Search results for "plant extracts"

showing 10 items of 510 documents

A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.

2003

Six acetophenones (1-6) and one gamma-pyrone (7), previously isolated from Helichrysum italicum, were tested for their ability to inhibit enzymatic and non-enzymatic lipid peroxidation, the stable 1,1-diphenyl-2-pycryl-hydrazyl free radical, superoxide scavenging and arachidonic acid metabolism. In addition, they were studied in different experimental models such as the chronic inflammation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA), the phospholipase A(2)-induced mouse paw oedema test, the carrageenan-induced mouse paw oedema test, and the writhing induced by acetic acid in the mouse. Of the assayed compounds, only 1 inhibited enzymatic lipid peroxidation but had no effect on no…

AntioxidantFree RadicalsNeutrophilsmedicine.medical_treatmentCarrageenanHelichrysum italicumLeukotriene B4Phospholipases ALipid peroxidationchemistry.chemical_compoundMiceIndometacinGlucosidesmedicineAnimalsEdemaRats WistarPeroxidasePharmacologyHelichrysumInflammationPhospholipase AAnalgesicsArachidonic AcidbiologyDose-Response Relationship DrugSuperoxidePlant ExtractsAcetophenonesEarbiology.organism_classificationCarrageenanHindlimbRatsBiochemistrychemistryTetradecanoylphorbol AcetateArachidonic acidFemaleLipid Peroxidationmedicine.drugEuropean journal of pharmacology
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Bioactive components of caper (Capperis spinosa L.) from Sicily and antioxidant effects in a red meat simulated gastric digestion

2007

An increasing body of evidence on the association between adherence to the Mediterranean diet and healthy status is being accumulated. Floral buds of Capparis spinosa L. are commonly used in the Mediterranean cuisine as flavoring for meat and other foods. The present study evaluated bioactive components and antioxidant activity of Sicilian capers stabilized in salt. Whereas alpha-tocopherol was absent, low levels of gamma-tocopherol and vitamin C were measured. With reference to one serving size (8.6 g of capers), rutin was 13.76 mg, isothiocyanates, recently acknowledged as anticarcinogen phytochemicals, were 42.14 micromol, total phenols were 4.19 mg of gallic acid equivalents (GAE), and …

AntioxidantHot TemperatureMeatmedicine.medical_treatmentModels BiologicalThiobarbituric Acid Reactive SubstancesAntioxidantschemistry.chemical_compoundRutinfoodLipid oxidationmedicineAnimalsFood scienceGallic acidSicilyABTSGastric JuiceVitamin CPlant ExtractsCapparis spinosaGeneral Chemistryfood.foodCapparisOxidative StresschemistryBiochemistryDigestionTroloxLipid PeroxidationGeneral Agricultural and Biological Sciences
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Antioxidant activities of sicilian prickly pear (Opuntia ficus indica) fruit extracts and reducing properties of its betalains: betanin and indicaxan…

2002

Sicilian cultivars of prickly pear (Opuntia ficus indica) produce yellow, red, and white fruits, due to the combination of two betalain pigments, the purple-red betanin and the yellow-orange indicaxanthin. The betalain distribution in the three cultivars and the antioxidant activities of methanolic extracts from edible pulp were investigated. In addition, the reducing capacity of purified betanin and indicaxanthin was measured. According to a spectrophotometric analysis, the yellow cultivar exhibited the highest amount of betalains, followed by the red and white ones. Indicaxanthin accounted for about 99% of betalains in the white fruit, while the ratio of betanin to indicaxanthin varied fr…

AntioxidantIndolesPolymersPyridinesmedicine.medical_treatmentAscorbic AcidAntioxidant activities of sicilian prickly pearAntioxidantschemistry.chemical_compoundLipid oxidationPhenolsBetalainBotanymedicineLipoprotein oxidationFood scienceEdetic AcidBetaninFlavonoidsPlant Extractsfood and beveragesOpuntiaPolyphenolsGeneral ChemistryPigments BiologicalBetaxanthinschemistryPolyphenolSpectrophotometryFruitTroloxBetacyaninsGeneral Agricultural and Biological SciencesIndicaxanthinOxidation-ReductionCopperJournal of agricultural and food chemistry
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Polyphenol Characterization, Antioxidant and Skin Whitening Properties of Alnus cordata Stem Bark

