Search results for "prospective"

showing 10 items of 3738 documents

Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery …

2020

BACKGROUND: The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery. MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin was selected for this split mouth randomized controlled and double-blind trial including 36 patients with bilaterally and symmetrically impacted lower third molars. The teeth (n=72) were randomly divided into two groups before surgical removal: control group (CG; in which a placebo was given) and experimental group (EG). …

MolarallantoinTrismusPantothenic Acidsurgerychemistry.chemical_compound0302 clinical medicineEdemaMedicinepainProspective StudiesBIOADHESIVE GELAllantoinPain PostoperativeChlorhexidinechlorhexidineTooth Impactedpostoperative wound healing:CIENCIAS MÉDICAS [UNESCO]Dry socketIThird molarAnesthesiaUNESCO::CIENCIAS MÉDICASOral Surgerymedicine.symptomDexpanthenolLife Sciences & Biomedicinemedicine.druggeldexpanthenolEXTRACTIONPlacebo03 medical and health sciencesAllantoinDouble-Blind MethodDentistry Oral Surgery & MedicineHumansGeneral DentistryInflammationChitosanScience & Technologybusiness.industryResearchINTRAALVEOLAR PLACEMENTChlorhexidine030206 dentistrymedicine.diseaseALVEOLAR OSTEITISPREVENTIONClinical trialOtorhinolaryngologychemistryTooth ExtractionMolar ThirdTrismusSurgerychitosanbusiness
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Influence of operator’s professional experience in the postoperative course after surgical extrac-tion of the impacted lower third molar: A pilot stu…

2020

Background Third molars are present in 96.6% of humans, although they do not always erupt completely. Between 9.5% and 73% of them remain impacted. Surgical removal of impacted third molars is the most common practice in oral and maxillofacial surgery. This procedure results in traumatism and, consequently, the postoperative phase will involve symptomatology. It is uncommon to find studies that directly relate postoperative symptomatology and the operator's experience. The aim of this study was to determine the differences regarding postoperative symp-tomatology in patients undergoing the bilateral extraction of lower impacted third molars and according to the operator's experience. Materia…

Molarbusiness.industryResearchmedicine.medical_treatmentDentistry030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Trismus03 medical and health sciences0302 clinical medicineDental extractionSurgical removalUNESCO::CIENCIAS MÉDICASmedicineOral and maxillofacial surgeryIn patientLocal anesthesiaOral Surgerymedicine.symptom030223 otorhinolaryngologybusinessProspective cohort studyGeneral DentistryJournal of Clinical and Experimental Dentistry
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Effect of preemptive dexamethasone and etoricoxib on postoperative period following impacted third molar surgery - a randomized clinical trial.

2019

Background The aim of this study was to compare the anti-inflammatory effects of dexamethasone and etoricoxib after third molar extraction. Material and Methods A prospective, randomized, controlled, split-mouth study was conducted. 19 volunteers were allocated randomly to receive 90mg etoricoxib 1 hour prior to the procedure or 4mg intramuscular dexamethasone immediately after anesthesia. Baseline measurements were obtained preoperatively, and subsequent assessments were made on immediate postoperative, at 72 hours and 7 days after surgery to measure postoperative facial swelling by use of linear measurements, interincisal mouth opening width and visual analog scale score for pain. The amo…

Molarmedicine.drug_classAnti-Inflammatory AgentsTrismusDexamethasonelaw.invention03 medical and health sciencesEtoricoxib0302 clinical medicineRandomized controlled trialDouble-Blind MethodlawStatistical significanceMedicineEdemaHumansProspective StudiesProspective cohort studyGeneral DentistryDexamethasonePain MeasurementPain Postoperativebusiness.industryResearchTooth Impacted030206 dentistry:CIENCIAS MÉDICAS [UNESCO]OtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASTooth ExtractionCorticosteroidSurgeryMolar ThirdTrismusmedicine.symptomOral SurgerybusinessEtoricoxibmedicine.drugMedicina oral, patologia oral y cirugia bucal
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Influence of surgical ultrasound used in the detachment of flaps, osteotomy and odontosection in lower third molar surgeries. A prospective, randomiz…

2020

Made available in DSpace on 2020-12-10T20:04:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: As third molar surgery is the most commonly procedure performed in Dentistry and has been accompanied by serious postoperative disorders such as pain edema and trismus, the study aimed to evaluate if ultrasound device would be able to reduce such postoperative features. The aim of this study was to assess the effects of soft tissue flap elevation, osteotomy and odontosection using piezosurgery versus conventional technique in mandibular third molar extractions. Material and Methods: Twenty patients with impacte…

