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showing 10 items of 6213 documents

Imaging of Ventriculoperitoneal Shunt Complications: Comparison of Whole Body Low-Dose Computed Tomography and Radiographic Shunt Series.

2016

OBJECTIVE To determine diagnostic value and radiation exposure of low-dose computed tomography (LD-CT) compared to radiographic shunt series (SS) for the detection of ventriculoperitoneal (VP) shunt complications. METHODS Fourteen VP shunts were implanted in 7 swine cadavers. Mechanical complications were induced in 50% of VP shunts. Low-dose CT (80 kVp, 10 mAs, Pitch = 1.5) and SS were acquired. Dose area product (DAP) and effective doses for SS and LD-CT were collected. Scoring of diagnostic confidence and blinded readings of SS and CT data were performed. RESULTS The sensitivity of LD-CT was high (0.97; 95% confidence interval, 0.91-1.00) with excellent interobserver agreement (κ = 0.88)…

medicine.medical_specialtySwineRadiographyComputed tomographyRadiation DosageEffective dose (radiation)Sensitivity and SpecificityVentriculoperitoneal Shunt030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRadiation ProtectionmedicineAnimalsRadiology Nuclear Medicine and imagingMedical physicsSingle-Blind MethodWhole Body Imagingmedicine.diagnostic_testbusiness.industryLow doseReproducibility of ResultsRadiation ExposureConfidence intervalRadiographic Image EnhancementDose area productRadiographic Image Interpretation Computer-AssistedTomographybusinessNuclear medicineTomography X-Ray Computed030217 neurology & neurosurgeryShunt (electrical)Journal of computer assisted tomography
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Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats.

2014

In the developing cerebral cortex, the marginal zone (MZ), consisting of early-generated neurons such as Cajal-Retzius cells, plays an important role in cell migration and lamination. There is accumulating evidence of widespread excitatory neurotransmission mediated by γ-aminobutyric acid (GABA) in the MZ. Cajal-Retzius cells express not only GABAA receptors but also α2/β subunits of glycine receptors, and exhibit glycine receptor-mediated depolarization due to high [Cl(-)]i. However, the physiological roles of glycine receptors and their endogenous agonists during neurotransmission in the MZ are yet to be elucidated. To address this question, we performed optical imaging from the MZ using …

medicine.medical_specialtyTaurinemicrodialysisNeurotransmissionBiologylcsh:RC321-571Cellular and Molecular Neurosciencechemistry.chemical_compoundGABAInternal medicinemedicineNKCC1Channel blockerOriginal Research ArticleGlycine receptorGABA Agonistslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryGABAA receptorGlutamate receptorGABAA receptorDepolarizationEndocrinologychemistryExcitatory postsynaptic potentialBiophysicsmarginal zoneglycine receptortaurineNeuroscienceFrontiers in cellular neuroscience
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Posterior variant of alien limb syndrome with sudden clinical onset as self-hitting associated with thalamic stroke

2020

We present a case of sudden postischaemic onset of alien limb syndrome, with unintentional self-injury. Alien limb syndrome is an uncommon neurological disorder featured by uncontrolled and involuntary movements of a limb. Three variants of alien limb syndrome have been described: the anterior, featured by grasping of surrounding objects, the callosal, presenting with intermanual conflict, and the posterior, associated with involuntary levitation of the limb. Our patient suffered from an acute presentation of the posterior variant of the alien limb syndrome, resulting from an isolated thalamic stroke which was documented using 24-h computed tomography brain scan. Only one previous case of a…

medicine.medical_specialtyThalamic strokeAlien handNeurological disorderClinical onsetlcsh:RC346-42903 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationNeuroimagingmedicineSingle Case - General Neurology030212 general & internal medicineCerebrovascular diseaseStrokelcsh:Neurology. Diseases of the nervous systemInvoluntary movementbusiness.industryPosterior variant of alien limb syndromemedicine.diseaseSelf hittingbody regionsStrokeThalamic strokeSettore MED/26 - NeurologiaNeurology (clinical)Presentation (obstetrics)business030217 neurology & neurosurgery
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Static Crow’s Feet Treated with Voltaic Arc Dermabrasion (Atmospheric Plasma): Post-Operative Pain Assessment by Thermal Infrared Imaging

