Search results for "probability"
showing 10 items of 3417 documents
Corrigendum: Partial inner product spaces, metric operators and generalized hermiticity
2013
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Influence of inorganic pyrophosphate on the kinetics of muscle pyruvate kinase: a simple nonallosteric feedback model.
2002
Potassium pyrophosphate was used instead of ATP as a model ligand for magnesium cation for the study of effector influence on the kinetics of pyruvate kinase muscle isozyme M1. The pyruvate kinase activation by low concentration of pyrophosphate and inhibition by high concentration of pyrophosphate was considered to be the result of reversible reactions of magnesium cation with pyrophosphate, ADP, ATP, and PEP. The apparent Km and Vm or in some cases the pseudo-first order reaction rate constant (instead of Km and Vm) of pyruvate kinase at any given pyrophosphate concentration were analysed as a function of concentration of free magnesium cation and its complexes with all ligands present in…
Updating input–output matrices: assessing alternatives through simulation
2009
A problem that frequently arises in economics, demography, statistics, transportation planning and stochastic modelling is how to adjust the entries of a matrix to fulfil row and column aggregation constraints. Biproportional methods in general and the so-called RAS algorithm in particular, have been used for decades to find solutions to this type of problem. Although alternatives exist, the RAS algorithm and its extensions are still the most popular. Apart from some interesting empirical and theoretical properties, tradition, simplicity and very low computational costs are among the reasons behind the great success of RAS. Nowadays computer hardware and software have made alternative proce…
SeqEditor: an application for primer design and sequence analysis with or without GTF/GFF files
2021
[Motivation]: Sequence analyses oriented to investigate specific features, patterns and functions of protein and DNA/RNA sequences usually require tools based on graphic interfaces whose main characteristic is their intuitiveness and interactivity with the user’s expertise, especially when curation or primer design tasks are required. However, interface-based tools usually pose certain computational limitations when managing large sequences or complex datasets, such as genome and transcriptome assemblies. Having these requirments in mind we have developed SeqEditor an interactive software tool for nucleotide and protein sequences’ analysis.
Intrinsic credible regions: An objective Bayesian approach to interval estimation
2005
This paper definesintrinsic credible regions, a method to produce objective Bayesian credible regions which only depends on the assumed model and the available data.Lowest posterior loss (LPL) regions are defined as Bayesian credible regions which contain values of minimum posterior expected loss: they depend both on the loss function and on the prior specification. An invariant, information-theory based loss function, theintrinsic discrepancy is argued to be appropriate for scientific communication. Intrinsic credible regions are the lowest posterior loss regions with respect to the intrinsic discrepancy loss and the appropriate reference prior. The proposed procedure is completely general…
Multiple smoothing parameters selection in additive regression quantiles
2021
We propose an iterative algorithm to select the smoothing parameters in additive quantile regression, wherein the functional forms of the covariate effects are unspecified and expressed via B-spline bases with difference penalties on the spline coefficients. The proposed algorithm relies on viewing the penalized coefficients as random effects from the symmetric Laplace distribution, and it turns out to be very efficient and particularly attractive with multiple smooth terms. Through simulations we compare our proposal with some alternative approaches, including the traditional ones based on minimization of the Schwarz Information Criterion. A real-data analysis is presented to illustrate t…
Wardowski conditions to the coincidence problem
2015
In this article we first discuss the existence and uniqueness of a solution for the coincidence problem: Find p ∈ X such that Tp = Sp, where X is a nonempty set, Y is a complete metric space, and T, S:X → Y are two mappings satisfying a Wardowski type condition of contractivity. Later on, we will state the convergence of the Picard-Juncgk iteration process to the above coincidence problem as well as a rate of convergence for this iteration scheme. Finally, we shall apply our results to study the existence and uniqueness of a solution as well as the convergence of the Picard-Juncgk iteration process toward the solution of a second order differential equation. Ministerio de Economía y Competi…
Dissipation and entanglement dynamics for two interacting qubits coupled to independent reservoirs
2008
We derive the master equation of a system of two coupled qubits by taking into account their interaction with two independent bosonic baths. Important features of the dynamics are brought to light, such as the structure of the stationary state at general temperatures and the behaviour of the entanglement at zero temperature, showing the phenomena of sudden death and sudden birth as well as the presence of stationary entanglement for long times. The model here presented is quite versatile and can be of interest in the study of both Josephson junction architectures and cavity-QED.
Clustering of spatial point patterns
2006
Spatial point patterns arise as the natural sampling information in many problems. An ophthalmologic problem gave rise to the problem of detecting clusters of point patterns. A set of human corneal endothelium images is given. Each image is described by using a point pattern, the cell centroids. The main problem is to find groups of images corresponding with groups of spatial point patterns. This is interesting from a descriptive point of view and for clinical purposes. A new image can be compared with prototypes of each group and finally evaluated by the physician. Usual descriptors of spatial point patterns such as the empty-space function, the nearest distribution function or Ripley's K-…
Local bandwidth selection for kernel density estimation in a bifurcating Markov chain model
2020
International audience; We propose an adaptive estimator for the stationary distribution of a bifurcating Markov Chain onRd. Bifurcating Markov chains (BMC for short) are a class of stochastic processes indexed by regular binary trees. A kernel estimator is proposed whose bandwidths are selected by a method inspired by the works of Goldenshluger and Lepski [(2011), 'Bandwidth Selection in Kernel Density Estimation: Oracle Inequalities and Adaptive Minimax Optimality',The Annals of Statistics3: 1608-1632). Drawing inspiration from dimension jump methods for model selection, we also provide an algorithm to select the best constant in the penalty. Finally, we investigate the performance of the…