Search results for "prediction"
showing 10 items of 511 documents
Hybrid sequencing approach applied to human fecal metagenomic clone libraries revealed clones with potential biotechnological applications.
2012
Natural environments represent an incredible source of microbial genetic diversity. Discovery of novel biomolecules involves biotechnological methods that often require the design and implementation of biochemical assays to screen clone libraries. However, when an assay is applied to thousands of clones, one may eventually end up with very few positive clones which, in most of the cases, have to be "domesticated" for downstream characterization and application, and this makes screening both laborious and expensive. The negative clones, which are not considered by the selected assay, may also have biotechnological potential; however, unfortunately they would remain unexplored. Knowledge of t…
Comment on “Determining soil erodibility for the USLE-MM rainfall erosion model by P.I.A. Kinnell”
2018
Abstract The measurements units of the USLE-MM soil erodibility factor are dependent on the exponent of the erosivity term. This circumstance prevents to compare soil erodibility values of sites differing by the value of this exponent. To overcame this problem, Kinnell (2018) suggested to relate the soil erodibility factor of the USLE-MM with that of USLE-M by a linear relationship with the objective to obtain a soil erodibility factor independent of the power of the erosivity term. The USLE-MB, which is a recently proposed model, has also a soil erodibility factor having measurement units common to USLE modelling environment. Kinnell (2018) also showed that the relationship between the pow…
Early markers of language delay in children with and without family risk for dyslexia
2015
Accepted manuscript version. Published version at http://doi.org/10.1177/0142723715596122. This study examined the extent to which receptive and productive vocabulary between ages 12 and 18 months predicted language skills at age 24 months in children born with family risk for dyslexia (FR) and a control group born without that risk. The aim was to identify possible markers of early language delay. The authors monitored vocabulary growth in 32 FR children and 21 control children longitudinally by using the Norwegian adaption of the MacArthur–Bates Communicative Development Inventories. The results show different patterns in the two groups: the study found a stronger interdependence of early…
Dyslexia—Early Identification and Prevention: Highlights from the Jyväskylä Longitudinal Study of Dyslexia
2015
Over two decades of Finnish research, monitoring children born with risk for dyslexia has been carried out in the Jyvaskyla Longitudinal Study of Dyslexia (JLD). Two hundred children, half at risk, have been assessed from birth to puberty on hundreds of measures. The aims were to identify measures of prediction of later reading difficulty and to instigate appropriate and earliest diagnosis and intervention. We can identify at-risk children from newborn electroencephalographic brain recordings (Guttorm et al., J Neural Transm 110:1059–1074, 2003). Predictors are also apparent from late-talking infants who have familial background of dyslexia (Lyytinen and Lyytinen, Appl Psycolinguistics 25:3…
Management scenarios preventing salinization under irrigation with saline water.
2006
Management scenarios aimed at optimizing irrigation in a Sicilian vineyard characterized by a cracking clay soil irrigated with saline water were explored for seven soil profiles (Baglio 1-Baglio 7), by using the simulation model soil-water-atmosphere-plant environment (SWAP), which accounts for shrinkage and cracking. Accurate prediction of water content, theta, was obtained for the seven profiles by expressing the soil hydraulic properties according to the Brutsaert retention equation coupled with the hydraulic conductivity model proposed by Gardner (B-G model). A satisfactory prediction of the electrical conductivity of saturated extract (ECsat) ad was obtained using for the dispersivity…
Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies
2018
The development of depression may involve a complex interplay of environmental and genetic risk factors. PubMed and PsycInfo databases were searched from inception through August 3, 2017, to identify meta-analyses and Mendelian randomization (MR) studies of environmental risk factors associated with depression. For each eligible meta-analysis, we estimated the summary effect size and its 95% confidence interval (CI) by random-effects modeling, the 95% prediction interval, heterogeneity with I 2 , and evidence of small-study effects and excess significance bias. Seventy meta-analytic reviews met the eligibility criteria and provided 134 meta-analyses for associations from 1283 primary studie…
IMF lending arrangements in emerging and developing countries – participation and prediction
2016
AbstractThe literature on determinants of International Monetary Fund (IMF) interventions in emerging and developing countries shows that the IMF’s decisions are determined by political and economic causes. This article empirically investigates economic factors, showing that a country’s probability to sign an IMF arrangement can be predicted by looking at a core group of macroeconomic variables. Using discriminant analysis we develop a score function that allows us to predict a country’s future participation in IMF programmes. The study covers 153 emerging and developing countries, over more than 30 years (1980–2011) and 654 agreements, for both non-concessional and concessional loans. The …
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
2019
Crohn Disease (CD) is a complex genetic disorder for which more than 140 genes have been identified using genome wide association studies (GWAS). However, the genetic architecture of the trait remains largely unknown. The recent development of machine learning (ML) approaches incited us to apply them to classify healthy and diseased people according to their genomic information. The Immunochip dataset containing 18,227 CD patients and 34,050 healthy controls enrolled and genotyped by the international Inflammatory Bowel Disease genetic consortium (IIBDGC) has been re-analyzed using a set of ML methods: penalized logistic regression (LR), gradient boosted trees (GBT) and artificial neural ne…
Three-dimensional geometric morphometrics of thorax-pelvis covariation and its potential for predicting the thorax morphology: A case study on Kebara…
2020
The skeletal torso is a complex structure of outstanding importance in understanding human body shape evolution, but reconstruction usually entails an element of subjectivity as researchers apply their own anatomical expertise to the process. Among different fossil reconstruction methods, 3D geometric morphometric techniques have been increasingly used in the last decades. Two-block partial least squares analysis has shown great potential for predicting missing elements by exploiting the covariation between two structures (blocks) in a reference sample: one block can be predicted from the other one based on the strength of covariation between blocks. The first aim of this study is to test w…
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium
2016
Background Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting. Methods We performed a two-stage GWAS analysis of incident myocardial infarction (MI) and CHD in a total of 64,297 individuals (including 3898 MI cases, 5465 CHD cases). SNPs that passed an arbitrary threshold of 5×10−6 in Stage I were taken to Stage II for further discovery. Furthermore, in an analysis of prognosis, we studied whether known SNPs from former GWAS were associated with total mortality in individuals who experienced MI during follow-up. Res…