Search results for "programming."

New Directions for Use of Systemic Drug Delivery in Anti-aging Medicine

2020

Abstract Anti-aging medicine has become a popular topic in recent years. It considers biological aging a revertible process that physiologically serves no posi tive function. Different technologies in systemic delivery and various strategies that characterize and optimize the performance of systemic delivery have been covered in this book. These technologies are essential for the establishment of a technical platform for interventive biogerontology. As the last chapter of this book, we would like to highlight some directions for future applications of systemic drug delivery in anti-aging medicine. We believe that biological aging and aging-related diseases are strongly associated with genet…

Selecting the best risk measure in multiobjective cash management

2018

Fuzzy Metric Approach to Aggregation of Risk Levels

2019

In this paper we propose a special construction of a general aggregation operator. The construction allows to aggregate fuzzy sets taking into account the distance between elements of the universe. We consider the case when fuzzy sets to be aggregated represent the risk level evaluation by several experts. We describe how the proposed construction could be applied for risk level assessment in the case when a strong fuzzy metric is used to characterize the similarity of objects under evaluation.

Stochastic debt sustainability analysis for sovereigns and the scope for optimization modeling

2017

We express the opinion that sovereign debt sustainability analysis must be augmented by stochastic correlated risk factors and a risk measure to capture tail effects. Crisis situations can thus be adequately specified and analyzed with sufficient accuracy to warrant the relevance of policy decisions. In this context there is significant scope for optimization modeling for both strategic planning and operational management. We discuss diverse aspects of the problem of debt sustainability and highlight modeling approaches that can be brought to bear on the problem. Results with the fictitiuous, but nor unrealistic, Kingdom of Atlantis, which is sinking under excessive debt, illustrate the pro…

Determining the appropriate timing of the next forest inventory: incorporating forest owner risk preferences and the uncertainty of forest data quali…

2017

Key message The timing to conduct new forest inventories should be based on the requirements of the decision maker. Importance should be placed on the objectives of the decision maker and his/her risk preferences related to those objectives. Context The appropriate use of pertinent and available information is paramount in any decision-making process. Within forestry, a new forest inventory is typically conducted prior to creating a forest management plan. The acquisition of new forest inventory data is justified by the simple statement of “good decisions require good data.” Aims By integrating potential risk preferences, we examine the specific needs to collect new forest information. Meth…

Is integration of Uncertainty Management and The Last Planner System a good idea?

2018

The Last Planner System (LPS) is a tool for project planning and control, and is an important contribution from Lean Construction. LPS focuses on scheduling, task coordination and time management. Uncertainty Management (UM) is a key element in Project Management, where uncertainty is the totality of opportunities (potential upsides) and risks (potential downsides). UM addresses all types of uncertainty (related to cost, time, quality, scope, safety, customer satisfaction, company reputation, etc.). The aim of UM is to exploit the opportunities and reduce the risks. Two construction companies involved in this research are working with both LPS and UM. One has extensive experience with LPS, …

Semi-automatic Quasi-morphological Word Segmentation for Neural Machine Translation

2018

This paper proposes the Prefix-Root-Postfix-Encoding (PRPE) algorithm, which performs close-to-morphological segmentation of words as part of text pre-processing in machine translation. PRPE is a cross-language algorithm requiring only minor tweaking to adapt it for any particular language, a property which makes it potentially useful for morphologically rich languages with no morphological analysers available. As a key part of the proposed algorithm we introduce the ‘Root alignment’ principle to extract potential sub-words from a corpus, as well as a special technique for constructing words from potential sub-words. We conducted experiments with two different neural machine translation sys…

A Novel Fault-Tolerant Routing Technique for Mesh-of-Tree based Network-on-Chip Design

2018

Due to the increase in the number of processing elements in System-on-Chips (SoCs), communication between the cores is becoming complex. A solution to this issue in SoCs gave rise to a new paradigm called Network-on-Chips (NoCs). In NoCs, communication between different cores is achieved using packet based switching techniques. In the deep sub-micron technology, NoCs are more susceptible to different kinds of faults which can be transient, intermittent and permanent. These faults can occur at any component of NoCs. This paper presents a novel Fault-Tolerant Routing (FTR) technique for Mesh-of-Tree (MoT) topology in the presence of router faults. The proposed technique is compared with routi…

Architectural Implementation of a Reconfigurable NoC Design for Multi-Applications

2021

With the increasing number of applications running on a Network-on-Chip (NoC) based System-on-Chip (SoC), there is a need for designing a reconfigurable NoC platform to achieve acceptable performance for all the applications. This paper proposes a novel architecture for implementing a reconfiguration logic to the NoC platform executing multiple applications. The proposed architecture reconfigures SoC modules to the routers in the NoC with the help of tri-state buffers based on the applications running. The overhead in implementing the reconfiguration circuitry is significantly less, approximately 0.9% of the area and 1% of the total power consumed by the router network. The architectures pr…

Flexible Spare Core Placement in Torus Topology based NoCs and its validation on an FPGA

2021

In the nano-scale era, Network-on-Chip (NoC) interconnection paradigm has gained importance to abide by the communication challenges in Chip Multi-Processors (CMPs). With increased integration density on CMPs, NoC components namely cores, routers, and links are susceptible to failures. Therefore, to improve system reliability, there is a need for efficient fault-tolerant techniques that mitigate permanent faults in NoC based CMPs. There exists several fault-tolerant techniques that address the permanent faults in application cores while placing the spare cores onto NoC topologies. However, these techniques are limited to Mesh topology based NoCs. There are few approaches that have realized …