Search results for "platinum"

showing 10 items of 629 documents

Development of trackable metal-based drugs: new generation of therapeutic agents

2016

International audience; In medicinal chemistry, the aim is not only to conceive ever more efficient molecules, but also to understand their mechanism of action. In very recent years, a new promising strategy was developed to tackle this issue: the conception of trackable therapeutic agents. Metal-based drugs are ideal to exploit this expanding area of research.

Diagnostic ImagingExploitTheranostic NanomedicineComputer scienceNanotechnologyphosphine-porphyrinpotential anticancer agents[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistry01 natural sciencesin-vivo[ CHIM ] Chemical SciencesTheranostic NanomedicineInorganic Chemistrytheranostic agentsplatinum(ii) complexesorganometallic compoundsAnimals[CHIM]Chemical Sciences010405 organic chemistry[ CHIM.INOR ] Chemical Sciences/Inorganic chemistry0104 chemical sciences3. Good healthcancer-cellsRisk analysis (engineering)photodynamic therapycytotoxic propertiesDrug Designheterocyclic carbene complexes
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In situ characterization of the high pressure – high temperature melting curve of platinum

2019

AbstractIn this work, the melting line of platinum has been characterized both experimentally, using synchrotron X-ray diffraction in laser-heated diamond-anvil cells, and theoretically, using ab initio simulations. In the investigated pressure and temperature range (pressure between 10 GPa and 110 GPa and temperature between 300 K and 4800 K), only the face-centered cubic phase of platinum has been observed. The melting points obtained with the two techniques are in good agreement. Furthermore, the obtained results agree and considerably extend the melting line previously obtained in large-volume devices and in one laser-heated diamond-anvil cells experiment, in which the speckle method wa…

DiffractionMaterials scienceAb initioAnalytical chemistrylcsh:Medicinechemistry.chemical_element02 engineering and technology01 natural sciencesMelting curve analysisArticlelaw.inventionlawPhase (matter)0103 physical scienceslcsh:Science010306 general physicsMultidisciplinarylcsh:RAtmospheric temperature range021001 nanoscience & nanotechnologySynchrotronMaterials sciencePhase transitions and critical phenomenachemistryMelting pointlcsh:Q0210 nano-technologyPlatinumScientific Reports
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Isomerism in [MCl2(ERR‘)2] (M = Pd, Pt; E = S, Se; R, R‘ = Me, Ph)

2006

A series of thioether and selenoether complexes [MCl2(EPh2)2] and [MCl2(SMePh)2] (M = Pt, Pd; E = S, Se) have been prepared and characterized to explore the isomerism of the complexes in solution and in the solid state. The NMR spectroscopic information indicates that only one isomer is present in solution in case of the palladium complexes, while two isomers are formed in the case of most platinum complexes. Single-crystal X-ray structures of trans-[PdCl2(SPh2)2] (1t), trans-[PdCl2(SePh2)2] (2t), cis-[PtCl2(SePh2)2] (4c), trans-[PdCl2(SMePh)2] (5t), and trans-[PtCl2(SMePh)2] (7t) are reported and have been used as starting points for the X-ray powder diffraction structure determinations us…

DiffractionRietveld refinementSolid-statechemistry.chemical_elementGeneral ChemistryCondensed Matter Physicschemistry.chemical_compoundCrystallographyThioetherchemistrySolid phasesGeneral Materials SciencePlatinumPowder diffractionPalladiumCrystal Growth & Design
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Reactions of pyridine-2-carbaldimines with chloro-bridged palladium(II) and platinum(II) 2-methylallyl dimers. Solution behaviour of the cationic com…

