Search results for "pine"
showing 10 items of 2022 documents
Critical factors influencing international sporting success of the Philippines : the athletes' perspective
2017
The aim of this study is to contribute to the understanding of the recent declining performance of the Philippines in international sporting competitions by identifying and evaluating relevant factors that are critical to its international success through the perspective of the national elite athletes. An evaluation of the organizational effectiveness of the national sports governing bodies provides explanation to the poor performance of the country in major international competitions such as the Southeast Asian (SEA)Games. One of the most recent approaches used in measuring organizational effectiveness is the Sport Policy factors Leading to International Sporting Success (SPLISS) model. Th…
Love, Relationships and Couple Happiness: A Cross-Cultural Comparison Among Spanish Couples and Moroccan Couples in Southern Spain
2021
Love and relationships are sociocultural constructions that, in recent times, have experienced great changes in terms of type of relationship, type of love and happiness of the couple. Few studies have analysed the love relationships immigrant population in Europe. This study aims to explore the differences and similarities in love styles between Spaniards and Moroccan immigrants, the country’s largest foreign population, and analyse the relationship between these styles and level of couple happiness. This cross-sectional study disseminated a survey to young adults between the ages of 18 and 40 in southern Spain. Of those who received the survey, 574 young adults responded, of which 182 wer…
Being positive, being hopeful, being happy : young adults reflecting on their future in times of austerity
2020
The aim of this article is to analyse the ways in which young adults reflect on their futures. We are particularly interested in how they expect to organize their lives in conditions that seem to offer pessimistic rather than hopeful prospects. How does this happen under social conditions where the major public and individual concerns are with how young adults organize their material lives and how they earn sufficient livelihoods to become good citizens? What are the grounds for their future visions? In our analysis we use 40 interviews with young Finnish adults aged between 18 and 30. The respondents are students, as well as employed and unemployed young adults. Our findings show that the…
Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants
2012
Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J. excelsa, monoterpenes were the most abundant compounds. In J. oxycedrus, cis-calamenene (7.8 %), cuparene (3.8 %), and cis-thujopsenal (2.0 %) have been detected for the first time. The cytotoxic activity of these essential oils against drug-sensitive CCRF-CEM and multidrug-resistant P-glycoprotein-expressing CEM/ADR5000 leukemia cells has been investigated (IC₅₀ values: 29.46…
[Pharmacogenomics of antiretrovirals].
2008
HIV infection is a serious but treatable disease, yet current treatment is limited by development of resistance and high rates of adverse drug reactions. Antiretroviral therapy is especially suitable for pharmacogenomic investigation as both drug exposure and treatment response can be reliably measured. Increasing knowledge about genes implicated in pharmacokinetics, mode of action, efficacy, and toxicity of drugs has already provided relevant results for clinical practice, for example: The strong association of the abacavir hypersensitivity reaction with HLA-B*5701 permits testing patients for the allele, and if present avoiding the drug and therefore preventing the reaction. Persons with …
Efavirenz induces interactions between leucocytes and endothelium through the activation of Mac-1 and gp150,95
2013
The potential cardiovascular (CV) toxicity associated with combined antiretroviral therapy (cART) has been attributed mainly to the nucleoside reverse transcriptase inhibitors abacavir and didanosine. However, the other two components of cART--non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs)--may also be implicated, either directly or by influencing the action of the other drugs. This study evaluates the acute direct effects of the NNRTIs efavirenz and nevirapine and one of the most widely employed PIs, lopinavir, on leucocyte-endothelium interactions, a hallmark of CV disease.Drugs were analysed in vitro in human cells (interactions of peripheral blood…
Wood-inhabiting fungal responses to forest naturalness vary among morpho-groups
2021
The general negative impact of forestry on wood-inhabiting fungal diversity is well recognized, yet the effect of forest naturalness is poorly disentangled among different fungal groups inhabiting dead wood of different tree species. We studied the relationship between forest naturalness, log characteristics and diversity of different fungal morpho-groups inhabiting large decaying logs of similar quality in spruce dominated boreal forests. We sampled all non-lichenized fruitbodies from birch, spruce, pine and aspen in 12 semi-natural forest sites of varying level of naturalness. The overall fungal community composition was mostly determined by host tree species. However, when assessing the …
Genomic instability induced by α-pinene in Chinese hamster cell line.
2012
Here, we report the effects of exposure of mammalian cells to α-pinene, a bicyclic monoterpene used in insecticides, solvents and perfumes. Morphological analysis, performed in V79-Cl3 cells exposed for 1 h to increasing concentrations (25 up to 50 μM) of α-pinene, indicated a statistically significant increase in micronucleated and multinucleated cell frequencies; apoptotic cells were seen at 40 and 50 μM. This monoterpene caused genomic instability by interfering with mitotic process; in fact, 50% of cells (versus 19% of control cells) showed irregular mitosis with multipolar or incorrectly localised spindles. Cytogenetic analysis demonstrated high-frequency hypodiploid metaphases as well…
An AFLP clock for the absolute dating of shallow-time evolutionary history based on the intraspecific divergence of southwestern European alpine plan…
2009
The dating of recent events in the history of organisms needs divergence rates based on molecular fingerprint markers. Here, we used amplified fragment length polymorphisms (AFLPs) of three distantly related alpine plant species co-occurring in the Spanish Sierra Nevada, the Pyrenees and the southwestern Alps/Massif Central to establish divergence rates. Within each of these species (Gentiana alpina, Kernera saxatilis and Silene rupestris), we found that the degree of AFLP divergence (D(N72)) between mountain phylogroups was significantly correlated with their time of divergence (as inferred from palaeoclimatic/palynological data), indicating constant AFLP divergence rates. As these rates d…
Tourism in the European economic crisis: Mediatised worldmaking and new tourist imaginaries in Greece
2016
The article interrogates the rationale and origins of changing imaginaries of tourism in Greece in the context of the current economic crisis. We detect a radical change in the ‘picture’ of the country that circulates in global media conduits (YouTube, Facebook, official press websites and personal blogs). We enact a journey into past media representations of Greece as an idyllic peasant and working-class site, but proceed to highlight that such representations are being recycled today by Greeks (especially but not exclusively) living and studying abroad. This stereotype, which focuses on embodied understandings of happiness and well-being, is being challenged by the current economic crisi…