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Chronic Mesenteric Ischemia: Critical review and guidelines for management
2011
Background CMI is caused by chronic occlusive disease of mesenteric arteries. In such an uncommon disease, clear recommendations are strongly needed. Unfortunately, treatment options for symptomatic CMI are still controversial and no guidelines exist. Methods A systematic literature review of the last 25-years was conducted through MEDLINE, Embase, and Cochrane Review/Trials register to identify studies reporting on CMI treatment with more than 10 patients. Primary outcomes were perioperative mortality and morbidity rates. Secondary outcomes were survival rates, primary and secondary patency rates, vessels treated, CMI recurrence, follow-up (FU), technical success (TS), and in-hospital leng…
Scholarly publishing depends on peer reviewers
2018
The peer-review crisis is posing a risk to the scholarly peer-reviewed journal system. Journals have to ask many potential peer reviewers to obtain a minimum acceptable number of peers accepting reviewing a manuscript. Several solutions have been suggested to overcome this shortage. From reimbursing for the job, to eliminating pre-publication reviews, one cannot predict which is more dangerous for the future of scholarly publishing. And, why not acknowledging their contribution to the final version of the article published? PubMed created two categories of contributors: authors [AU] and collaborators [IR]. Why not a third category for the peer-reviewer? published
Sequence of deformation in the sicilidi units (northern sicilian chain)
2004
The foredeep deposits of Northern Sicily, indicated as Sicilidi units, have undergone different deformations' since Oligocene time. The resulting tectonic Structures, analysed in several outcrops in the Eastern Madonie Mts, are 1 cm-to- 100 m in scale and are similar to the larger structures forming the Sicily belt, allowing for scale extrapolation. Also the overprinting relationships of the minor structures recorded in the so-called Tufiti di Tusa reflect the sequence of fault activation which determined the present-day geometry of the tectonic units, suggesting that the tectonic evolution of the foreland basin developed during the stacking of the Maghrebide fold-and-thrust belt. The overp…
Hyperosmolar therapy for acute brain injury: study protocol for an umbrella review of meta-analyses and an evidence mapping
2020
Introduction Acute brain injury is a challenging public health problem worldwide. Elevated intracranial pressure is a common complication after acute brain injury. Hyperosmolar therapy is one of the main therapeutic strategies for the management of intracranial hypertension. This study protocol outlines an umbrella review of meta-analyses which will investigate the benefits and harms of hyperosmolar therapy routinely used for the management of acute brain injury in the intensive care. Methods and analysis We will search PubMed/MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews. We will include meta-analyses of primary research studies (eg, randomised controlled trials, observat…
Zn2+ and Cu2+ complexes of a fluorescent scorpiand-type oxadiazole azamacrocyclic ligand: crystal structures, solution studies and optical properties
2020
A ligand comprised of a macrocyclic pyridinophane core having a pendant arm containing a secondary amine group linked through a methylene spacer to a pyridyl–oxadiazole–phenyl (PyPD) fluorescent system has been prepared (L). The crystal structures of [ZnL](ClO4)2 and [CuL](ClO4)2 show that M2+ is coordinated to all the nitrogen atoms of the macrocyclic core, the secondary amine of the pendant arm and the nitrogen atom of the pyridine group of the fluorescent moiety, the latter bond being clearly weaker than the one with the pyridine of the macrocycle. Solution studies showed the formation of a highly stable Cu2+ complex with 1 : 1 stoichiometry, whereas with Zn2+ least stable complexes were…
NONEQUILIBRIUM PHENOMENA AND METASTABILITY IN MESOSCOPIC AND QUANTUM SYSTEMS
2020
Here we summarize some relevant results related to nonequilibrium phenomena in mesoscopic and quantum systems. A common phenomenon in the dynamics of out-of-equilibrium systems is the metastability, and the problem of the lifetime of metastable states involves fundamental aspects of nonequilibrium statistical mechanics. Metastability (see Fig. 1) is a signature of a first order phase transition, often characterized by a long-living metastable state. In particular, the stability of a metastable state can be enhanced by Gaussian and non-Gaussian noise sources. This counterintuitive effect has been found in different physical areas, ranging from spintronics, aggregation kinetics of Brownian pa…
Divu parastās egles Picea abies (L.) H. Karst. audžu ar atšķirīgu sākotnējo biezumu augšanas dinamikas atšķirības
2021
Parastā egle ir otrā visizplatītākā koku suga Latvijā. Sākotnējais stādījuma biezums viennozīmīgi ietekmē egļu audžu attīstības dinamiku. Ir svarīgi izvērtēt ģenētisko un klimatisko faktoru ietekmi uz koku radiālo augšanu un attīstību zema sākotnējā biezuma audzēs. Latvijā nav veikti pētījumi par klimatisko un ģenētisko faktoru ietekmi uz ekstremāli zemu sākotnēja stādījuma biezuma audžu attīstību 50 gadus vecās audzēs. Pētījumam iegūti dati no divām 50 gadus vecām parastās egles audzēm ar atšķirīgu sākotnējo stādījuma biezumu, no kurām vienai bija pieejama informācija par klonu izcelsmi. Pētījumam ievākti individuālu koku urbumu paraugi un veikta taksācija abām audzēm un kloniem 2018. gada…
Consequences of analgesics use in early pregnancy: Results of tests on mice.
2019
International audience; Self-medication during pregnancy continues to be an issue in developing countries due topoor medical education. The most commonly used drugs are analgesics, mainlyacetaminophen (paracetamol, APAP) and, to a lesser extent, ketoprofen (KPF). The aim of thestudy was to establish whether there are consequences of accidental use of these two drugsduring early embryogenesis. The experimental study was performed on 30 pregnant whitemice, divided into three groups: a first group to which APAP was administered, a secondgroup to which KPF was administered, and group 3 as a control group. At delivery, the babymice were examined, and after their first parturition, they were take…
Análisis del perfil de expresión de microRNAs en tejido embrionario sano y ectópico
2016
La placentación es un proceso fundamental en el éxito de la reproducción, sometido a una estrecha regulación donde el trofoblasto juega una función clave. Este proceso se realiza adecuadamente gracias a la relación estrictamente regulada entre los tejidos materno-fetales, donde intervienen multitud de moléculas y receptores; por tanto es necesario un correcto desarrollo de dicho proceso para asegurar una gestación a término saludable, y la invasión anómala del trofoblasto conducirá a un gran abanico de complicaciones, entre ellas el embarazo ectópico. El proceso de placentación está alterado en las gestaciones ectópicas, produciéndose la implantación fuera de la cavidad endometrial. Las alt…
Fabricación, caracterización, modelado y propuesta de aplicabilidad de sensores magnetorresistivos de efecto túnel para medición de potencia y sensor…
2015
En el capítulo 1 se describen los fundamentos teóricos a utilizar para los análisis y estudios a realizar más adelante, así como una breve explicación del estado de la técnica que es el estado actual de la tecnología al momento de redacción de la tesis. La introducción se divide en la tecnología magnetorresistiva, definiendo qué es y los efectos magnetorresistivos que existen así como su aplicación aeroespacial y modelización fraccional. A continuación se presenta el procesamiento digital de datos y las redes de sensores tratando un poco sobre los protocolos de comunicación formatos y aplicación de la transformada digital de Fourier. En el capítulo 2 se aborda la microfabricación de los sen…