2021

Background: In the literature, several strategies have been described for the treatment of unaesthetic marks on the face resulting from the aging processes. The atmospheric plasma procedure is a non-invasive, inexpensive technique proposed for the rejuvenation of facial tissues. The aim of this study was to evaluate the performance of voltaic arc dermabrasion (VAD) for the treatment of static crow’s feet of the periorbital area. Methods: The crow’s feet of 135 patients (127 female and 8 male) were treated using the VAD technique. The perioperative skin temperature measurement was assessed using an Infrared Temperature sensor. The pain was measured using the Visual Analogic Score (VAS) at 1 …

medicine.medical_specialtyTherapeutic treatmentmedicine.medical_treatmentskin rejuvenationArticle030207 dermatology & venereal diseases03 medical and health sciencesCrow's feet0302 clinical medicinePatient satisfactionMedicinedermabrasion030223 otorhinolaryngologyThermal infraredbusiness.industryDermabrasionRGeneral MedicinePerioperativevoltaic arc dermabrasionSurgerycrow’s feetVADMedicinebusinessatmospheric plasmaPost operative painGrading scaleJournal of Clinical Medicine
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Water maze performance, exploratory activity, inhibitory avoidance and hippocampal plasticity in aged superior and inferior learners

2002

In 28- to 30-month-old rats, in vitro short-term and long-term potentiation (STP and LTP) were measured in area CA1 of the hippocampus in seven superior and seven inferior learners, that were selected from a pool of 40 rats based on water maze escape performance over a period of 9 days. The aim was to examine whether levels of STP and LTP could account for group differences in learning of water maze escape, spatial preference and wall (thigmotaxis)-avoidance and in short-term retention of an inhibitory avoidance task. There was no significant group difference in open-field exploration, i.e. the number of rearings. In contrast to expectation, the superior and inferior learners did not differ…

medicine.medical_specialtyThigmotaxisPreference learningGeneral NeuroscienceHippocampusLong-term potentiationWater mazeHippocampal formationAudiologyInhibitory postsynaptic potentialOpen fieldDevelopmental psychologynervous systemmedicinePsychologyEuropean Journal of Neuroscience
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Ultrasound-guided spinal fracture repositioning

1998

The management of narrowing spinal fragments in the operative treatment of spinal fractures remains an open question, in particular when the procedure is performed by a posterior approach. This article describes the use of intraoperative ultrasonography during spinal surgery. From 1990 to 1997, 116 spinal fractures were treated operatively at our clinic. Stabilization of the spine was achieved with the AO fixateur interne and the AO USS, respectively (Synthes, D-79224, Umkirch, Germany). For 60 cases who had a fractured posterior vertebral surface dislocated into the spinal canal, we used intraoperative ultrasonography to monitor the repositioning of the narrowing fragments. The patients un…

medicine.medical_specialtyThoracic VertebraePosterior approachIntraoperative ultrasoundFracture Fixation InternalIntraoperative PeriodSpinal StenosisSpinal fractureHumansMedicineSpinal canalRachisRetrospective StudiesUltrasonography Doppler DuplexLumbar VertebraeSpinalisbusiness.industryReproducibility of Resultsmedicine.diseaseUltrasound guidedmedicine.anatomical_structureSpinal FracturesSurgeryRadiologyTomography X-Ray ComputedbusinessSpinal CanalAbdominal surgerySurgical Endoscopy
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Long-term outcome after urinary diversion using the ileocecal segment in children and adolescents: Complications of the efferent segment.

2016

Long-term outcomes are of special concern in children after urinary diversion. In a single institution study we evaluated retrospectively the long-term outcomes of urinary diversion in children, in whom the ileocecal segment had been used, in respect to complications of the efferent segment.The Mainz pouch was used in 107 children for continent urinary diversion. Indications were neurogenic bladder (53%, 57/107), exstrophy-epispadias complex (25%, 27/107), malignancy (13%, 14/107), and others (9%, 9/107). Continent cutaneous diversion was performed in 95 patients, and 12 patients received bladder augmentation/substitution with a continent cutaneous stoma. As efferent segment, we used the in…

medicine.medical_specialtyTime FactorsAdolescentUrologymedicine.medical_treatmentUrinary Bladder030232 urology & nephrologyConstriction PathologicUrinary Diversiondigestive system03 medical and health sciences0302 clinical medicinePostoperative ComplicationsStoma (medicine)IleummedicineHumansChildCecumRetrospective Studiesbusiness.industryUrinary diversionUrinary Bladder DiseasesSurgical Stomasmedicine.diseaseAppendixSurgeryStenosismedicine.anatomical_structureTreatment OutcomeBladder augmentation030220 oncology & carcinogenesisChild PreschoolPediatrics Perinatology and Child HealthPouchComplicationbusinessContinent Urinary DiversionJournal of pediatric urology
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Serum sphingomyelin levels are related to the clearance of postprandial remnant-like particles.

