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showing 10 items of 6213 documents

Long-term evaluation of quality of life and gastrointestinal well-being after segmental colo-rectal resection for deep infiltrating endometriosis (EN…

2019

Purposes: The primary objective is to assess the long-term quality of life (QoL) and gastrointestinal well-being in patients with endometriosis (DIE) who underwent segmental resection (SR), through specific questionnaires focused on endometriosis and specific gastrointestinal evaluation. The secondary objectives are represented by the evaluation of peri-operative and post-operative outcomes of the procedure. Methods: This observational cohort study ENDO-RESECT (ClinicalTrials.gov ID: NCT03824054) reports all clinical data about women who underwent SR for DIE between October 2005 and November 2017. In the part of the study dedicated to the QoL assessment, the questionnaires adopted were the …

AdultQuality of lifemedicine.medical_specialtyAbdominal painConstipationAdolescentGastrointestinal DiseasesEndometriosisEndometriosisSegmental colo-rectal resectionHospital Anxiety and Depression ScaleGastrointestinal symptomsCohort StudiesYoung AdultPostoperative ComplicationsQuality of lifePregnancySurveys and QuestionnairesInternal medicineGastrointestinal symptommedicineHumansDeep infiltrating endometriosis; Gastrointestinal symptoms; Intestinal endometriosis; Personalized medicine; Quality of life; Segmental colo-rectal resection; Adolescent; Adult; Cohort Studies; Colorectal Neoplasms; Endometriosis; Female; Gastrointestinal Diseases; Humans; Middle Aged; Postoperative Complications; Pregnancy; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Young Adultbusiness.industryIntestinal endometriosiObstetrics and GynecologyGeneral MedicineMiddle Agedmedicine.diseasePersonalized medicineDeep infiltrating endometriosiTreatment OutcomeSettore MED/40 - GINECOLOGIA E OSTETRICIADeep infiltrating endometriosisDeep infiltrating endometriosis; Intestinal endometriosis; Segmental colo-rectal resection; Quality of life; Gastrointestinal symptoms; Personalized medicineDefecationFemaleIntestinal endometriosisSegmental resectionmedicine.symptomColorectal NeoplasmsbusinessCohort study
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Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properti…

2000

Hemofiltrate CC chemokine (HCC)-1 is a recently described human chemokine that is constitutively expressed in numerous tissues and is present at high concentrations in normal plasma. Using a cell line expressing CC chemokine receptor (CCR)5 as a bioassay, we isolated from human hemofiltrate an HCC-1 variant lacking the first eight amino acids. HCC-1[9–74] was a potent agonist of CCR1, CCR3, and CCR5 and promoted calcium flux and chemotaxis of T lymphoblasts, monocytes, and eosinophils. It also blocked entry of HIV-1 strains using CCR5 as coreceptor. Limited tryptic digestion of HCC-1 generated the active variant. Conditioned media from several tumor cell lines activated HCC-1 with a high ef…

AdultReceptors CCR5Anti-HIV AgentsReceptors CCR3Molecular Sequence DataImmunologyReceptors CCR1C-C chemokine receptor type 6BiologyChemokine receptorEndopeptidasesHumansImmunology and AllergyCCL17Amino Acid SequenceCalcium SignalingCCL15CCL13endopeptidaseChemotactic FactorsHIVBlood ProteinsMolecular biologyPeptide FragmentsChemotaxis LeukocyteBiochemistryChemokines CCCulture Media ConditionedXCL2Biological AssayReceptors ChemokineOriginal ArticleCC chemokine receptorsProtein Processing Post-TranslationalCCL21Journal of Experimental Medicine
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Mesh or no mesh: a hamletic dilemma to prevent Renal Allograft Compartment Syndrome (RACS)

2014

Tension-free muscle closure is essential in kidney transplantation, both in adult and pediatric patients. Tight muscle closure may lead to renal allograft compartment syndrome either due to compression of the renal parenchyma or due to kinking of the renal vessels. It may also cause kinking of the transplant kidney ureter, wound dehiscence and incisional hernia. Many techniques have been proposed in an attempt to achieve tension-free closure. There is a wrong belief among surgeons that using prosthetic mesh may increase the incidence of infective complications in these immunosuppressed patients. Also, there is fear that one is not able to monitor the renal graft by ultrasound and perform bi…

AdultRenal Allograft Compartment syndrome (RACS)Evidence-Based MedicineAbdominal WallSuture TechniquesPost transplant incisional herniaRenal transplantationSurgical MeshCompartment SyndromesKidney TransplantationAbdominal mesh closureSettore MED/18 - Chirurgia GeneraleTreatment OutcomeHumansChildPolytetrafluoroethylene
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The Patient and Observer Scar Assessment Scale to Evaluate the Cosmetic Outcomes of the Robotic Single-Site Hysterectomy in Endometrial Cancer

