Search results for "porous materials"
showing 10 items of 46 documents
Ultrasonic characterisation of poroux materials
2017
International audience; Acoustic models of the acoustics of porous and perforated media involve a set of physical parameters. Some of the parameters, the tortusity, the viscous and thermal characteristic lengths are defined for a perfect incompressible and inviscid fluid saturating the porous medium. It is shown that ultrasonic propagation in air-saturated materials can be used to determine these parameters. A basic method involving air-coupled ultrasonic transducers is presented. Variants of this method and a practical implementation of one of these is proposed.
Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles
2015
[EN] Excessive apoptotic cell death is at the origin of several pathologies, such as degenerative disorders, stroke or ischemia-reperfusion damage. In this context, strategies to improve inhibition of apoptosis and other types of cell death are of interest and may represent a pharmacological opportunity for the treatment of cell-death-related disorders. In this scenario new peptide-containing delivery systems (solids S1-P1and S1-P2) are described based on meso-porous silica nanoparticles (MSNs) loaded with a dye and capped with the KKGDEVDKKARDEVDK (P1) peptide that contains two repeats of the DEVD target sequence that are selectively hydrolyzed by caspase3 (C3). This enzyme plays a central…
Synergetic effect of host-guest chemistry and spin crossover in 3D Hofmann-like metal-organic frameworks [Fe(bpac)M(CN)4] (M=Pt, Pd, Ni).
2012
The synthesis and characterization of a series of three-dimensional (3D) Hofmann-like clathrate porous metal-organic framework (MOF) materials [Fe(bpac)M(CN) 4] (M=Pt, Pd, and Ni; bpac=bis(4-pyridyl)acetylene) that exhibit spin-crossover behavior is reported. The rigid bpac ligand is longer than the previously used azopyridine and pyrazine and has been selected with the aim to improve both the spin-crossover properties and the porosity of the corresponding porous coordination polymers (PCPs). The 3D network is composed of successive {Fe[M(CN) 4]} n planar layers bridged by the bis-monodentate bpac ligand linked in the apical positions of the iron center. The large void between the layers, w…
Image processing techniques for the analysis of the micro-architecture of three-dimensional porous scaffolds
2011
Enzyme-responsive intracellular-controlled release using silica mesoporous nanoparticles capped with ε-poly-L-lysine.
2014
The synthesis and characterization of two new capped silica mesoporous nanoparticles for controlled delivery purposes are described. Capped hybrid systems consist of MCM-41 nanoparticles functionalized on the outer surface with polymer epsilon-poly-L-lysine by two different anchoring strategies. In both cases, nanoparticles were loaded with model dye molecule [Ru(bipy)(3)](2+). An anchoring strategy involved the random formation of urea bonds by the treatment of propyl isocyanate-functionalized MCM-41 nanoparticles with the lysine amino groups located on the epsilon-poly-L-lysine backbone (solid Ru-rLys-S1). The second strategy involved a specific attachment through the carboxyl terminus of…
Azobenzene Polyesters Used as Gate-Like Scaffolds in Nanoscopic Hybrid Systems
2012
The synthesis and characterisation of new capped silica mesoporous nanoparticles for on-command delivery applications is reported. Functional capped hybrid systems consist of MCM-41 nanoparticles functionalised on the external surface with polyesters bearing azobenzene derivatives and rhodamine¿B inside the mesopores. Two solid materials, Rh-PAzo8-S and Rh-PAzo6-S, containing two closely related polymers, PAzo8 and PAzo6, in the pore outlets have been prepared. Materials Rh-PAzo8-S and Rh-PAzo6-S showed an almost zero release in water due to steric hindrance imposed by the presence of anchored bulky polyesters, whereas a large delivery of the cargo was observed in the presence of an esteras…
Acoustic methods for measuring the porosities of porous materials incorporating dead-end pores
2013
International audience; The acoustic properties of porous materials containing dead-end (DE) pores have been proposed by Dupont et al. [J. Appl. Phys. 110, 094903 (2011)]. In the theoretical description, two physical parameters were defined (the dead-end porosity and the average length of the dead-end pores). With the knowledge of the open porosity (measured with non-acoustic methods), and the measurement of kinematic porosity (also called the Biot porosity in this article), it is possible to deduce the dead-end porosity. Two acoustic methods for measuring the Biot porosity for a wide range of porosities are proposed. These methods are based on acoustic transmission and on the low and high …
Characterization of porous absorbent materials
2012
International audience; Over the past twenty years, theoretical and experimental research on the acoustical properties of air-saturated porous materials for engineering applications has considerably progressed thanks to the contributions of many researchers in different institutes in the world. Accompanying the research on the acoustical properties of absorbent materials, new methods and experimental techniques were developed for the measurement of important physical parameters of these materials, necessary for the acoustic models. The attention is focused on the particularly important contributions of two laboratories: the Laboratoire dAcoustique de lUniversité du Maine (LAUM) in France …
Caractérisation physique de matériaux poreux pour l'étude des interactions acoustique/structure
2005
Cette thèse d'habilitation synthétise les dix ans de recherche qui suivirent ma thèse de doctorat dans les domaines des paramètres physiques et de l'acoustique des milieux poreux et des interactions fluide/squelette. Ce mémoire est divisé en trois parties principales A, B et C correspondant aux trois principales périodes de ma carrière scientifique: la période entre 1994 et 1997 passée au Laboratorium voor Akoestiek en Thermische Fysica de la K. U. Leuven en Belgique en collaboration avec le Laboratoire d'Acoustique de l'Université du Maine au Mans, la période entre 1997 et 2003 passée à Bradford (UK) en tant que chercheur (1997-2000) et les trois années passées à Hull (UK) en tant que maît…
Bidirectional Chemo-Switching of Spin State in a Microporous Framework
2009
The ins and outs of spin: Using the microporous coordination polymer {Fe(pz)[Pt(CN)(4)]} (1, pz=pyrazine), incorporating spin-crossover subunits, two-directional magnetic chemo-switching is achieved at room temperature. In situ magnetic measurements following guest vapor injection show that most guest molecules transform 1 from the low-spin (LS) state to the high-spin (HS) state, whereas CS(2) uniquely causes the reverse HS-to-LS transition.