Search results for "position"
showing 10 items of 6771 documents
Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement
2018
Tissue-specific effects of 17 beta-estradiol are delivered via both estrogen receptors and microRNAs (miRs). Menopause is known to affect the whole-body fat distribution in women. This investigation aimed at identifying menopause-and hormone replacement therapy (HRT)-associated miR profiles and miR targets in subcutaneous abdominal adipose tissue and serum from the same women. A discovery phase using array technology was performed in 13 women, including monozygotic twin pairs discordant for HRT and premenopausal young controls. Seven miRs, expressed in both adipose tissue and serum, were selected for validation phase in 34 women from a different cohort. An age/menopause-related increase of …
Comparative validity of the ASSO - Food Frequency Questionnaire for the web-based assessment of food and nutrients intake in adolescents
2015
Background : A new web-based food frequency questionnaire (the ASSO–FFQ) was developed within the ASSO Project funded by the Italian Ministry of Health. Objective : The aim of the present study is to assess the validity of the ASSO–FFQ at food groups, energy, and nutrients level. Design and subjects : The validation study compared the ASSO–FFQ against a weighted food record (WFR) measuring foods, beverages and supplements intake, compiled during the week following the ASSO–FFQ administration. Ninety-two subjects aged 14–17, recruited from secondary schools in Palermo (Italy), completed the ASSO–FFQ and WFR. The intake of 24 food groups, energy, and 52 nutrients were taken as main outcomes. …
Novel activities of safe-in-human broad-spectrum antiviral agents
2018
According to the WHO, there is an urgent need for better control of viral diseases. Re-positioning existing safe-in-human antiviral agents from one viral disease to another could play a pivotal role in this process. Here, we reviewed all approved, investigational and experimental antiviral agents, which are safe in man, and identified 59 compounds that target at least three viral diseases. We tested 55 of these compounds against eight different RNA and DNA viruses. We found novel activities for dalbavancin against echovirus 1, ezetimibe against human immunodeficiency virus 1 and Zika virus, as well as azacitidine, cyclosporine, minocycline, oritavancin and ritonavir against Rift valley feve…
Artroplastia de suspensión dinámica de Scheker en el tratamiento de la artrosis trapeciometacarpiana
2017
Objetivo Evaluar los resultados clínicos y radiográficos de una serie de pacientes sometidos a una artroplastia de Scheker. Material y Método Estudio descriptivo de 16 pacientes con artrosis TMC. Se valoró el estado clínico y funcional según el cuestionario DASH, la movilidad del pulgar según la escala de Kapandji y el dolor según la escala visual analógica (EVA). A nivel radiográfico, se cuantificó el colapso del espacio remanente tras la exéresis del trapecio. Resultados La edad promedio de los pacientes fue 64,9 años, 81% fueron mujeres. El tiempo de seguimiento medio fue de 19 meses. La puntuación DASH preoperatoria fue de 67,68 puntos y postoperatoria 34,88 (p < 0.001). La puntuaci…
Human Phageprints: A high-resolution exploration of oral phages reveals globally-distributed phage families with individual-specific and temporally-s…
2019
AbstractMetagenomic studies have revolutionized the study of novel phages. However these studies trade the depth of coverage for breadth. In this study we show that the targeted sequencing of a phage genomic region as small as 200-300 base pairs, can provide sufficient sequence diversity to serve as an individual-specific barcode or “Phageprint”. The targeted approach reveals a high-resolution view of phage communities that is not available through metagenomic datasets. By creating instructional videos and collection kits, we enabled citizen scientists to gather ∼700 oral samples spanning ∼100 individuals residing in different parts of the world. In examining phage communities at 6 differen…
Hybrid State Feedback Position-Force Control of Hydraulic Cylinder
2019
A hybrid position-force control is proposed using a unified state feedback controller in combination with feedforward dead-zone compensation. Dead-zone compensator was constructed as inverse of the identified static map while the state feedback gains were obtained using a numerical optimization routine. An accurate state-space model affine in states and control, derived in a previous work, was used for closed-loop simulations and control tuning. A trigger event for automatic switching between position and force control was defined and integrated into overall control architecture alongside with a feedforward low-pass filter reducing high frequency components in the control signal. Experiment…
Numerical Study on the Heading Misalignment and Current Velocity Reduction of a Vessel-Shaped Offshore Fish Farm
2019
Recently, the concept of a vessel-shaped fish farm was proposed for open sea applications. The fish farm comprises a vessel-shaped floater, five fish cages, and a single-point mooring system. Such a system weathervanes, and this feature increases the spread area of fish waste. Still, the downstream cages may experience decreased exchange of water flow when the vessel heading is aligned with the current direction, and fish welfare may be jeopardized. To ameliorate the flow conditions, a dynamic positioning (DP) system may be required, and its power consumption should relate to the heading misalignment. This paper proposes an integrated method for predicting the heading misalignment between t…
Quantification of propagating and standing surface acoustic waves by stroboscopic X-ray photoemission electron microscopy.
2018
The quantification of surface acoustic waves (SAWs) in LiNbO3 piezoelectric crystals by stroboscopic X-ray photoemission electron microscopy (XPEEM), with a temporal smearing below 80 ps and a spatial resolution below 100 nm, is reported. The contrast mechanism is the varying piezoelectric surface potential associated with the SAW phase. Thus, kinetic energy spectra of photoemitted secondary electrons measure directly the SAW electrical amplitude and allow for the quantification of the associated strain. The stroboscopic imaging combined with a deliberate detuning allows resolving and quantifying the respective standing and propagating components of SAWs from a superposition of waves. Furth…
Effects of Food Label Health and Nutrition Claims on Consumer Perceptions
2009
Two experiments are reported that examined consumers' perceptions of food package labels where health and nutrition claims were present and where they had been removed. Unlike previous studies examining the influence of information on perception, realistic materials were used. This was accomplished by presenting information on a computer as photo-realistic images of packages where claims had been removed by editing to give a without-claims condition. Automatic presentation of materials and data collection meant participants proceeded through the computer questionnaire without the presence of an experimenter. The experiment was conducted with both British and French consumers. No significant…