2005

It is known that sphingomyelin (SM) content is higher in apolipoprotein B-containing particles (BLps) than in high density lipoproteins and that BLp levels, including chylomicrons and their remnant particles, are positively related to atherosclerosis. To evaluate the relationship between serum SM and postprandial remnant particle levels, we determined SM, triglyceride (TG), and cholesterol levels in serum and in remnant-like particles (RLPs) before and 3, 5, 7, and 10 h after a high-fat meal in 31 healthy subjects. We found that serum SM, like serum TG, was increased to its maximum 3 h after fat loading and then gradually decreased to basal levels after 10 h. More important, we determined t…

medicine.medical_specialtyTime FactorsApolipoprotein BArteriosclerosisQD415-436Biochemistrychemistry.chemical_compoundEndocrinologylipidInternal medicineChylomicronsmedicineHumansTriglyceridesApolipoproteins BbiologyTriglycerideCholesterollipoproteinCholesterol HDLCell BiologyArteriosclerosismedicine.diseasePostprandial PeriodSphingomyelinsEndocrinologyPostprandialCholesterolchemistrybiology.proteinatherosclerosisSphingomyelinLipoproteins HDLBiomarkersChylomicronLipoproteinJournal of lipid research
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Absorption of protein in the early postoperative period in chronic conscious dogs.

1988

Postoperative alterations in amino acid exchange across the intestinal tract and in the capacity for protein absorption were investigated in a chronic canine model. Changes in postoperative splanchnic amino acid exchange consisted of a temporary decrease of total splanchnic amino acid release, including a significant reduction in alanine production, and an increase in glutamine consumption. Contrary to results under stable metabolic conditions, branched chain amino acids were also taken up by the intestine in the early postoperative period. The changes in postoperative amino acid exchange were not, however, reflected by a corresponding alteration in protein transport capacity. The absorptiv…

medicine.medical_specialtyTime FactorsConsciousnessPeriod (gene)Absorption (skin)HydrolysateCellular and Molecular NeuroscienceDogsInternal medicinemedicineAnimalsPostoperative PeriodAmino AcidsIntestinal MucosaMolecular BiologyPharmacologyAlaninechemistry.chemical_classificationChemistryProteinsCell BiologyTransport proteinAmino acidGlutaminePortal SystemEndocrinologyBiochemistryIntestinal AbsorptionRegional Blood FlowMolecular MedicineSplanchnicExperientia
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Influence of long-term postmenopausal hormone-replacement therapy on estimated structural bone strength: A study in discordant monozygotic twins

2010

Although postmenopausal hormone-replacement therapy (HRT) is known to prevent fractures, knowledge on the influence of long-term HRT on bone strength and its determinants other than areal bone mineral density is scarce. This study used a genetically controlled design with 24 monozygotic female twin pairs aged 54 to 72 years in which one cotwin was using HRT (mean duration 8 years) and the other had never used HRT. Estimated bone strength, cross-sectional area, volumetric bone mineral density, bone mineral mass, and cross-sectional density and mass distributions were assessed in the tibial shaft, distal tibia, and distal radius with peripheral computed tomography (pQCT). In the tibial shaft,…

medicine.medical_specialtyTime FactorsEndocrinology Diabetes and Metabolismmedicine.medical_treatmentDentistryMonozygotic twin030209 endocrinology & metabolismBone and Bones03 medical and health sciences0302 clinical medicineBone strengthBone DensitymedicineHumansPostmenopausal Hormone Replacement TherapyOrthopedics and Sports Medicineta315Aged030304 developmental biologyBone mineral0303 health sciencesPostmenopausal womenAnthropometrybusiness.industryEstrogen Replacement Therapyta3141Hormone replacement therapy (menopause)Organ SizeTwins Monozygoticta3142Middle AgedHormonesConfidence intervalSurgerymedicine.anatomical_structureBody CompositionFemaleCortical boneDiaphysesSelf ReportbusinessJournal of Bone and Mineral Research
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