2019

In this study, we investigated the phenolic composition of the crude extract (MeOH 80 %) of Alnus cordata (Loisel.) Duby stem bark (ACE) and its antioxidant and skin whitening properties. RP-LC-DAD analysis showed a high content of hydroxycinnamic acids (47.64 %), flavanones (26.74 %) and diarylheptanoids (17.69 %). Furthermore, ACE exhibited a dose-dependent antioxidant and free-radical scavenging activity, expressed as half-maximal inhibitory concentration (IC50 ): Oxygen radical absorbance capacity (ORAC, IC50 1.78 μg mL-1 )>Trolox equivalent antioxidant capacity (TEAC, IC50 3.47 μg mL-1 )>2,2-Diphenyl-1-picrylhydrazyl (DPPH, IC50 5.83 μg mL-1 )>β-carotene bleaching (IC50 11.58 μg mL-1 )…

AntioxidantOxygen radical absorbance capacityDPPHmedicine.medical_treatmentTrolox equivalent antioxidant capacityBioengineeringAlnus cordata; antimelanogenic activity; Betulaceae; mushroom tyrosinase; polyphenols; RP-LC-DAD analysis; zebrafish; Alnus; Animals; Antioxidants; Biphenyl Compounds; Enzyme Inhibitors; Monophenol Monooxygenase; Picrates; Plant Bark; Plant Extracts; Polyphenols; Skin; ZebrafishAlnus01 natural sciencesBiochemistryAntioxidantschemistry.chemical_compoundPicratesmedicineAnimalsFood scienceEnzyme InhibitorsMolecular BiologyIC50ZebrafishSkinbiologyMonophenol MonooxygenasePlant Extracts010405 organic chemistryBiphenyl CompoundsPolyphenolsSkin whiteningGeneral ChemistryGeneral Medicinebiology.organism_classificationAlnus cordata0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryPolyphenolPlant BarkMolecular Medicine
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Antioxidant and anti-inflammatory properties of plants extract

2019

Inflammation is an adaptive response triggered by noxious stimuli and conditions such as infection and tissue injury [...]

AntioxidantPhysiologymedicine.drug_classbusiness.industrymedicine.medical_treatmentClinical BiochemistryInflammationCell BiologyPharmacologyBiochemistryAnti-inflammatoryEditorialAntioxidant Antiinflammatory plant extractsNoxious stimulusmedicinemedicine.symptombusinessMolecular Biologypsychological phenomena and processes
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Delivery of liquorice extract by liposomes and hyalurosomes to protect the skin against oxidative stress injuries.

2015

Liquorice extract, obtained by percolation in ethanol of Glycyrrhiza glabra L. roots, was incorporated in liposomes and hyalurosomes, new phospholipid-sodium hyaluronate vesicles, and their protective effect against oxidative stress skin damages was probed. As a comparison, raw glycyrrhizin was also tested. All the vesicles were small in size (≤ 100 nm), with a highly negative zeta potential ensuring long-term stability, and able to incorporate a high amount of the extract. In vitro tests showed that the liquorice extract loaded in vesicles was able to scavenge DPPH free radical (80% inhibition) and to protect 3T3 fibroblasts against H2O2-induced oxidative stress, restoring the normal condi…

AntioxidantPolymers and PlasticsDPPHmedicine.medical_treatmentAdministration TopicalChemistry PharmaceuticalPharmacologymedicine.disease_causePlant Rootschemistry.chemical_compoundMiceDrug StabilityIn vivoCell MovementMaterials TestingMaterials ChemistrymedicineGlycyrrhizaAnimalsEdemaHyaluronic AcidGlycyrrhizinCell ProliferationSkinLiposomeDrug CarriersbiologyPlant ExtractsOrganic Chemistry3T3 CellsFree Radical Scavengersbiology.organism_classificationOxidative StresschemistryBiochemistryLiposomesGlycyrrhizaFemaleDrug carrierOxidative stressCarbohydrate polymers
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Coffee components and cardiovascular risk: beneficial and detrimental effects

2014

Coffee consists of several biological active compounds, such as caffeine, diterpenes, chlorogenic acids, and melanoidins, which may affect human health. The intake of each compound depends on the variety of coffee species, roasting degree, type of brewing method and serving size. The bioavailability and the distribution of each compound and its metabolites also contribute to coffee mechanisms of action. The health benefits of coffee consumption regarding cardiovascular system and metabolism mostly depend on its antioxidant compounds. In contrast, diterpenes and caffeine may produce harmful effects by raising lipid fraction and affecting endothelial function, respectively. Studying the mecha…