Molarmedicine.medical_specialtymedicine.medical_treatmentpiezosurgeryTrismusOsteotomySurgical Flaps03 medical and health sciences0302 clinical medicinestomatognathic systemexodontiaThird molarmedicineEdemaHumansProspective StudiesOstectomyProspective cohort studyGeneral DentistryPiezosurgeryMouthPain PostoperativeOral Medicine and Pathologybusiness.industryResearchUltrasoundTooth ImpactedSoft tissue030206 dentistry:CIENCIAS MÉDICAS [UNESCO]OsteotomySurgeryostectomyOtorhinolaryngologyTooth ExtractionUNESCO::CIENCIAS MÉDICASMolar ThirdTrismusSurgerymedicine.symptomflapbusinessMedicina Oral Patología Oral y Cirugia Bucal
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Prospective study of monolithic zirconia crowns: clinical behavior and survival rate at a 5-year follow-up

2020

Purpose To evaluate the clinical behavior and survival of full coverage monolithic zirconia crowns on posterior teeth over a 5-year follow-up. Methods Fifty patients were recruited and underwent restoration with a Lava Plus monolithic zirconia crown (Lava™ Frame Zirconia, 3M Espe, Germany) on premolars or molars. Patients were monitored over a 5-year follow-up (2014-19), recording any biological and/or mechanical complications; these data were used to estimate the crowns' success rate. Periodontal clinical parameters were recorded (pocket probing depth (PPD), plaque index (PLI), bleeding on probing (BOP), and gingival recession (GR)). Wear to the zirconia crowns and antagonist teeth were al…

Molarmedicine.medical_treatment0206 medical engineeringBleeding on probingDentistry02 engineering and technologyCrown (dentistry)03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineHumansDentistry (miscellaneous)Dental Restoration FailureProspective StudiesSurvival rateGingival recessionDental structureCrownsEnamel paintbusiness.industry030206 dentistry020601 biomedical engineeringSurvival Ratestomatognathic diseasesvisual_artvisual_art.visual_art_mediumPosterior teethZirconiumOral Surgerymedicine.symptombusinessFollow-Up StudiesJournal of Prosthodontic Research
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Molecular spreading and predictive value of preclinical IgE response to Phleum pratense in children with hay fever.

2012

Background IgE sensitization against grass pollen is a cause of seasonal allergic rhinitis. Objective We sought to investigate the evolution at the molecular level and the preclinical predictive value of IgE responses against grass pollen. Methods The German Multicentre Allergy Study examined a birth cohort born in 1990. A questionnaire was administered yearly, and blood samples were collected at 1, 2, 3, 5, 6, 7, 10, and 13 years of age. Grass pollen–related seasonal allergic rhinitis (SARg) was diagnosed according to nasal symptoms in June/July. Serum IgE antibodies to Phleum pratense extract and 8 P pratense molecules were tested with immune-enzymatic singleplex and multiplex assays, res…

Molecular complexityMaleImmunologyImmunoglobulin EPhleumCohort StudiesPredictive Value of TestsGrass pollenmedicineImmunology and AllergyHumansProspective StudiesChildTimothy-grassbiologybusiness.industryInfantRhinitis Allergic SeasonalImmunoglobulin Ebiology.organism_classificationmedicine.diseasePredictive valueChild PreschoolPhleumImmunologybiology.proteinHay feverFemaleAntibodybusinessThe Journal of allergy and clinical immunology
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Ultrasound protocol in odontogenic infections: a new proposal

2022

Point-of-care-ultrasound can be applied to preview a difficult airway, detect the presence of fluid collection, and soft-tissue edema, and guide the drainage location, although is rarely used. The purpose of this study is to validate a protocol for the assessment of these clinical features on patients with severe odontogenic infections. This was a single-group prospective cohort study (n=20) including patients with the diagnosis of deep-neck propagation of odontogenic infection. A transcervical linear high-frequency probe transducer (13-6 MHz) was used to scan the structures of the upper airway and the infectious collections. The drainage was guided by ultrasound and the patients were daily…

Mouthdescending necrotizing mediastinitisInfection Control Dentalmortality rateInfectionsHospitalizationcervical abscessDyspneaacute mediastinitisOtorhinolaryngologyPoint-of-Care TestingDentistryHumansSurgeryProspective StudiesDeglutition Disordersodontogenic infectionGeneral DentistryNeckUNESCO:CIENCIAS MÉDICASUltrasonographyMedicina Oral Patología Oral y Cirugia Bucal
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International validation of the revised European Organisation for Research and treatment of cancer head and neck cancer module, the EORTC QLQ-HN43

