delivery across the skin has undergone intense investigation. During this period, considerable amounts of experimental data have been generated, and the successful enhancement of a diverse array of molecules has been achieved. Indeed, the commercial exploitation of the method can be envisaged within the next few years. Despite this progress, however, the mechanistic understanding of iontophoresis remains a challenging scientific question that is yet to be fully resolved. The routes of permeation under the influence of an applied electrical potential, and the molecular interactions of the transporting drug with these pathways, hav…