AntioxidantSettore MED/09 - Medicina InternaPolymersmedicine.medical_treatmentLipid fractionCoffee consumptionBiologyHealth benefitsCardiovascular SystemCoffeeHuman healthchemistry.chemical_compoundAlkaloidsCaffeinemedicineHumansFood scienceSettore MED/49 - Scienze Tecniche Dietetiche ApplicatePlant ExtractsPolyphenolscoffee cardiovascular riskDiabetes Mellitus Type 2chemistryCardiovascular DiseasesChlorogenic AcidDiterpenesCaffeineFood Science
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Ultrasonically-Assisted and Conventional Extraction from Erodium Glaucophyllum Roots Using Ethanol:Water Mixtures: Phenolic Characterization, Antioxi…

2020

The paper presents experimental results concerning the ultrasonically-assisted extraction of bioactive compounds from Erodium glaucophyllum roots. A comparison with conventional methodology is presented, and thereby the phytochemical composition and the antioxidant and anti-inflammatory activities of extracts are evaluated. The phenolic profile of Erodium extracts was analyzed by TOF&ndash

Antioxidantantioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsPharmaceutical Science02 engineering and technologyPlant RootsAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoverySolid phase extractionCarotenoidChromatography High Pressure Liquidanti-inflammatorychemistry.chemical_classificationbiologyChemistryultrasound04 agricultural and veterinary sciences021001 nanoscience & nanotechnology040401 food scienceUltrasonic WavesChemistry (miscellaneous)Molecular MedicineAntioxidant0210 nano-technologysolid-liquid extractionErodiumPolyphenolTECNOLOGIA DE ALIMENTOSmedicine.drug_classAnti-inflammatoryArticlelcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryPhenolsUltrasoundmedicinePhysical and Theoretical ChemistryChromatographyEthanolPlant ExtractsOrganic ChemistryExtraction (chemistry)Solid-liquid extractionbiology.organism_classificationpolyphenolTracheophytaPolyphenolSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationTroloxAnti-inflammatoryChromatography LiquidMolecules
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UV-Induced Changes of Active Components and Antioxidant Activity in Postharvest Pigeon Pea [Cajanus cajan (L.) Millsp.] Leaves

2013

In this study, the effect of UV irradiation (UV-A, UV-B, and UV-C) on phytochemicals, total phenolics, and antioxidant activity of postharvest pigeon pea leaves was evaluated. The response of pigeon pea leaves to UV irradiation was phytochemical specific. UV-B and UV-C induced higher levels of phytochemicals, total phenolics, and antioxidant activity in pigeon pea leaves compared with UV-A. Furthermore, UV-B irradiation proved to possess a long-lasting effect on the levels of phenolics and antioxidant activity. After adapting for 48 h at 4 °C following 4 h UV-B irradiation, total phenolics and antioxidant activity were approximately 1.5-fold and 2.2-fold increased from 39.4 mg GAE/g DM and …

AntioxidantbiologyPlant ExtractsChemistrymedicine.medical_treatmentActive componentsfood and beveragesGeneral Chemistrybiology.organism_classificationAntioxidantsPlant LeavesCajanusCajanusPhenolsPhytochemicalBotanymedicinePostharvestFood scienceGeneral Agricultural and Biological SciencesJournal of Agricultural and Food Chemistry
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Anti-inflammatory activity of erycristagallin, a pterocarpene from Erythrina mildbraedii.

2003

Erycristagallin, a pterocarpene isolated from Erythrina mildbraedii, was tested in vitro for its antioxidant properties on the stable 2,2-diphenyl-1-pycryl-hydrazyl (DPPH) free radical and on the arachidonic acid metabolism. In addition, erycristagallin was tested on different experimental models of inflammation, such as the acute and chronic inflammation induced by the application of 12-O-tetradecanoylphorbol 13-acetate (TPA) on mice and the phospholipase A(2)-induced mouse paw oedema test. In the carrageenan-induced mouse paw oedema test, the ethyl acetate extract obtained from E. mildbraedii showed anti-inflammatory activity, and erycristagallin was isolated as the active principle. In v…

Antioxidantmedicine.drug_classDPPHmedicine.medical_treatmentAnti-Inflammatory AgentsInflammationPharmacologyCarrageenanHeterocyclic Compounds 4 or More RingsLeukotriene B4Anti-inflammatoryAntioxidantsPhospholipases Achemistry.chemical_compoundMicePicratesIn vivomedicineAnimalsEdemaRats WistarErythrinaPharmacologyPhospholipase AArachidonic AcidPlant ExtractsBiphenyl CompoundsEarFree Radical ScavengersIsoflavonesIn vitroHindlimbRatsBiphenyl compoundchemistryBiochemistryFemalemedicine.symptomEuropean journal of pharmacology
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