2019

Background: We validated the new European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC QLQ-HN43). Methods: We enrolled 812 patients with head and neck cancer from 18 countries. Group 1 completed the questionnaire before therapy, and 3 and 6 months later. In group 2 (survivors), we determined test–retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed using Cronbach's Alpha, the scale structure with confirmatory factor analysis, and discriminant validity with known-group comparisons. Results: Cronbach's alpha was >0.70 in 10 of the 12 multi-item scales. All standardized factor loadings exceeded…

Multimodal therapiesQuality of lifeMalemedicine.medical_specialtySDG 16 - PeacePsychometricsIntraclass correlationMedizinSensitivity and Specificity03 medical and health sciences0302 clinical medicineCronbach's alphaQuality of lifeSurveys and QuestionnairesValidationOutcome Assessment Health CaremedicineHumansProspective Studies030212 general & internal medicineHead and neck cancerReliability (statistics)AgedAged 80 and overbusiness.industryHead and neck cancerSDG 16 - Peace Justice and Strong InstitutionsDiscriminant validityReproducibility of ResultsCancerMiddle Agedmedicine.diseaseCombined Modality Therapy/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsConfirmatory factor analysishumanitiesJustice and Strong Institutions3. Good healthEuropeChemoradiationOtorhinolaryngologyHead and Neck Neoplasms030220 oncology & carcinogenesisQuality of LifePhysical therapyFemalebusinessHead and Neck
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Investigating the possible impact of peritoneal tumor exposure amongst women with early stage cervical cancer treated with minimally invasive approac…

2021

Abstract Introduction Recent findings show a detrimental impact of the minimally invasive approach on patients with early stage cervical cancer (ECC). Reasons beyond these results are unclear. The aim of the present article is to investigate the possible role of peritoneal contamination during intracorporeal colpotomy. Methods patients with early stage cervical cancer were divided into 2 groups: no intraperitoneal exposure (N-IPE) intraperitoneal exposure (IPE) during minimally invasive surgery. Patients of the 2 groups were propensity-matched according to the major risk factors. Results 226 cases of the IPE group had a significant worst prognosis than the 142 cases of the N-IPE group (4.5-…

Multivariate analysisPeritoneal tumorUterine Cervical NeoplasmsColpotomy0302 clinical medicineRisk Factors80 and overRadical hysterectomyStage (cooking)Prospective cohort studyLaparoscopyPeritoneal CavityCervical cancerAged 80 and over030219 obstetrics & reproductive medicinemedicine.diagnostic_testHazard ratioCervical cancer; Laparoscopy; Minimally invasive; Peritoneal contamination; Radical hysterectomyGeneral MedicineMiddle AgedPrognosisSurvival RateOncologyItaly030220 oncology & carcinogenesisPeritoneal contaminationLymphatic MetastasisFemaleAdultmedicine.medical_specialty03 medical and health sciencesInternal medicinemedicineHumansMinimally Invasive Surgical ProceduresMinimally invasivePropensity ScoreAgedNeoplasm StagingRetrospective Studiesbusiness.industrymedicine.diseaseConfidence intervalSettore MED/40 - GINECOLOGIA E OSTETRICIACervical cancerLymph Node ExcisionSurgeryLaparoscopyNeoplasm GradingbusinessEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Orphan symptoms in advanced cancer patients followed at home

2013

Abstract Orphan symptoms are rarely assessed, particularly at home. The aim of this multicenter prospective study was to assess the prevalence of these symptoms and eventual factors possibly associated in advanced cancer patients at admission of a home care program. A prospective study was performed at three home care programs in Italy. Patients' data were collected, including age, sex, diagnosis, and Karnofsky status. Possible contributing factors were analyzed; preexisting neurological diseases, cerebral metastases, hyperthermia, diabetes, a state of dehydration clinically evident and/or oliguria, possible biochemical parameters when available, data regarding recent chemotherapy, opioids …

MyoclonusMalemedicine.medical_specialtyPalliative careHiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; Tenesmus; Aged; Analgesics Opioid; Female; Fentanyl; Hiccup; Home Care Services; Hospitalization; Humans; Italy; Karnofsky Performance Status; Male; Myoclonus; Neoplasms; Prospective Studies; Pruritus; Sweating; Oncology; Medicine (all)Hiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; TenesmusSweatingOpioidSettore MED/42 - Igiene Generale E ApplicataHome careFentanylHiccupPrurituOliguriaInternal medicineDiabetes mellitusNeoplasmsMedicineHumansVesical tenesmusProspective StudiesKarnofsky Performance StatusProspective cohort studyAgedAnalgesicsbusiness.industryPruritusMedicine (all)Tenesmusmedicine.diseaseHome Care ServicesAnalgesics OpioidFentanylHospitalizationDistressItalyOncologyAnesthesiaPalliative careFemalemedicine.symptombusinessMyoclonusMyoclonumedicine.drug
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