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showing 10 items of 6213 documents

One week of levofloxacin plus dexamethasone eye drops for cataract surgery: an innovative and rational therapeutic strategy

2020

Background: Cataract surgery is the most common operation performed worldwide. A fixed topical corticosteroid-antibiotic combination is usually prescribed in clinical practice for 2 or more weeks to treat post surgical inflammation and prevent infection. However, this protracted schedule may increase the incidence of corticosteroid-related adverse events and notably promote antibiotic resistance. Methods: This International, multicentre, randomized, blinded-assessor, parallel-group clinical study evaluated the non-inferiority of 1-week levofloxacin/dexamethasone eye drops, followed by 1-week dexamethasone alone, vs. 2-week gold-standard tobramycin/dexamethasone (one drop QID for all schedul…

medicine.medical_specialtymedicine.medical_treatmentLevofloxacinArticleDexamethasoneCataract03 medical and health sciences0302 clinical medicineEndophthalmitisPharmacotherapyPostoperative ComplicationsLevofloxacinInternal medicinemedicineTobramycinClinical endpointHumansEndophthalmitis Cataract Intracameral cefuroximeAdverse effectDexamethasoneEndophthalmitisbusiness.industryCataract surgeryIntracameral cefuroximemedicine.diseasenot applicableAnti-Bacterial AgentsOphthalmologyItalySpain030221 ophthalmology & optometryOphthalmic Solutionsbusiness030217 neurology & neurosurgerymedicine.drug
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Evaluation of routine follow-up after surgery for breast carcinoma.

1986

Close postoperative follow-up of patients with breast cancer permits the early detection of possible recurrence of disease. Such follow-up allows for the detection of a tumor mass, that is small enough to permit adequate treatment leading to an increased survival time and better quality of life. Thus we studied 85 patients treated by radical mastectomy in stages I, II, and III during the period from December 1977 to June 1982. Among 82 patients, 41 had axillary node involvement and received adjuvant chemotherapy with C.M.F. All patients received a strict follow-up. Thirty-two patients showed recurrence of the disease, with 28. 1% being discovered while still asymptomatic. Seventy-five perce…

medicine.medical_specialtymedicine.medical_treatmentMammary glandEarly detectionBreast NeoplasmsDiseaseAsymptomaticBreast cancerQuality of lifeMedicineHumansNeoplasm MetastasisRadical mastectomyPostoperative Carebusiness.industryGeneral Medicinemedicine.diseaseSurgerymedicine.anatomical_structureOncologySurgeryFemalemedicine.symptomNeoplasm Recurrence LocalbusinessBreast carcinomaFollow-Up StudiesJournal of surgical oncology
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Group psychoeducation with relaxation for severe fear of childbirth improves maternal adjustment and childbirth experience – a randomised controlled …

2014

Previous studies on the treatment of women with fear of childbirth have focused on the delivery mode. Women with fear of childbirth often suffer from anxiety and/or depression, and treatment therefore also needs to target postnatal psychological well-being and the early mother-infant relationship.Three hundred and seventy-one nulliparous women out of 4575 scored ≥100 in prospective screening (Wijma Delivery Expectancy Questionnaire, W-DEQ-A), indicating severe fear of childbirth. These women were randomised to psychoeducative group intervention with relaxation (n = 131; six sessions during pregnancy, one postnatal) or to conventional care (n = 240) by community nurses (referral if necessary…

medicine.medical_specialtymedicine.medical_treatmentMothersRelaxation TherapyPatient Education as TopicPregnancySurveys and QuestionnairesAdaptation PsychologicalPsychoeducationmedicineHumansChildbirthPsychiatryta515Pregnancybusiness.industryPostpartum PeriodParturitionSocial SupportObstetrics and GynecologyFearMaternal adjustmentChildbirth experienceDelivery ObstetricDelivery modemedicine.diseaseta3123Postnatal depressionPregnancy ComplicationsPsychiatry and Mental healthClinical PsychologyPost traumatic stress syndromeReproductive MedicineFear of childbirthEdinburgh Postnatal Depression ScalePsychotherapy GroupAnxietyFemalePregnant Womenmedicine.symptombusinessPsychosocialPostpartum periodJournal of Psychosomatic Obstetrics & Gynecology
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Robotic Versus Laparoscopic Staging for Early Ovarian Cancer: A Case-Matched Control Study.