2017

ObjectiveThe objective of this study was to evaluate the cosmetic outcome of robotic single-site hysterectomy (RSSH) in early-stage endometrial cancer.MethodsWe prospectively collected patient demographics, operative times, complications, pathologic results, and length of stay on all patients who underwent RSSH for early-stage endometrial cancer. The Patient and Observer Scar Assessment Scale (POSAS) was used for the evaluation of the cosmetic outcome.ResultsForty-five patients were included in our study from January 2012 to October 2015. The median age of patients was 63 years (range, 35–84 years), and the median body mass index was 26.5 kg/m2 (range, 18–39 kg/m2). No laparoscopic/laparoto…

AdultRobotic Surgical Proceduremedicine.medical_specialtymedicine.medical_treatmentPOSASScarsHysterectomyCicatrix03 medical and health sciences0302 clinical medicineEndometrial cancerRobotic Surgical ProceduresObstetrics and gynaecologymedicineHumansEndometrial NeoplasmMass indexProspective StudiesProspective cohort studyAgedAged 80 and over030219 obstetrics & reproductive medicineHysterectomybusiness.industryEndometrial cancerObstetrics and GynecologyPostoperative complicationMiddle Agedmedicine.diseaseEndometrial NeoplasmsSurgeryRobotic single-site hysterectomyProspective StudieOncology030220 oncology & carcinogenesisFemaleMedian bodymedicine.symptombusinessHumanInternational Journal of Gynecologic Cancer
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A minimal limit-cycle model to profile movement patterns of individuals during agility drill performance: Effects of skill level.

2015

Identification of control strategies during agility performance is significant in understanding movement behavior. This study aimed at providing a fundamental mathematical model for describing the motion of participants during an agility drill and to determine whether skill level constrained model components. Motion patterns of two groups of skilled and unskilled participants (n = 8 in each) during performance of a forward/backward agility drill modeled as limit-cycles. Participant movements were recorded by motion capture of a reflective marker attached to the sacrum of each individual. Graphical and regression analyses of movement kinematics in Hooke’s plane, phase plane and velocity prof…

AdultSacrumComputer scienceMovementBiophysicsExperimental and Cognitive PsychologyKinematicsAthletic PerformanceMotion captureMotion (physics)RunningSkill levelMotionYoung AdultOscillometryHumansOrthopedics and Sports MedicineComputer Simulationta315Postural BalanceSimulationVan der Pol oscillatorDrillMovement (music)Limit-cycle modelGeneral MedicineVariance (accounting)Phase planeModels TheoreticalMotor processesBiomechanical PhenomenaPhysical FitnessNonlinear dynamicsCalibrationAgilityRegression AnalysisPsychomotor PerformanceHuman movement science
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Autonomic regulation of nasal vessels during changes in body position

1994

The effects of postural changes on nasal airflow and nasal capillary blood flow were investigated in 15 healthy volunteers. Measurements were performed following nasal application of saline solution (control), the alpha-1 receptor antagonist prazosin, the alpha-2 receptor antagonist yohimbine, and after application of both prazosin and yohimbine. Nasal airflow in the control experiments did not significantly differ in the upright (362 +/- 166 ml/s), dorsally recumbent (350 +/- 167 ml/s) and 70 degrees head down position (311 +/- 167 ml/s). Following application of prazosin, nasal airflow was reduced to 223 +/- 121 ml/s in the upright position. Prazosin treatment significantly reduced nasal …

AdultSupine positionmedicine.medical_treatmentPostureNoseSodium ChlorideNasal congestionHead-Down TiltPlacebosLaser-Doppler FlowmetrySupine Positionotorhinolaryngologic diseasesPrazosinmedicineHumansSalineAdministration Intranasalmedicine.diagnostic_testbusiness.industryAirway ResistanceMicrocirculationYohimbinePrazosinGeneral MedicineBlood flowReceptors Adrenergic alpharespiratory systemLaser Doppler velocimetryCapillariesYohimbineOtorhinolaryngologyAnesthesiaRhinomanometrymedicine.symptomPulmonary Ventilationbusinessmedicine.drugEuropean Archives of Oto-Rhino-Laryngology
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Free amino acids in preterm and term milk from mothers delivering appropriate- or small-for-gestational-age infants.

1989

Free amino acids were quantitated in human milk collected during the first month postpartum from mothers of appropriate preterm (26-32 and 33-36 wk gestation) and term (small or appropriate-for-gestational-age) infants. Glutamic acid and taurine were the most abundant amino acids in all four groups at all stages of lactation. The ratio of essential to nonessential amino acids was higher in colostrum than in mature milk although the total amino acid level of mature milk was double that of the colostrum. Nonprotein amino acids amount to approximately 40% of the free-amino acid pool in colostrum. Differences in the content and changes in free-amino acid levels during lactation among the groups…

AdultTaurinemedicine.medical_specialtyMedicine (miscellaneous)Breast milkchemistry.chemical_compoundfluids and secretionsAnimal scienceObstetric Labor PrematurePregnancyInternal medicineLactationMedicineHumansLactationAmino Acidschemistry.chemical_classificationNutrition and DieteticsMilk Humanbusiness.industryColostrumInfant Newbornfood and beveragesGestational agemedicine.diseaseAmino acidEndocrinologymedicine.anatomical_structurechemistryInfant Small for Gestational AgeSmall for gestational ageColostrumFemalebusinessPostpartum periodThe American journal of clinical nutrition
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How can droplet formation occur in endodontically treated teeth during bonding procedures?

