Search results for "pic"

Nitrate and nitrite in the diet: How to assess their benefit and risk for human health

2015

Nitrate is a natural constituent of the human diet and an approved food additive. It can be partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases blood pressure. This effect is associated with a reduced risk regarding cardiovascular disease, myocardial infarction, and stroke. Moreover, dietary nitrate has been associated with beneficial effects in patients with gastric ulcer, renal failure, or metabolic syndrome. Recent studies indicate that such beneficial health effects due to dietary nitrate may be achievable at intake levels resulting from the daily consumption of nitrate-rich vegetables. N-nitroso compounds are endogenously formed in humans. However…

Una possible intepretazione junghiana dell’insight di Kekulé

2012

Entropic model application to identify cross-sectional flow effect on velocity distribution in a large amplitude meandering channel

2020

Abstract Literature shows the application of the entropy concept in open channels flow. No existing research has been addressed to the application of the entropy concept for evaluating the effect of secondary flow which especially develops in curved channels. The purpose of this paper is to explore the possibility to evaluate the effect of the secondary flow on the stream-wise velocity distribution starting only from the knowledge of the surface velocity and the entropic concept application. The analysis is conducted with the aid of data collected in a large-amplitude meandering laboratory flume for two different values of the width-to-depth ratio. Results show that the location of the maxi…

Lidocaine versus ropivacaine for postoperative continuous paravertebral nerve blocks in patients undergoing laparoscopic bowel surgery: a randomized,…

2015

Daniela Ghisi,1,3 Andrea Fanelli,1,2 Julie Jouguelet-Lacoste,1 Luca La Colla,1,4 Anne-Sophie Auroux,1,5 Jacques E Chelly1 1Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 2Anesthesia and Intensive Care Unit, Policlinico S.Orsola-Malpighi, Bologna, Italy; 3Department of Anesthesia and Postoperative Intensive Care, Istituto Ortopedico Rizzoli, Bologna, Italy; 4Department of Anesthesia, Intensive Care and Pain Therapy, Università degli Studi di Parma, Parma, Italy 5Institut des Sciences Pharmaceutiques et Biologiques-Faculté de Pharmacie de Lyon Université Claude Bernard Lyon, FranceBackground and objectives: Lidocain…

Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial

2020

Funding: Transgène; International audience; Treatment of chronic hepatitis B (CHB) typically requires life-long administration of drugs. Cohort and pre-clinical studies have established the link between a functional T-cell-mounted immunity and resolution of infection. TG1050 is an adenovirus 5-based vaccine that expresses HBV polymerase and domains of core and surface antigen and has shown immunogenicity and antiviral effects in mice. We performed a phase 1 clinical trial to assess safety and explore immunogenicity and early efficacy of TG1050 in CHB patients. This randomized, double blind, placebo-controlled study included two sequential phases: one single dose cohort (SD, n = 12) and one …

Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Hemophilus influenzae type b vaccine; Infanrix™ hexa: T…

2014

Infant vaccination using 2-dose priming at 3 and 5 mo of age with a booster at 11–12 mo of age was pioneered in Italy. The 3-5-11 schedule is now used in a growing number of European countries. Infanrix™ hexa (DTPa-HBV-IPV/Hib, GlaxoSmithKline Vaccines) was first licensed for use in 2000 and has been the only pediatric hexavalent vaccine available since 2005. We reviewed available clinical trial data describing the immunogenicity of DTPa-HBV-IPV/Hib when administered at 3, 5, and 11 mo of age, and conducted an analysis of safety using global and Italian post-marketing surveillance data. In Italy, DTPa-HBV-IPV/Hib has a demonstrated safety record extending over a decade of use, it has been a…

Systematic review and meta-analysis of the efficacy and safety of minocycline in schizophrenia

2017

ObjectiveOur aim was to perform an updated systematic review and meta-analysis on the efficacy and safety of adjunctive minocycline as a treatment of schizophrenia.MethodsWe conducted a PubMed/Scopus database search from inception to 3 February 2016 for randomized, placebo-controlled trials (RCTs), open non-randomized studies, and case reports/series evaluating minocycline in patients with schizophrenia. Random-effects meta-analysis of positive, negative, depressive, and cognitive symptom rating scales, discontinuation and adverse effects rates calculating standardized mean difference (SMD), and risk ratios±95% confidence intervals (CI95%) were calculated.ResultsSix RCTs were eligible (mino…

Uwagi dotyczące schematu cielesnego w "Fenomenologii percepcji" Maurice'a Merleau-Ponty'ego

2013

La meta e il percorso. Sguardi e menti di viaggiatori nella Grecia antica

2022

L’articolo indaga alcuni regimi scopici e ‘menti’ degli antichi viaggiatori greci. Esso prende in considerazione: gli sguardi omerici, vari ma tutti legati tra loro dall’essere rivolti verso specifici punti, singoli o, nel quadro di una conoscenza cumulativa, ‘sommati’ gli uni agli altri; il modo di guardare del sapiente, che riflette sulla relazione tra tutto ciò che vede durante il percorso; quello del turista, che concentra l’osservazione sulla meta scelta – a volte anche soltanto per potere raccontare di esservi stato; quello del lettore, che ‘si sposta’ attraverso i libri di viaggio o di storia; e altri sguardi che costituiscono intrecci o variazioni di quelli precedenti, presentandosi…

Survival, Growth and Mycorrhization of Containerised Pinus sylvestris and Picea abies Seedlings of Different Provenances Outplanted in a Forest Clear…

2017

Abstract We studied field performance of containerised Pinus sylvestris and Picea abies seedlings of different provenances. Shoot height, needle chemical composition, root collar diameter, root mycorrhization and mycorrhizal species composition were evaluated after four growing seasons following outplanting. The results showed that in general spruce had better survival than pine. Ectomycorrhizas on spruce were dominated by Wilcoxina, Amphinema and Tylospora, while on pine — by Suillus and Thelephora species. Spruce and pine showing best growth rates were colonised by ectomycorrhizal fungus Amphinema sp. In conclusion, the results demonstrated that forest nursery practices as well as provena…