2017

Abstract Study Objective To evaluate the feasibility, surgical outcome, and oncologic results observed after robotic staging compared with conventional laparoscopic staging for patients with early-stage ovarian cancer patients. Design A retrospective cohort study (Canadian Task Force classification II-2). Setting Catholic University of the Sacred Heart, Rome, Italy. Patients Ninety-six patients underwent minimally invasive staging for presumed stage I ovarian cancer; 32 underwent the robotic approach (cases), and 64 underwent the laparoscopic approach (controls). Measurements and Main Results There was no statistically significant difference between the 2 approaches with regard to final Fed…

medicine.medical_specialtymedicine.medical_treatmentOperative TimeHysterectomy03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRobotic Surgical ProceduresmedicineHumansRobotic surgeryStage (cooking)LaparoscopyAgedNeoplasm StagingRetrospective StudiesOvarian Neoplasms030219 obstetrics & reproductive medicineHysterectomymedicine.diagnostic_testbusiness.industryCase-control studyObstetrics and GynecologyRobotic Surgical ProceduresRobotic surgeryRetrospective cohort studyMiddle Agedmedicine.diseaseearly ovarian cancer; laparoscopy; robotic surgerySurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAOutcome and Process Assessment Health CareItaly030220 oncology & carcinogenesisCase-Control StudiesEarly ovarian cancerFemaleLaparoscopyOvarian cancerbusinessJournal of minimally invasive gynecology
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Real-world Adherence and Persistence with Bisphosphonate Therapy in Postmenopausal Women: A Systematic Review

2018

Abstract Purpose Bisphosphonate therapy is a well-established and effective treatment for postmenopausal osteoporosis and the prevention of osteoporotic fracture. However, poor adherence to and poor persistence with bisphosphonate therapy may reduce its benefits. Previous studies have documented the poor rates of adherence and persistence among postmenopausal women with osteoporosis. The objective of this systematic literature review was to evaluate adherence, persistence, and the impact of adherence and persistence on fracture risk in postmenopausal women with diagnosed osteoporosis. Methods Articles eligible for review included observational studies of the real-world use of bisphosphonate…

medicine.medical_specialtymedicine.medical_treatmentOsteoporosisMEDLINE02 engineering and technology030204 cardiovascular system & hematologyMedication AdherencePersistence (computer science)03 medical and health sciences020210 optoelectronics & photonics0302 clinical medicineInternal medicine0202 electrical engineering electronic engineering information engineeringmedicineHumansPharmacology (medical)Osteoporosis PostmenopausalPharmacologyBone Density Conservation AgentsDiphosphonatesbusiness.industryBisphosphonatemedicine.diseasePostmenopauseMenopauseObservational Studies as TopicTreatment OutcomeSystematic reviewFemaleObservational studybusinessOsteoporotic FracturesBiomedical sciencesClinical Therapeutics
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Improved femoral neck BMD in older Finnish women between 2002 and 2010.

2013

Abstract Purpose The number of hip fractures among Finns over 50-years of age rose constantly between 1970 and 1997, but since then, there has been a nationwide decline in incidence of hip fractures. One possible explanation, although not the only one, for the declining fracture rates, could be improved bone mineral density (BMD). The aim of this study was to evaluate differences in femoral neck BMD between older Finnish women born about a decade apart. Methods We compared the baseline data of two population-based samples of home-dwelling 70–80-year-old women who were initially recruited in exercise intervention studies ( N  = 216 in Cohort1, and N  = 389 in Cohort 2). Femoral neck BMD was …

medicine.medical_specialtymedicine.medical_treatmentOsteoporosisPopulationGeneral Biochemistry Genetics and Molecular BiologyCohort StudiesBone DensitymedicineHumanseducationFinlandOsteoporosis PostmenopausalFemoral neckAgedBone mineralAged 80 and overeducation.field_of_studyAnalysis of Variancebusiness.industryFemur NeckHip FracturesIncidence (epidemiology)IncidenceAge FactorsObstetrics and Gynecologyta3141Baseline datamedicine.diseaseBody Heightmedicine.anatomical_structureCohortPhysical therapyFemaleHormone therapybusinessDemographyMaturitas
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Altemeier's procedure for complete rectal prolapse; outcome and function in 43 consecutive female patients.

2019

Background The aim of this retrospective study was to evaluate morbidity, mortality, postoperative function and recurrences in patients treated by Altemeier’s rectosigmoidectomy for complete rectal prolapse in a referral center for pelvic floor functional disorders. Methods Peri-operative data on 43 consecutive female patients were reviewed. At follow-up any change in pelvic floor function and recurrences were determined. Thirty four patients were assessed at a median interval of 49 (2–135) months, six being deceased for reason not related to the prolapse and three lost to follow-up. Results Post-operative complications at 30 days occurred in 18 patients (38%). Major complication occurred i…