2008

PURPOSE: The aim of this in vivo study was to clarify how blistering formation occurs along intraradicular dentin bonded interfaces. MATERIALS AND METHODS: Patients were selected and post space was prepared in vivo in endodontically treated teeth. Post space was etched, dried with ethanol, and bonded with one of the following adhesive systems: All Bond 2, XP-Bond, Clearfil SE Bond, Xeno III. The four adhesives were considered as representative of each bonding system class. An additional group was prepared with phosphoric acid treatment + application of Pre-Bond unfilled resin of All Bond 2, without the use of the primer agent. Etching was avoided for self-etching materials. Replicas of the …

AdultTooth NonvitalEthanolSurface PropertiesDental BondingMiddle Agedadhesive permeability simplified adhesive root canal droplet formationResin CementsAcid Etching DentalSettore MED/28 - Malattie OdontostomatologicheDentin-Bonding AgentsDentinMicroscopy Electron ScanningSolventsHumansMethacrylatesReplica TechniquesPhosphoric AcidsDental Pulp CavityAgedPost and Core Technique
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Objectively recorded physical activity in pregnancy and postpartum in a multi-ethnic cohort: association with access to recreational areas in the nei…

2015

Background Physical activity may reduce the risk of adverse pregnancy outcomes; however, compared to non-pregnant women, a lower proportion of pregnant women meet the physical activity guidelines. Our objectives were to explore overall changes and ethnic differences in objectively recorded moderate-to-vigorous intensity physical activity (MVPA) during pregnancy and postpartum and to investigate the associations with objective and perceived access to recreational areas. Methods We analysed 1,467 person-observations from 709 women in a multi-ethnic population-based cohort, with MVPA data recorded with the SenseWear™ Pro3 Armband in early pregnancy (mean gestational week (GW) 15), mid-pregnanc…

AdultUrban PopulationParks RecreationalPhysical fitnessPopulationEthnic groupMedicine (miscellaneous)Physical Therapy Sports Therapy and Rehabilitation:Medisinske Fag: 700::Klinisk medisinske fag: 750::Gynekologi og obstetrikk: 756 [VDP]Ethnic groupsCohort Studies03 medical and health sciences0302 clinical medicineNeighbourhoodsResidence CharacteristicsUrban planningPregnancyEnvironmental healthmedicineEthnicityHumans030212 general & internal medicineCitieseducationExercisegeographic information systemsPregnancyeducation.field_of_studyNutrition and Dieteticsbusiness.industryNorwayPhysical activityResearchPostpartum Period030229 sport sciencesmedicine.diseasePeer reviewVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Gynekologi og obstetrikk: 756CohortFemalebusinesshuman activitiesPostpartum periodCohort study
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Laparoscopic Radical Hysterectomy After Concomitant Chemoradiation in Locally Advanced Cervical Cancer: A Prospective Phase II Study

2015

Abstract Study Objective To assess the feasibility of total robotic radical surgery (TRRS) in patients with locally advanced cervical cancer (LACC) who receive chemoradiation therapy (CT/RT). Design A prospective (preplanned) study of a nonrandomized controlled trial (Canadian Task Force classification level 2). Setting Catholic University of the Sacred Hearth, Rome, Italy. Patients Between September 2013 and January 2016, a total of 40 patients with LACC (Federation Internationale de Gynecologie et d'Obstetrique stage IB2–III) were enrolled in the study. Interventions Robotic radical hysterectomy (RRH) plus pelvic and/or aortic lymphadenectomy was attempted within 6 weeks after CT/RT. The …

AdultUterine Cervical Neoplasmmedicine.medical_specialtymedicine.medical_treatmentUterine Cervical NeoplasmsHysterectomyPostoperative ComplicationsmedicineRadical hysterectomyHumansProspective StudiesCervical cancer; Laparoscopy; Neoadiuvant chemoradiation; Radical hysterectomy; Adult; Aged; Carcinoma; Squamous Cell; Chemoradiotherapy; Adjuvant; Cisplatin; Feasibility Studies; Female; Humans; Italy; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence; Local; Postoperative Complications; Prospective Studies; Uterine Cervical Neoplasms; Hysterectomy; Laparoscopy; Lymph Node ExcisionRadical surgeryRadical HysterectomyProspective cohort studyNeoadjuvant therapyAgedCervical cancerHysterectomybusiness.industryMedicine (all)Obstetrics and GynecologyLaparoscopic Radical HysterectomyPerioperativeChemoradiotherapy AdjuvantMiddle Agedmedicine.diseaseNeoadjuvant TherapySurgeryFeasibility StudieProspective StudieSettore MED/40 - GINECOLOGIA E OSTETRICIAItalyCervical cancerNeoadiuvant chemoradiationCarcinoma Squamous CellFeasibility StudiesLymph Node ExcisionLymphadenectomyFemaleLaparoscopyPostoperative ComplicationCisplatinNeoplasm Recurrence LocalbusinessHuman
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