Search results for "pond"
showing 10 items of 742 documents
Letters to the Editor : Stratégies d’utilisation par une communauté de chercheurs francophones et tentative de caractérisation du genre
2002
Cet article se fixe comme objectif d’analyser la fonction et l’utilisation du genre Letters to the Editor au sein d’une communauté de chercheurs francophones. L’impact et la représentation de ce mode d’expression scientifique ont été mesurés à l’aide d’une enquête sous forme de questionnaire dont les résultats sont rapportés et analysés. Cette étude permet de dégager les stratégies d’utilisation du genre et conduit à proposer quelques pistes pouvant aboutir à la caractérisation du genre. Ce travail s’appuie également sur l’analyse comparée d’un corpus (1999-2001) composé à partir d’une revue de biologie et d’une revue médicale. The aim of this paper is to analyse the goal, role and use of t…
Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis
2000
The objective of this study was to investigate TNF promoter region polymorphisms for association with susceptibility to ankylosing spondylitis (AS). The TNF -238 and -308 polymorphisms were genotyped in 306 English AS cases and 204 ethnically matched healthy B27-positive controls, and 96 southern German AS cases, 58 B27-positive and 251 B27-negative ethnically matched controls. Additionally, the TNF -376 polymorphism was genotyped in the southern German cases and controls. In the southern German AS patients a significant reduction in TNF -308.2 alleles was seen, compared with B27 positive controls (odds ratio 0.4, P = 0.03, 95% confidence interval 0.2-0.9), but no difference in allele frequ…
Alexander Chak’s Correspondence – historical and artistic value of the Latvian cultural heritage
2013
Evaluating and grouping the literature historical relics, including the correspondences by letters between famous people, for a ground (base) we could take categories which demonstrate the qualities which have elements from the material world in an anent with a human. The cultural historian Fridrich Waidacher by researching the interconnection and selective values between material and spiritual world classified the evidences of material world in several chapters which are not strictly caged in permanent schemes (patterns). The division was made by taking F. Waidacher conception as a base and researching the correspondence by letters of Latvian poets and cultural workers: The potential value…
Rumination for innovation? : analyzing the longitudinal effects of work-related rumination on creativity at work and off-job recovery
2017
ABSTRACTWork-related rumination is not a single construct, but consists of a dimension associated with negative emotions or affect (affective rumination), and a dimension associated with reflective thinking and applying strategies to solve problems (problem-solving pondering). In this three-wave longitudinal study across two years (N = 630) we investigated whether the relationships between work-related rumination, off-job recovery, and creativity at work varied along the two dimensions of work-related rumination. In addition, we tested whether the relationships followed normal, reversed, or reciprocal causation. The results showed, first, that in a one-year perspective affective rumination,…
Gli studi machiavelliani di Alphonse Dantier ne "Le Correspondant"
2011
From September 1871 to July 1873 Alphonse Dantier (1810-1882) published, for the prestigious magazine of liberal Catholic inspiration, Le Correspondant, some contributions on the history of Florence, The Medicis and Machiavelli, collected in 1874 in the second volume of his work L’Italie: études historiques for which he was awarded the prize of the Académie Française Marcelin Guérin. Dantier, although anchored to the simplified cliché of Machiavelli “negative genius”, perceived the historiographical talent of the author of Historie fiorentine and contributed to introduce the French Catholic reader to the commitment of the Republican Machiavelli in the sixteenth-century, documenting it throu…
Field and Numerical Tests of the Two-Ponding Depth Procedure for Analysis of Single-Ring Pressure Infiltrometer Data
2013
Abstract The two-ponding depth (TPD) analysis procedure of single-ring infiltrometer data can yield invalid results, i.e., negative values of the field-saturated soil hydraulic conductivity or the matric flux potential, denoting failure of the two-level run. The objective of this study was to test the performance of the TPD procedure in analyzing the single-ring infiltrometer data of different types of soils. A field investigation carried out in western Sicily, Italy, yielded higher failure rates (40%) in two clay loam soils than in a sandy loam soil (25%). A similar result, i.e., fine-textured soils yielding higher failure rates than the coarse-textured one, was obtained using numerically …
Interleukin-17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin-25-Driven In…
2020
Objective To characterize the ecological effects of biologic therapies on the gut bacterial and fungal microbiome in psoriatic arthritis (PsA)/spondyloarthritis (SpA) patients. Methods Fecal samples from PsA/SpA patients pre- and posttreatment with tumor necrosis factor inhibitors (TNFi; n = 15) or an anti-interleukin-17A monoclonal antibody inhibitor (IL-17i; n = 14) underwent sequencing (16S ribosomal RNA, internal transcribed spacer and shotgun metagenomics) and computational microbiome analysis. Fecal levels of fatty acid metabolites and cytokines/proteins implicated in PsA/SpA pathogenesis or intestinal inflammation were correlated with sequence data. Additionally, ileal biopsies obtai…
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
2018
ObjectivePrimary sclerosing cholangitis (PSC) is a genetically complex, inflammatory bile duct disease of largely unknown aetiology often leading to liver transplantation or death. Little is known about the genetic contribution to the severity and progression of PSC. The aim of this study is to identify genetic variants associated with PSC disease progression and development of complications.DesignWe collected standardised PSC subphenotypes in a large cohort of 3402 patients with PSC. After quality control, we combined 130 422 single nucleotide polymorphisms of all patients—obtained using the Illumina immunochip—with their disease subphenotypes. Using logistic regression and Cox proportiona…
Diagnostic strategy in segmentation defect of the vertebrae: a retrospective study of 73 patients
2018
BackgroundSegmentation defects of the vertebrae (SDV) are non-specific features found in various syndromes. The molecular bases of SDV are not fully elucidated due to the wide range of phenotypes and classification issues. The genes involved are in the Notch signalling pathway, which is a key system in somitogenesis. Here we report on mutations identified in a diagnosis cohort of SDV. We focused on spondylocostal dysostosis (SCD) and the phenotype of these patients in order to establish a diagnostic strategy when confronted with SDV.Patients and methodsWe used DNA samples from a cohort of 73 patients and performed targeted sequencing of the five known SCD-causing genes (DLL3,MESP2,LFNG,HES7…
Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients
2020
microRNAs (miRNAs) are small RNAs that regulate different biological processes. Our objective was to identify miRNAs dysregulated in plasma and tissue of patients with abdominal aortic aneurysm (AAA) and explore new potential targets involved in AAA. Fifty-seven subjects were recruited for a plasma study (30 AAA patients, 16 healthy volunteers and 11 patients with atherosclerosis). The expression level of 179 miRNAs was screened in plasma from a subset of samples, and dysregulated miRNAs were validated in the entire study population. Dysregulated miRNAs were also quantified in aortic tissue of 21 AAA patients and 8 organ donors. Applying a gene set enrichment analysis, an interaction map of…