1987

Abstract The reactions of pyridine-2-carbaldimines, py-2- CHNR (R = C6H4OMe-p, Me), with allylic dimers [MCl(n3-2-MeC3H4)]2 give rise to stoichiometry, concentration, solvent and temperature dependent equilibria, in which the cationic complexes [M(n3- 2-MeC3H4)(py-2-CHNR)]+ and the anion [MCl2(n3- 2-MeC3H4)]- or Cl- are involved. In general, the ligand/dimer reaction (1/1 molar ratio) yields the ionic products [M(n3-2-MeC3H4)(py-2-CHNR)]- [MCl2(n3-2-MeC3H4)], which can be isolated as solids, whereas the same reaction in a 1/0.5 molar ratio yields the species [M(n3-2-MeC3H4 )(py-2-CH NR)] Cl, which can be studied only in solution, but are easily converted into [M(n3-2-MeC3H4)(py-2-CH NR…

DimerInorganic chemistryCationic polymerizationchemistry.chemical_elementMetallacycleMedicinal chemistryInorganic ChemistrySolventchemistry.chemical_compoundchemistryPyridineMaterials ChemistryPhysical and Theoretical ChemistryPlatinumAcetonitrilePalladiumInorganica Chimica Acta
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Electrochemical detection of dopamine with negligible interference from ascorbic and uric acid by means of reduced graphene oxide and metals-NPs base…

2021

Abstract Dopamine is an important neurotransmitter involved in many human biological processes as well as in different neurodegenerative diseases. Monitoring the concentration of dopamine in biological fluids, i.e., blood and urine is an effective way of accelerating the early diagnosis of these types of diseases. Electrochemical sensors are an ideal choice for real-time screening of dopamine as they can achieve fast, portable inexpensive and accurate measurements. In this work, we present electrochemical dopamine sensors based on reduced graphene oxide coupled with Au or Pt nanoparticles. Sensors were developed by co-electrodeposition onto a flexible substrate, and a systematic investigati…

Dopaminechemistry.chemical_elementMetal NanoparticlesNanotechnologyAscorbic AcidPlatinum nanoparticlesBiochemistryAnalytical Chemistrylaw.inventionlawSettore ING-IND/17 - Impianti Industriali MeccaniciEnvironmental ChemistryHumansElectrodesSpectroscopyPlatinumDetection limitChemistryGrapheneSubstrate (chemistry)Electrochemical TechniquesUric AcidSettore ING-IND/23 - Chimica Fisica ApplicataLinear rangeColloidal goldElectrodeGraphiteGoldDopamine Electrochemical sensor Graphene oxide Metal nanoparticles Neurodegenerative disease UrinePlatinumAnalytica chimica acta
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Preliminary results on the electrostatic double-layer force between two surfaces with high surface potentials

1998

Abstract The aim of this study is to measure interaction forces between surfaces with high electric potentials in aqueous electrolyte solutions. Therefore the force between a gold sample and a gold sphere attached to the end of an atomic force microscope cantilever was measured. Gold sample and sphere were electrically connected and served as the working electrode. A potential was applied via a platinized platinum electrode. Experimental results are compared to forces approximated with the Poisson-Boltzmann theory.

Double layer (biology)CantileverWorking electrodePhysics::Instrumentation and DetectorsAtomic force microscopyElectrostatic force microscopeSurface forceAnalytical chemistrychemistry.chemical_elementMolecular physicsColloid and Surface ChemistrychemistryElectrodePlatinumColloids and Surfaces A: Physicochemical and Engineering Aspects
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CO2 turned into a nitrogen doped carbon catalyst for fuel cells and metal–air battery applications

2021

Heteroatom doped metal-free catalysts are one of the most promising replacements for platinum for the alkaline oxygen reduction reaction (ORR). Due to the lack of metal atoms, they are extremely stable and environmentally friendly. However, production of carbon nanomaterials can have a very high CO2 footprint. In this study, we present ORR catalysts made directly from CO2via molten salt CO2 electrolysis. The deposited carbon powder is doped with nitrogen using pyrolysis in the presence of dicyandiamide. The effect of molten carbonate electrolyte composition towards the final ORR activity in 0.1 M KOH is studied. A thorough physico-chemical study of the starting carbons and N-doped catalysts…

