Search results for "positron"
showing 10 items of 1346 documents
Hunting for the high-affinity state of G-protein-coupled receptors with agonist tracers: Theoretical and practical considerations for positron emissi…
2019
Abstract The concept of the high‐affinity state postulates that a certain subset of G‐protein‐coupled receptors is primarily responsible for receptor signaling in the living brain. Assessing the abundance of this subset is thus potentially highly relevant for studies concerning the responses of neurotransmission to pharmacological or physiological stimuli and the dysregulation of neurotransmission in neurological or psychiatric disorders. The high‐affinity state is preferentially recognized by agonists in vitro. For this reason, agonist tracers have been developed as tools for the noninvasive imaging of the high‐affinity state with positron emission tomography (PET). This review provides an…
Evolution of Free Volumes in Polycrystalline BaGa2O4 Ceramics Doped with Eu3+ Ions
2021
H.K. and Y.K. would like to thank A. Ingram for assistance in PAL experiments. The authors thank E.A. Kotomin and M. Brik for the many useful discussions. The research was (partly) performed in the Institute of Solid State Physics, University of Latvia ISSP UL. ISSP UL as the Center of Excellence is supported through the Framework Program for European universities Union Horizon 2020, H2020-WIDESPREAD-01–2016–2017-TeamingPhase2 under Grant Agreement No. 739508, CAMART2 project.
Positron Annihilation in IR Transmitting GeS₂-Ga₂S₃ Glasses
2015
Positron annihilation lifetime spectroscopy combined with Doppler broadening of annihilation radiation was applied to study free-volume entities in GeS2-Ga2S3 glasses affected by Ga additions. It is shown that Ga-related void sub-system plays a decisive role in positron trapping process, while the overall density variation is defined mainly by Ge-related sub-system. These results serve as basis for new characterization route for inner free-volume structure of these glasses.
Search for the decayB¯0→Λc+p¯pp¯
2014
We report a search for the decay B^0 → Λ^+_cppp. Using a data sample of 471×10^6 BB pairs collected with the BABAR detector at the PEP-II2 storage ring at SLAC, we find no events and set an upper limit on the branching fraction B(B^0 → Λ^+_cppp)×^(B(Λ^+_c→pK^−π^+))_(0.050) <2.8×10^(−6) at 90% C.L., where we have normalized B(Λ^+_c → pK^−π^+) to the world average value.
Various types of polysiloxanes studied by positron annihilation lifetime spectroscopy
2014
Abstract In the work, linear poly(vinylsiloxanes) with regular distributions of vinyl groups along chains, the networks obtained by their hydrosilylation with various hydrogensiloxanes, products of pyrolysis of such networks as well as the networks prepared via reaction of low-molecular siloxanes have been studied by positron anihilation lifetime spectroscopy (PALS). Based on free volume sizes determined by this method, relations between cross-link densities in the investigated systems have been established. They have been compared with the results of swelling experiments conducted in the work and to efficiency of cross-linking reaction evaluated in our previous FTIR investigations of the s…
Critical single proximal left arterial descending coronary artery stenosis to mimic chronic myocardial ischemia: a new model induced by minimal invas…
2008
<i>Background/Aims:</i> The present report examines a new pig model for progressive induction of high-grade stenosis, for the study of chronic myocardial ischemia and the dynamics of collateral vessel growth. <i>Methods:</i> Thirty-nine Landrace pigs were instrumented with a novel experimental stent (GVD stent) in the left anterior descending coronary artery. Eight animals underwent transthoracic echocardiography at rest and under low-dose dobutamine. Seven animals were examined by nuclear PET and SPECT analysis. Epi-, mid- and endocardial fibrosis and the numbers of arterial vessels were examined by histology. <i>Results:</i> Functional analysis showed a…
Role of positron emission tomography (PET) in advanced stage non-small cell lung cancer patients treated with cisplatin-based doublets
2008
Effect of inter-crystal scatter on estimation methods for random coincidences and subsequent correction.
2008
Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Simulated singles list-mode data of the MADPET-II small animal PET scanner were used as input. The simulations have been performed using the GATE simulation toolkit. Several sources with different geometries have been employed. We evaluated the number of random events using three methods: delayed window (DW), singles rate (SR) and time histogram fitting (TH). Since the GATE simula…
Measurement of Branching Fractions and Charge Asymmetries inB±→ρ±π0andB±→ρ0π±Decays, and Search forB0→ρ0π0
2004
We present measurements of branching fractions and charge asymmetries in $B$-meson decays to ${\ensuremath{\rho}}^{+}{\ensuremath{\pi}}^{0}$, ${\ensuremath{\rho}}^{0}{\ensuremath{\pi}}^{+}$, and ${\ensuremath{\rho}}^{0}{\ensuremath{\pi}}^{0}$. The data sample comprises $89\ifmmode\times\else\texttimes\fi{}{10}^{6}$ $\ensuremath{\Upsilon}(4S)\ensuremath{\rightarrow}B\overline{B}$ decays collected with the BABAR detector at the PEP-II asymmetric-energy $B$ Factory at SLAC. We find the charge-averaged branching fractions $\mathcal{B}({B}^{+}\ensuremath{\rightarrow}{\ensuremath{\rho}}^{+}{\ensuremath{\pi}}^{0})=[10.9\ifmmode\pm\else\textpm\fi{}1.9\mathrm{(}\mathrm{s}\mathrm{t}\mathrm{a}\mathrm{…
Functional Changes in Brain Activity After Hypnosis: Neurobiological Mechanisms and Application to Patients with a Specific Phobia—Limitations and Fu…
2019
Studies of brain-plasticity changes in hypnosis using functional magnetic resonance imaging (fMRI), positron-emission-tomography (PET) and electroencephalography (EEG) were reviewed. The authors found evidence in those studies that hypnosis is a powerful and successful method for inhibiting the reaction of the fear circuitry structures. Limitations of the studies were critically discussed, and implications for future research were made. The authors are currently using a portable fNIRS apparatus to integrate the scanning device into real life situations in medical practice. Their aim is to disentangle the neuronal mechanisms and physiological correlates in patients with severe fear of medica…