medicine.medical_specialtymedicine.medical_treatmentPelvic floor disorderslcsh:SurgeryUrinary incontinenceUrinary incontinence03 medical and health sciences0302 clinical medicinePatient satisfactionPostoperative Complicationsrectal prolapse; Altemeier procedure; perineal rectal resection; pelvic floor disorders; pelvic organ prolapse; fecal incontinence; urinary incontinenceRecurrenceFecal incontinenceMedicineFecal incontinenceHumansPostoperative PeriodDigestive System Surgical ProceduresAgedRetrospective StudiesRectal prolapseAged 80 and overHysterectomyPelvic floorbusiness.industryUrinary retentionRetrospective cohort studylcsh:RD1-811General MedicinePelvic Floormedicine.diseaseSurgeryPelvic organ prolapseRectal prolapse Altemeier procedure Perineal rectal resection Pelvic floor disorders Pelvic organ prolapse Fecal incontinence Urinary incontinenceRectal prolapsemedicine.anatomical_structureTreatment OutcomePatient Satisfaction030220 oncology & carcinogenesis030211 gastroenterology & hepatologySurgeryPerineal rectal resectionFemalemedicine.symptombusinessConstipationAltemeier procedureResearch Article
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Low-level laser therapy for treatment of neurosensory disorders after orthognathic surgery : a systematic review of randomized clinical trials

2017

Background Low-level laser has been widely used in Dentistry and many studies have focused on its application in oral surgeries. This study was conducted with the aim of searching for scientific evidence concerning the effectiveness of laser to reduce pain or paresthesia related to orthognathic surgery. Material and methods An electronic search was performed in PubMed, Scopus, Science Direct, LILACS, SciELO, CENTRAL, Google Scholar, OpenGrey, and ClinicalTrials.gov, up to November 2016, with no restrictions on language or year of publication. Additionally, a hand search of the reference list of the selected studies was carried out. The PICOS strategy was used to define the eligibility crite…

medicine.medical_specialtymedicine.medical_treatmentPostoperative painOrthognathic surgeryMEDLINEPlacebolaw.invention030207 dermatology & venereal diseases03 medical and health sciencesOrthognathic Surgical ProceduresPostoperative Complications0302 clinical medicineRandomized controlled triallawmedicineHumansParesthesiaLow-Level Light TherapyGeneral DentistryLow level laser therapyRandomized Controlled Trials as TopicPain PostoperativeOrthognathic Surgical Proceduresbusiness.industry030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Clinical trialOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPhysical therapySurgerybusiness
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Emergency hernia repair in the elderly: multivariate analysis of morbidity and mortality from an Italian registry

2020

Abstract Purpose The incidence of inguinal hernia is higher in elderly because of aging-related diseases like prostatism, bronchitis, collagen laxity. A conservative management is common in elderly to reduce surgery-related risks, however watchful waiting can expose to obstruction and strangulation. The aim of the present study was to assess the impact of emergency surgery in a large series of elderly with complicated groin hernia and to identify the independent risk factors for postoperative morbidity and mortality. The predictive performance of prognostic risk scores has been also assessed. Methods This is a prospective observational study carried out between January 2017 and June 2018 in…

medicine.medical_specialtymedicine.medical_treatmentSettore MED/18 - CHIRURGIA GENERALENOPostoperative complicationsElderlyLaparotomymedicineHerniaIncarcerated herniabusiness.industryExplorative laparotomyGroin hernia · Incarcerated hernia · Elderly · Postoperative complications · Emergency surgery · Charlson’s comorbidity indexmedicine.diseaseHernia repairComorbiditySurgeryGroin herniaInguinal herniaCharlson’s comorbidity indexEmergency surgerySurgerybusinessWatchful waitingCharlson’s comorbidity index; Elderly; Emergency surgery; Groin hernia; Incarcerated hernia; Postoperative complicationsAbdominal surgery
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Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and o…

2014

Background: Ischemic postconditioning (PCON) appears as a potentially beneficial tool in ST-segment elevation myocardial infarction (STEMI). We evaluated the effect of PCON on microvascular obstruction (MVO) in STEMI patients and in an experimental swine model. Methods: A prospective randomized study in patients and an experimental study in swine were carried out in two university hospitals in Spain. 101 consecutive STEMI patients were randomized to undergo primary angio-plasty followed by PCON or primary angioplasty alone (non-PCON). Using late gadolinium enhancement cardiovascular magnetic resonance, infarct size and MVO were quantified (% of left ventricular mass). In swine, using an ang…

medicine.medical_specialtymedicine.medical_treatmentlaw.inventionTECNOLOGIA ELECTRONICARandomized controlled triallawInternal medicineAngioplastymedicineIn patientMyocardial infarctioncardiovascular diseasesIschemic postconditioningEjection fractionmedicine.diagnostic_testExperimental modelbusiness.industryIschemic postconditioning Myocardial infarction PerfusionMagnetic resonance imagingmedicine.diseasePerfusionMyocardial infarctionsurgical procedures operativeCardiologyCardiology and Cardiovascular MedicinebusinessPerfusion
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