Search results for "poor"

Nutritional parameters associated with prognosis in non-critically ill hospitalized covid-19 patients: the nutri-covid19 study

2021

Background & aims: To investigate the association between the parameters used in nutritional screening assessment (body mass index [BMI], unintentional weight loss [WL] and reduced food intake) and clinical outcomes in non-critically ill, hospitalized coronavirus disease 2019 (COVID-19) patients. Methods: This was a prospective multicenter real-life study carried out during the first pandemic wave in 11 Italian Hospitals. In total, 1391 patients were included. The primary end-point was a composite of in-hospital mortality or admission to ICU, whichever came first. The key secondary end-point was in-hospital mortality. Results: Multivariable models were based on 1183 patients with comple…

Defining poor prognosis markers of implantation for embryo selection by time-lapse

2012

Effect of estrogen in malignant melanoma

2021

Background Melanoma is associated with poor prognosis in its advanced stages. Potential influence of estrogen and its metabolites on melanoma growth has been suggested. Aims The objective of this review was to provide an overview on the evidence related to estrogen in malignant melanoma. Materials and methods Literature search using PubMed, Google Scholar and relevant cross-references of the retrieved articles was performed to review relevant published articles related to estrogen and its effects in malignant melanoma. Results Effect of estrogen signaling on a tissue largely depends on the relative expression of estrogen receptors (ER) α and β. Gender differences in melanoma may be explaine…

Extranodal extension of lymph node metastasis is a marker of poor prognosis in oesophageal cancer: A systematic review with meta-analysis

2016

The extranodal extension (ENE) of nodal metastasis is the extension of neoplastic cells through the nodal capsule into the perinodal adipose tissue. This histological feature has recently been indicated as an important prognostic factor in different types of malignancies; in this manuscript, we aim at defining its role in the prognosis of oesophageal cancer with the tool of meta-analysis. Two independent authors searched SCOPUS and PubMed until 31 August 2015 without language restrictions. The studies with available data about prognostic parameters in subjects with oesophageal cancer, comparing patients with the presence of ENE (ENE+) versus only intranodal extension (ENE-), were considered…

Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

2021

Acute coronary syndrome is a factor for poor prognosis and recurrent cardiovascular events. Adequate antiplatelet therapy is crucial in patients with the acute coronary syndrome for risk reduction. Such treatment is well described in four documents issued by the European Society of Cardiology, which precisely illustrate the use of antiplatelets in the settings of ST-elevated and non-ST elevated myocardial infarction. Despite its unquestioned role in the treatment of acute coronary syndrome, recent real-world-data from Polish registries reveal poor adherence to the guidelines-recommended antiplatelet treatment in Poland. Thus, we present here a comprehensive review of the use of antiplatelet…

Primary intraosseous carcinoma of mandible: an update on review of literature with a case report

2010

Primary intraosseous carcinoma (PIOC) is a rare malignant neoplasm of the jaws which is locally aggressive with quite poor prognosis. Overall and disease free survival is poor with almost 50% patients failing within first 2 years of follow up and reason can be attributed to the delayed diagnosis. But knowledge of the clinical, radiographic and histopathologic features of PIOC allows accurate and early diagnosis of the lesion so that an early and appropriate treatment can be instituted for better prognosis. Here a typical case of PIOC of the mandible is presented and an attempt is made to discuss all possible differential diagnosis and an update on review of literature is presented. Our case…

What is the best surgical option for the resection of transverse colon cancer?

2019

Transverse colon is an infrequent localization of colon cancer and it is burdened by a poor prognosis. The principle of oncological radicality includes primary tumor resection with adequate lymphadenectomy. To date, there is still no consensus on which type of surgical resection perform in case of transverse colon cancer (TCC). Lymphatic drainage and vascularization of this section of the colon is highly variable presenting with different anatomical variants. Moreover, mobilization of the transverse colon can be particularly challenging in comparison to other colon tracts. Despite a lack of standardized definitions, three main surgical options are proposed: segmental colectomy of the transv…

L’ecologisme dels pobles. “Poca gent et dirà que és ecologista, però fem com si ho fórem perquè ho hem viscut de sempre”

2019

Aquest article desafia el sentit comú que ens informa que el desenvolupament socioeconòmic, al llarg de la història, ha comportat una millor consciència medi ambiental, una visió comunament acceptada que ha rebut suport teòric de la tesi postmaterialista. A partir d’un estudi qualitatiu –portat a terme a pobles que envolten el Delta de l’Ebre i l’Albufera de València— l’anàlisi d’enquestes que tracten temes mediambiental i l’anàlisi de les petjades ecològica i material, demostrarem com aquesta manera postmaterialista d’entendre el medi ambient, aliena la conscienciació mediambiental de les pràctiques i estils de vida. I el que és encara més importat, aliena la consciència mediambiental del …

Hospital Reform in Palermo

2023

A partire dal XV secolo, l'ospedale cessa di essere un riflesso della carità cristiana e diventa un veicolo per la gestione del bene comune. In precedenza, la diffusione della spiritualità influenzata dagli Ordini mendicanti aveva stimolato nuove forme di pietà e opere di carità più ampie, tra cui le visite ai malati, la gestione degli ospedali e la distribuzione di cibo e vestiario. Il tardo Medioevo vide un un cambiamento radicale. Gli ospedali divennero centri polifunzionali dedicati a vari tipi di cure. In linea con una tendenza osservata in tutta Europa, le principali città siciliane (Messina, Catania, Palermo, Siracusa e Trapani) adattarono i propri sistemi ospedalieri alle esigenze d…

Requirements elicitation methods based on interviews in comparison: A family of experiments

2020

Abstract Context There are several methods to elicit requirements through interviews between an end-user and a team of software developers. The choice of the best method in this context is usually on subjective developers’ preferences instead of objective reasons. There is a lack of empirical evaluations of methods to elicit requirements that help developers to choose the most suitable one. Objective This paper designs and conducts a family of experiments to compare three methods to elicit requirements: Unstructured Interviews, where there is no specific protocol or artifacts; Joint Application Design (JAD), where each member of the development team has a specific role; Paper Prototyping, w…