ElectrolysisMaterials scienceHeteroatomchemistry.chemical_elementPollutionCatalysislaw.inventionchemistryChemical engineeringlawEnvironmental ChemistryRotating disk electrodeMolten saltPlatinumCarbonBET theoryGreen Chemistry
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Electrochemistry as an Attractive and Effective Tool for the Synthesis and Immobilization of Porphyrins on an Electrode Surface

2014

Magnesium(II) 10-phenyl-5,15-p-ditolylporphyrin is easily and cleanly transformed by electrolysis. A nitro group is first introduced at the free meso position by anodic substitution. Hydrogenation into the amine is then carried out electrocatalytically under ambient conditions with water as a hydrogen supplier. The synthesized porphyrin under the nickel(II) form can be covalently grafted onto a platinum electrode by electrochemical reduction of the diazonium cation, generated in situ by a reaction of the nickel(II) aminoporphyrin with sodium nitrite and trifluoroacetic acid. The electrosynthesized thin film gives an electrochemical response typical of a porphyrin material. Films grown under…

ElectrolysisPorphyrinsMagnesiumOrganic ChemistryInorganic chemistrychemistry.chemical_elementElectrochemical TechniquesGeneral ChemistryElectrochemistryElectrosynthesisPorphyrinElectrolysisCatalysislaw.inventionchemistry.chemical_compoundNickelchemistryNickellawElectrodePlatinumElectrodesOxidation-ReductionPlatinumChemistry - A European Journal
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Electrolyses model development for metal/electrolyte interface: Testing with microrespiration sensors

2011

Abstract Initial process of electrolysis is investigated using platinum and tungsten wires as hydrogen electrodes and inductive kickback voltage peak based power unit. Microelectrodes are used to determine concentrations of dissolved hydrogen and pH close to wire electrodes. It is observed that concentration of dissolved hydrogen increases faster on tungsten electrode as on platinum. Authors explain this fact with differences of hydrogen evolution reaction on both materials – inductive kickback voltage peak power unit is supplying very short voltage pulses with limited energy what is enough only for hydrogen adsorption on platinum electrode, but is sufficient for full hydrogen evolution rea…

ElectrolysisStandard hydrogen electrodeHydrogenRenewable Energy Sustainability and the EnvironmentChemistryInorganic chemistryAnalytical chemistryEnergy Engineering and Power Technologychemistry.chemical_elementElectrolyteTungstenCondensed Matter Physicslaw.inventionFuel TechnologylawPalladium-hydrogen electrodeReversible hydrogen electrodePlatinumInternational Journal of Hydrogen Energy
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Ferric sludge derived from the process of water purification as an efficient catalyst and/or support for the removal of volatile organic compounds

2019

Ferric chloride solutions are used as coagulants or flocculants in water treatment operations for human consumption. This treatment produces large amounts of clay-type solids formed mainly of montmorillonite with iron oxides and humic substances. This ferric sludge can be used as an efficient catalyst for the removal of volatile organic compounds (VOCs) by total oxidation. This waste isolated in the purification process has been activated by calcinations in air, characterized by several physicochemical techniques and employed as a catalyst for the removal by total oxidation of representative VOCs: toluene, propane and mixtures of toluene/propane with or without water. This ferric sludge has…

Environmental EngineeringMaterials scienceHealth Toxicology and Mutagenesis0208 environmental biotechnologychemistry.chemical_elementPortable water purification02 engineering and technology010501 environmental sciencesFerric CompoundsSludge01 natural sciencesCatalysisWater PurificationmedicineEnvironmental ChemistryEfficient catalystValenciaPlatinum0105 earth and related environmental sciencesVolatile Organic CompoundsSewagebiologyWaste managementPublic Health Environmental and Occupational HealthVOCsGeneral MedicineGeneral Chemistrybiology.organism_classificationPollutionPurification of water020801 environmental engineeringchemistryScientific methodFerricSupportPlatinumOxidation-Reductionmedicine.drugChemosphere
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