Search results for "programming"
showing 10 items of 3090 documents
The art of forging neurons: direct reprogramming of somatic cells into induced neuronal cells
2013
Abstract Cellular reprogramming has shed new light on the plasticity of terminally differentiated cells and unearthed novel strategies for cell-based therapies to treat neurological disorders. With accumulating knowledge of the programs underlying the genesis of the distinct neural cell types, particularly the identification of crucial transcription factors and microRNAs, reprogramming of somatic cells of different origins into induced neuronal cells or neural stem cells has been successfully achieved. Starting with the general concept of reprogramming, we discuss three different paradigms: (1) direct conversion of central nervous system (CNS) foreign cells such as skin fibroblasts in…
Computing Real-Time Dynamic Origin/Destination Matrices from Vehicle-to-Infrastructure Messages Using a Multi-Agent System
2012
Dynamic Origin/Destination matrices are one of the most important parameters for efficient and effective transportation system management. These matrices describe the vehicle flow between different points within a region of interest for a given period of time. Usually, dynamic O/D matrices are estimated from traffic counts provided by induction loop detectors, home interview and/or license plate surveys. Unfortunately, estimation methods take O/D flows as time invariant for a certain number of intervals of time, which cannot be suitable for some traffic applications. However, the advent of information and communication technologies (e.g., vehicle-to-infrastructure dedicated short range comm…
Extended complex Kalman filter for sensorless control of an induction motor
2014
Abstract This paper deals with the design of an extended complex Kalman filter (ECKF) for estimating the state of an induction motor (IM) model, and for sensorless control of systems employing this type of motor as an actuator. A complex-valued model is adopted that simultaneously allows a simpler observability analysis of the system and a more effective state estimation. The observability analysis of this model is first performed by assuming that a third order ECKF has to be designed, by neglecting the mechanical equation of the IM model, which is a valid hypothesis when the motor is operated at constant rotor speed. It is shown that this analysis is more effective and easier than the one …
Chairs' welcome message
2004
In this paper we present techniques for comparison between behavioral level and register transfer level (RTL) design descriptions by mapping the designs into virtual controllers and virtual datapaths. We also discuss about how the equivalence between behavioral level and RTL designs can be defined precisely using the proposed "attribute statements" in an interactive fashion. Implementation issues as well as considerations on real life industrial design examples are presented as well.
Enabling robotic adaptive behaviour capabilities for new industry 4.0 automated quality inspection paradigms
2020
The seamless integration of industrial robotic arms with server computers, sensors and actuators can revolutionise the way in which automated non-destructive testing (NDT) is performed and conceived. Achieving effective integration and realising the full potential of robotic systems presents significant challenges, since robots, sensors and end-effector tools are often not necessarily designed to be put together and form a holistic system. This paper presents recent breakthroughs, opening up new scenarios for the inspection of product quality in advanced manufacturing. Many years of research have brought to software platforms the ability to integrate external data acquisition instrumentatio…
Ovulation induction and epigenetic anomalies
2013
In this systematic review of ovulation induction and epigenetic control, studies mainly done in the mouse model highlight how hormone treatments may be prejudicial to the epigenetic reprogramming of gametes as well as early embryos. Moreover, the hormone protocols used in assisted reproduction may also modify the physiologic environment of the uterus, a potential link to endometrial epigenetic disturbances. At present, the few available data in humans are insufficient to allow us to independently determine the impact of a woman's age and infertility problems and treatment protocols and hormone doses on such processes as genomic imprinting.
Toward a formalization of a two traders market with information exchange
2014
This paper shows that Hamiltonians and operators can also be put to good use even in contexts which are not purely physics based. Consider the world of finance. The work presented here {models a two traders system with information exchange with the help of four fundamental operators: cash and share operators; a portfolio operator and an operator reflecting the loss of information. An information Hamiltonian is considered and an additional Hamiltonian is presented which reflects the dynamics of selling/buying shares between traders. An important result of the paper is that when the information Hamiltonian is zero, portfolio operators commute with the Hamiltonian and this suggests that the dy…
Online Academic Networks as Knowledge Brokers: The Mediating Role of Organizational Support
2018
Placing online academic networks in the framework of social, cultural and institutional “deterritorialization,” the current paper aims at investigating the functionality of these new forms of transnational and trans-organizational aggregations as knowledge brokers. The emphasis is laid on the influence of human collective intelligence and consistent knowledge flows on research innovation, considering the role of organizational support within higher education systems. In this respect, the research relied on a questionnaire-based survey with 140 academics from European emerging countries, the data collected being processed via a partial least squares structural equation modelling technique. E…
2020
Abstract Interest in studying information systems discontinuance has been increasing lately, yet there is no consensus on what it means. To improve the situation, we conduct a comprehensive review of current literature on IS discontinuance and identify 55 studies published during 1991–2017 that specifically focus on the topic. Our conceptual analysis disentangles the process, content, and context of the phenomenon, revealing that over the course of a typical IS lifecycle, IS discontinuance may materialize at least in five distinct forms: rejection, regressive discontinuance, quitting, temporary discontinuance, and replacement. After elaborating their distinctions, we discuss their theoretic…
Adaptive memory programming for the dynamic bipartite drawing problem
2020
Abstract The bipartite drawing problem is a well-known NP-hard combinatorial optimization problem with numerous applications. The aim is to minimize the number of edge crossings in a two-layer graph, in which the edges are drawn as straight lines. We consider the dynamic variant of this problem, called the dynamic bipartite drawing problem (DBDP), which consists of adding (resp. or removing) vertices and edges to (resp. or from) a given bipartite drawing, thereby obtaining a new drawing with a layout similar to that of the original drawing. To solve this problem, we propose a tabu search method that incorporates adaptive memory to search the solution space efficiently. In this study, we com…